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Items: 1 to 20 of 140

1.

Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation.

Lin BC, Suzawa M, Blind RD, Tobias SC, Bulun SE, Scanlan TS, Ingraham HA.

Cancer Res. 2009 Jul 1;69(13):5415-23. doi: 10.1158/0008-5472.CAN-08-1622. Epub 2009 Jun 23.

2.

Estradiol and tamoxifen induce cell migration through GPR30 and activation of focal adhesion kinase (FAK) in endometrial cancers with low or without nuclear estrogen receptor α (ERα).

Tsai CL, Wu HM, Lin CY, Lin YJ, Chao A, Wang TH, Hsueh S, Lai CH, Wang HS.

PLoS One. 2013 Sep 9;8(9):e72999. doi: 10.1371/journal.pone.0072999. eCollection 2013.

3.

The G protein-coupled receptor GPR30 mediates the nontranscriptional effect of estrogen on the activation of PI3K/Akt pathway in endometrial cancer cells.

Ge X, Guo R, Qiao Y, Zhang Y, Lei J, Wang X, Li L, Hu D.

Int J Gynecol Cancer. 2013 Jan;23(1):52-9. doi: 10.1097/IGC.0b013e31827912b8.

PMID:
23235274
5.

Nuclear estrogen receptor-mediated Notch signaling and GPR30-mediated PI3K/AKT signaling in the regulation of endometrial cancer cell proliferation.

Wei Y, Zhang Z, Liao H, Wu L, Wu X, Zhou D, Xi X, Zhu Y, Feng Y.

Oncol Rep. 2012 Feb;27(2):504-10. doi: 10.3892/or.2011.1536. Epub 2011 Nov 8.

PMID:
22075757
6.

The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells.

Vivacqua A, Bonofiglio D, Recchia AG, Musti AM, Picard D, Andò S, Maggiolini M.

Mol Endocrinol. 2006 Mar;20(3):631-46. Epub 2005 Oct 20.

PMID:
16239258
8.

The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.

Ariazi EA, Brailoiu E, Yerrum S, Shupp HA, Slifker MJ, Cunliffe HE, Black MA, Donato AL, Arterburn JB, Oprea TI, Prossnitz ER, Dun NJ, Jordan VC.

Cancer Res. 2010 Feb 1;70(3):1184-94. doi: 10.1158/0008-5472.CAN-09-3068. Epub 2010 Jan 19.

9.

G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.

Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A, Oprea TI, Prossnitz ER, Musti AM, Andò S, Maggiolini M.

Cancer Res. 2007 Feb 15;67(4):1859-66.

10.

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.

Lappano R, Santolla MF, Pupo M, Sinicropi MS, Caruso A, Rosano C, Maggiolini M.

Breast Cancer Res. 2012 Jan 17;14(1):R12.

11.

Estrogenic transmembrane receptor of GPR30 mediates invasion and carcinogenesis by endometrial cancer cell line RL95-2.

He YY, Du GQ, Cai B, Yan Q, Zhou L, Chen XY, Lu W, Yang YX, Wan XP.

J Cancer Res Clin Oncol. 2012 May;138(5):775-83. doi: 10.1007/s00432-011-1133-7. Epub 2012 Jan 24.

PMID:
22270964
12.

Regulation of estrogen target genes and growth by selective estrogen-receptor modulators in endometrial cancer cells.

Dardes RC, Schafer JM, Pearce ST, Osipo C, Chen B, Jordan VC.

Gynecol Oncol. 2002 Jun;85(3):498-506.

PMID:
12051881
13.

Estrogen receptor-mediated effects of tamoxifen on human endometrial cancer cells.

Sakamoto T, Eguchi H, Omoto Y, Ayabe T, Mori H, Hayashi S.

Mol Cell Endocrinol. 2002 Jun 28;192(1-2):93-104.

PMID:
12088871
14.

G protein-coupled receptor 30 in tumor development.

Wang D, Hu L, Zhang G, Zhang L, Chen C.

Endocrine. 2010 Aug;38(1):29-37. doi: 10.1007/s12020-010-9363-z. Epub 2010 Jul 8. Review.

PMID:
20960099
15.

GPER Mediates Non-Genomic Effects of Estrogen.

Pupo M, Maggiolini M, Musti AM.

Methods Mol Biol. 2016;1366:471-88. doi: 10.1007/978-1-4939-3127-9_37.

PMID:
26585158
16.

Two novel GPER agonists induce gene expression changes and growth effects in cancer cells.

Lappano R, Rosano C, Santolla MF, Pupo M, De Francesco EM, De Marco P, Ponassi M, Spallarossa A, Ranise A, Maggiolini M.

Curr Cancer Drug Targets. 2012 Jun;12(5):531-42.

PMID:
22414008
17.

The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

Maggiolini M, Vivacqua A, Fasanella G, Recchia AG, Sisci D, Pezzi V, Montanaro D, Musti AM, Picard D, Andò S.

J Biol Chem. 2004 Jun 25;279(26):27008-16. Epub 2004 Apr 16.

19.

Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER.

Zekas E, Prossnitz ER.

BMC Cancer. 2015 Oct 15;15:702. doi: 10.1186/s12885-015-1699-6.

20.

MAP kinase/estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance.

Atanaskova N, Keshamouni VG, Krueger JS, Schwartz JA, Miller F, Reddy KB.

Oncogene. 2002 Jun 6;21(25):4000-8.

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