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Results: 1 to 20 of 125

1.

Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation.

Wu HM, Tzeng NS, Qian L, Wei SJ, Hu X, Chen SH, Rawls SM, Flood P, Hong JS, Lu RB.

Neuropsychopharmacology. 2009 Sep;34(10):2344-57. doi: 10.1038/npp.2009.64. Epub 2009 Jun 17.

PMID:
19536110
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.

Zhang W, Qin L, Wang T, Wei SJ, Gao HM, Liu J, Wilson B, Liu B, Zhang W, Kim HC, Hong JS.

FASEB J. 2005 Mar;19(3):395-7. Epub 2004 Dec 13.

PMID:
15596482
[PubMed - indexed for MEDLINE]
Free Article
3.

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.

J Neuroinflammation. 2008 May 28;5:21. doi: 10.1186/1742-2094-5-21.

PMID:
18507839
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.

Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM.

J Neuroinflammation. 2007 Sep 19;4:23.

PMID:
17880684
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage.

Li G, Cui G, Tzeng NS, Wei SJ, Wang T, Block ML, Hong JS.

FASEB J. 2005 Apr;19(6):489-96.

PMID:
15790998
[PubMed - indexed for MEDLINE]
Free Article
6.

Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia.

Peng GS, Li G, Tzeng NS, Chen PS, Chuang DM, Hsu YD, Yang S, Hong JS.

Brain Res Mol Brain Res. 2005 Mar 24;134(1):162-9. Epub 2004 Nov 25.

PMID:
15790540
[PubMed - indexed for MEDLINE]
7.

The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.

Tran TA, McCoy MK, Sporn MB, Tansey MG.

J Neuroinflammation. 2008 May 12;5:14. doi: 10.1186/1742-2094-5-14.

PMID:
18474101
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

Liu Y, Qin L, Li G, Zhang W, An L, Liu B, Hong JS.

J Pharmacol Exp Ther. 2003 Apr;305(1):212-8.

PMID:
12649371
[PubMed - indexed for MEDLINE]
Free Article
9.

Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes.

Chen PS, Peng GS, Li G, Yang S, Wu X, Wang CC, Wilson B, Lu RB, Gean PW, Chuang DM, Hong JS.

Mol Psychiatry. 2006 Dec;11(12):1116-25. Epub 2006 Sep 12.

PMID:
16969367
[PubMed - indexed for MEDLINE]
10.

Amantadine protects dopamine neurons by a dual action: reducing activation of microglia and inducing expression of GDNF in astroglia [corrected].

Ossola B, Schendzielorz N, Chen SH, Bird GS, Tuominen RK, Männistö PT, Hong JS.

Neuropharmacology. 2011 Sep;61(4):574-82. doi: 10.1016/j.neuropharm.2011.04.030. Epub 2011 May 11. Erratum in: Neuropharmacology. 2012 Feb;62(2):1162.

PMID:
21586298
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Microglia enhance manganese chloride-induced dopaminergic neurodegeneration: role of free radical generation.

Zhang P, Wong TA, Lokuta KM, Turner DE, Vujisic K, Liu B.

Exp Neurol. 2009 May;217(1):219-30. doi: 10.1016/j.expneurol.2009.02.013. Epub 2009 Mar 5.

PMID:
19268665
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Catalpol protects dopaminergic neurons from LPS-induced neurotoxicity in mesencephalic neuron-glia cultures.

Tian YY, An LJ, Jiang L, Duan YL, Chen J, Jiang B.

Life Sci. 2006 Dec 23;80(3):193-9. Epub 2006 Sep 20.

PMID:
17049947
[PubMed - indexed for MEDLINE]
13.

Femtomolar concentrations of dynorphins protect rat mesencephalic dopaminergic neurons against inflammatory damage.

Liu B, Qin L, Yang SN, Wilson BC, Liu Y, Hong JS.

J Pharmacol Exp Ther. 2001 Sep;298(3):1133-41.

PMID:
11504811
[PubMed - indexed for MEDLINE]
Free Article
14.

Involvement of proinflammatory factors, apoptosis, caspase-3 activation and Ca2+ disturbance in microglia activation-mediated dopaminergic cell degeneration.

Wang X, Chen S, Ma G, Ye M, Lu G.

Mech Ageing Dev. 2005 Dec;126(12):1241-54. Epub 2005 Aug 19.

PMID:
16112714
[PubMed - indexed for MEDLINE]
15.

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons.

Wu X, Chen PS, Dallas S, Wilson B, Block ML, Wang CC, Kinyamu H, Lu N, Gao X, Leng Y, Chuang DM, Zhang W, Lu RB, Hong JS.

Int J Neuropsychopharmacol. 2008 Dec;11(8):1123-34. doi: 10.1017/S1461145708009024. Epub 2008 Jul 9.

PMID:
18611290
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS.

J Biol Chem. 2004 Jan 9;279(2):1415-21. Epub 2003 Oct 24.

PMID:
14578353
[PubMed - indexed for MEDLINE]
Free Article
17.

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage.

Chen SH, Wu HM, Ossola B, Schendzielorz N, Wilson BC, Chu CH, Chen SL, Wang Q, Zhang D, Qian L, Li X, Hong JS, Lu RB.

Br J Pharmacol. 2012 Jan;165(2):494-505. doi: 10.1111/j.1476-5381.2011.01575.x.

PMID:
21726209
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity.

Chen PS, Wang CC, Bortner CD, Peng GS, Wu X, Pang H, Lu RB, Gean PW, Chuang DM, Hong JS.

Neuroscience. 2007 Oct 12;149(1):203-12. Epub 2007 Jul 28.

PMID:
17850978
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Astrocyte-derived GDNF is a potent inhibitor of microglial activation.

Rocha SM, Cristovão AC, Campos FL, Fonseca CP, Baltazar G.

Neurobiol Dis. 2012 Sep;47(3):407-15. doi: 10.1016/j.nbd.2012.04.014. Epub 2012 May 3.

PMID:
22579772
[PubMed - indexed for MEDLINE]
20.

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