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Items: 1 to 20 of 131

1.

Two novel NPM1 mutations in a therapy-responder AML patient.

Pianta A, Fabbro D, Damiani D, Tiribelli M, Fanin R, Franzoni A, Romanello M, Tell G, Di Loreto C, Damante G.

Hematol Oncol. 2010 Sep;28(3):151-5. doi: 10.1002/hon.906.

PMID:
19593743
2.

Acute myeloid leukemia with mutated nucleophosmin (NPM1): molecular, pathological, and clinical features.

Falini B.

Cancer Treat Res. 2010;145:149-68. doi: 10.1007/978-0-387-69259-3_9.

PMID:
20306250
3.

Cytoplasmic expression of nucleophosmin accurately predicts mutation in the nucleophosmin gene in patients with acute myeloid leukemia and normal karyotype.

Luo J, Qi C, Xu W, Kamel-Reid S, Brandwein J, Chang H.

Am J Clin Pathol. 2010 Jan;133(1):34-40. doi: 10.1309/AJCPCI1FFE2DRXIV.

4.

Acute myeloid leukemia with mutated nucleophosmin (NPM1): any hope for a targeted therapy?

Falini B, Gionfriddo I, Cecchetti F, Ballanti S, Pettirossi V, Martelli MP.

Blood Rev. 2011 Nov;25(6):247-54. doi: 10.1016/j.blre.2011.06.001. Epub 2011 Jul 2. Review.

PMID:
21724308
5.

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication.

Paschka P, Schlenk RF, Gaidzik VI, Habdank M, Krönke J, Bullinger L, Späth D, Kayser S, Zucknick M, Götze K, Horst HA, Germing U, Döhner H, Döhner K.

J Clin Oncol. 2010 Aug 1;28(22):3636-43. doi: 10.1200/JCO.2010.28.3762. Epub 2010 Jun 21.

6.

NPM1 mutations in myelodysplastic syndromes and acute myeloid leukemia with normal karyotype.

Zhang Y, Zhang M, Yang L, Xiao Z.

Leuk Res. 2007 Jan;31(1):109-11. Epub 2006 May 5.

PMID:
16678898
7.

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).

Thiede C, Koch S, Creutzig E, Steudel C, Illmer T, Schaich M, Ehninger G.

Blood. 2006 May 15;107(10):4011-20. Epub 2006 Feb 2.

8.

[Research on NPM1 gene mutations in acute myeloid leukemia].

Chen HY, Lu QY.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013 Feb;21(1):258-62. doi: 10.7534/j.issn.1009-2137.2013.01.053. Review. Chinese.

PMID:
23484732
9.

[Analysis of NPM1 gene mutations in acute myeloid leukemia].

Yan LZ, Chen SN, Liang JY, Feng YF, Cen JN, He J, Chang WR, Zhu ZL, Pan JL, Wu YF, Xue YQ, Wu DP.

Zhonghua Xue Ye Xue Za Zhi. 2007 May;28(5):289-93. Chinese.

PMID:
17877154
10.

Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.

Falini B, Bolli N, Liso A, Martelli MP, Mannucci R, Pileri S, Nicoletti I.

Leukemia. 2009 Oct;23(10):1731-43. doi: 10.1038/leu.2009.124. Epub 2009 Jun 11. Review.

PMID:
19516275
11.

Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype.

Cazzaniga G, Dell'Oro MG, Mecucci C, Giarin E, Masetti R, Rossi V, Locatelli F, Martelli MF, Basso G, Pession A, Biondi A, Falini B.

Blood. 2005 Aug 15;106(4):1419-22. Epub 2005 May 3.

12.

Clinical impact of nucleophosmin mutations and Flt3 internal tandem duplications in patients older than 60 yr with acute myeloid leukaemia.

Scholl S, Theuer C, Scheble V, Kunert C, Heller A, Mügge LO, Fricke HJ, Höffken K, Wedding U.

Eur J Haematol. 2008 Mar;80(3):208-15.

PMID:
18081718
13.

[Analysis of NPM1 gene mutations in acute myeloid leukemia].

Dai D, Zhang SJ, Qiao C, Sun XM, Qian SX, Xu W, Xu YL, Li JY.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Apr;17(2):294-7. Chinese.

PMID:
19379554
15.

Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia.

Suzuki T, Kiyoi H, Ozeki K, Tomita A, Yamaji S, Suzuki R, Kodera Y, Miyawaki S, Asou N, Kuriyama K, Yagasaki F, Shimazaki C, Akiyama H, Nishimura M, Motoji T, Shinagawa K, Takeshita A, Ueda R, Kinoshita T, Emi N, Naoe T.

Blood. 2005 Oct 15;106(8):2854-61. Epub 2005 Jun 30.

16.

Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias.

Falini B, Nicoletti I, Bolli N, Martelli MP, Liso A, Gorello P, Mandelli F, Mecucci C, Martelli MF.

Haematologica. 2007 Apr;92(4):519-32. Review.

17.

Prognostic significance of FLT3 internal tandem duplication and NPM1 mutations in acute myeloid leukemia in an unselected patient population.

Suzuki R, Onizuka M, Kojima M, Shimada M, Okamura K, Fukagawa S, Tsuboi K, Kikuchi A, Kobayashi H, Shintani A, Ogawa Y, Kawada H, Hotta T, Ando K.

Int J Hematol. 2007 Dec;86(5):422-8. doi: 10.1532/IJH97.07116.

PMID:
18192111
18.

Lack of nucleophosmin mutation in patients with myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities.

Shiseki M, Kitagawa Y, Wang YH, Yoshinaga K, Kondo T, Kuroiwa H, Okada M, Mori N, Motoji T.

Leuk Lymphoma. 2007 Nov;48(11):2141-4.

PMID:
17990177
19.

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.

Schlenk RF, Döhner K, Krauter J, Fröhling S, Corbacioglu A, Bullinger L, Habdank M, Späth D, Morgan M, Benner A, Schlegelberger B, Heil G, Ganser A, Döhner H; German-Austrian Acute Myeloid Leukemia Study Group.

N Engl J Med. 2008 May 1;358(18):1909-18. doi: 10.1056/NEJMoa074306.

20.

Detection of NPM1 exon 12 mutations and FLT3 - internal tandem duplications by high resolution melting analysis in normal karyotype acute myeloid leukemia.

Tan AY, Westerman DA, Carney DA, Seymour JF, Juneja S, Dobrovic A.

J Hematol Oncol. 2008 Jul 29;1:10. doi: 10.1186/1756-8722-1-10.

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