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Items: 1 to 20 of 151

1.

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I.

Schmidt A, Schwerd T, Hamm W, Hellmuth JC, Cui S, Wenzel M, Hoffmann FS, Michallet MC, Besch R, Hopfner KP, Endres S, Rothenfusser S.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12067-72. doi: 10.1073/pnas.0900971106. Epub 2009 Jul 2.

2.

Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity.

Gee P, Chua PK, Gevorkyan J, Klumpp K, Najera I, Swinney DC, Deval J.

J Biol Chem. 2008 Apr 4;283(14):9488-96. doi: 10.1074/jbc.M706777200. Epub 2008 Feb 11.

3.

5'-Triphosphate RNA is the ligand for RIG-I.

Hornung V, Ellegast J, Kim S, Brzózka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G.

Science. 2006 Nov 10;314(5801):994-7. Epub 2006 Oct 12.

4.

Approaching the RNA ligand for RIG-I?

Schlee M, Hartmann E, Coch C, Wimmenauer V, Janke M, Barchet W, Hartmann G.

Immunol Rev. 2009 Jan;227(1):66-74. doi: 10.1111/j.1600-065X.2008.00724.x. Review.

PMID:
19120476
5.

EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN.

Samanta M, Iwakiri D, Kanda T, Imaizumi T, Takada K.

EMBO J. 2006 Sep 20;25(18):4207-14. Epub 2006 Aug 31.

6.

Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.

Kalali BN, Köllisch G, Mages J, Müller T, Bauer S, Wagner H, Ring J, Lang R, Mempel M, Ollert M.

J Immunol. 2008 Aug 15;181(4):2694-704.

7.

Cutting Edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells.

Le Goffic R, Pothlichet J, Vitour D, Fujita T, Meurs E, Chignard M, Si-Tahar M.

J Immunol. 2007 Mar 15;178(6):3368-72.

8.

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I.

Cui S, Eisenächer K, Kirchhofer A, Brzózka K, Lammens A, Lammens K, Fujita T, Conzelmann KK, Krug A, Hopfner KP.

Mol Cell. 2008 Feb 1;29(2):169-79. doi: 10.1016/j.molcel.2007.10.032.

9.

RIG-I ATPase activity and discrimination of self-RNA versus non-self-RNA.

Anchisi S, Guerra J, Garcin D.

MBio. 2015 Mar 3;6(2):e02349. doi: 10.1128/mBio.02349-14.

10.

Activation of innate immune defense mechanisms by signaling through RIG-I/IPS-1 in intestinal epithelial cells.

Hirata Y, Broquet AH, Menchén L, Kagnoff MF.

J Immunol. 2007 Oct 15;179(8):5425-32.

11.

Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.

Myong S, Cui S, Cornish PV, Kirchhofer A, Gack MU, Jung JU, Hopfner KP, Ha T.

Science. 2009 Feb 20;323(5917):1070-4. doi: 10.1126/science.1168352. Epub 2009 Jan 1.

12.

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates.

Goubau D, Schlee M, Deddouche S, Pruijssers AJ, Zillinger T, Goldeck M, Schuberth C, Van der Veen AG, Fujimura T, Rehwinkel J, Iskarpatyoti JA, Barchet W, Ludwig J, Dermody TS, Hartmann G, Reis e Sousa C.

Nature. 2014 Oct 16;514(7522):372-5. doi: 10.1038/nature13590. Epub 2014 Aug 10.

13.

Toll-like receptor and RIG-I-like receptor signaling.

Kawai T, Akira S.

Ann N Y Acad Sci. 2008 Nov;1143:1-20. doi: 10.1196/annals.1443.020. Review.

PMID:
19076341
14.

Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response.

Plumet S, Herschke F, Bourhis JM, Valentin H, Longhi S, Gerlier D.

PLoS One. 2007 Mar 14;2(3):e279.

15.

Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells.

Besch R, Poeck H, Hohenauer T, Senft D, Häcker G, Berking C, Hornung V, Endres S, Ruzicka T, Rothenfusser S, Hartmann G.

J Clin Invest. 2009 Aug;119(8):2399-411. doi: 10.1172/JCI37155. Epub 2009 Jul 20.

16.

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.

Kowalinski E, Lunardi T, McCarthy AA, Louber J, Brunel J, Grigorov B, Gerlier D, Cusack S.

Cell. 2011 Oct 14;147(2):423-35. doi: 10.1016/j.cell.2011.09.039.

17.

The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.

Pippig DA, Hellmuth JC, Cui S, Kirchhofer A, Lammens K, Lammens A, Schmidt A, Rothenfusser S, Hopfner KP.

Nucleic Acids Res. 2009 Apr;37(6):2014-25. doi: 10.1093/nar/gkp059. Epub 2009 Feb 10.

18.

Vaccinia virus subverts a mitochondrial antiviral signaling protein-dependent innate immune response in keratinocytes through its double-stranded RNA binding protein, E3.

Deng L, Dai P, Parikh T, Cao H, Bhoj V, Sun Q, Chen Z, Merghoub T, Houghton A, Shuman S.

J Virol. 2008 Nov;82(21):10735-46. doi: 10.1128/JVI.01305-08. Epub 2008 Aug 20.

19.

Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I.

Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB.

MBio. 2015 Oct 6;6(5):e01265-15. doi: 10.1128/mBio.01265-15.

20.

Origin and evolution of the RIG-I like RNA helicase gene family.

Zou J, Chang M, Nie P, Secombes CJ.

BMC Evol Biol. 2009 Apr 28;9:85. doi: 10.1186/1471-2148-9-85.

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