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Items: 1 to 20 of 187

1.

Skeletal muscle AMP-activated protein kinase is essential for the metabolic response to exercise in vivo.

Lee-Young RS, Griffee SR, Lynes SE, Bracy DP, Ayala JE, McGuinness OP, Wasserman DH.

J Biol Chem. 2009 Sep 4;284(36):23925-34. doi: 10.1074/jbc.M109.021048. Epub 2009 Jun 12.

2.

Obesity impairs skeletal muscle AMPK signaling during exercise: role of AMPKα2 in the regulation of exercise capacity in vivo.

Lee-Young RS, Ayala JE, Fueger PT, Mayes WH, Kang L, Wasserman DH.

Int J Obes (Lond). 2011 Jul;35(7):982-9. doi: 10.1038/ijo.2010.220. Epub 2010 Nov 16.

3.

Genetic impairment of AMPKalpha2 signaling does not reduce muscle glucose uptake during treadmill exercise in mice.

Maarbjerg SJ, Jørgensen SB, Rose AJ, Jeppesen J, Jensen TE, Treebak JT, Birk JB, Schjerling P, Wojtaszewski JF, Richter EA.

Am J Physiol Endocrinol Metab. 2009 Oct;297(4):E924-34. doi: 10.1152/ajpendo.90653.2008. Epub 2009 Aug 4.

4.

Endothelial nitric oxide synthase is central to skeletal muscle metabolic regulation and enzymatic signaling during exercise in vivo.

Lee-Young RS, Ayala JE, Hunley CF, James FD, Bracy DP, Kang L, Wasserman DH.

Am J Physiol Regul Integr Comp Physiol. 2010 May;298(5):R1399-408. doi: 10.1152/ajpregu.00004.2010. Epub 2010 Mar 3.

5.

Alpha2-AMPK activity is not essential for an increase in fatty acid oxidation during low-intensity exercise.

Miura S, Kai Y, Kamei Y, Bruce CR, Kubota N, Febbraio MA, Kadowaki T, Ezaki O.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E47-55. doi: 10.1152/ajpendo.90690.2008. Epub 2008 Oct 21.

6.

Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.

Steinberg GR, O'Neill HM, Dzamko NL, Galic S, Naim T, Koopman R, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott JW, Koentgen F, Lynch GS, Watt MJ, van Denderen BJ, Campbell DJ, Kemp BE.

J Biol Chem. 2010 Nov 26;285(48):37198-209. doi: 10.1074/jbc.M110.102434. Epub 2010 Sep 20.

7.

Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

Jørgensen SB, Wojtaszewski JF, Viollet B, Andreelli F, Birk JB, Hellsten Y, Schjerling P, Vaulont S, Neufer PD, Richter EA, Pilegaard H.

FASEB J. 2005 Jul;19(9):1146-8. Epub 2005 May 5.

8.

AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.

O'Neill HM, Maarbjerg SJ, Crane JD, Jeppesen J, Jørgensen SB, Schertzer JD, Shyroka O, Kiens B, van Denderen BJ, Tarnopolsky MA, Kemp BE, Richter EA, Steinberg GR.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16092-7. doi: 10.1073/pnas.1105062108. Epub 2011 Sep 6.

9.

Role of AMP-activated protein kinase in exercise capacity, whole body glucose homeostasis, and glucose transport in skeletal muscle -insight from analysis of a transgenic mouse model-.

Fujii N, Seifert MM, Kane EM, Peter LE, Ho RC, Winstead S, Hirshman MF, Goodyear LJ.

Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S92-8. Epub 2007 Apr 23.

PMID:
17452058
10.

α2 isoform-specific activation of 5'adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal muscle.

Nakano M, Hamada T, Hayashi T, Yonemitsu S, Miyamoto L, Toyoda T, Tanaka S, Masuzaki H, Ebihara K, Ogawa Y, Hosoda K, Inoue G, Yoshimasa Y, Otaka A, Fushiki T, Nakao K.

Metabolism. 2006 Mar;55(3):300-8.

PMID:
16483872
11.

AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle.

Lee-Young RS, Bonner JS, Mayes WH, Iwueke I, Barrick BA, Hasenour CM, Kang L, Wasserman DH.

Diabetologia. 2013 Mar;56(3):608-17. doi: 10.1007/s00125-012-2787-7. Epub 2012 Dec 8.

12.

AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise.

Zwetsloot KA, Westerkamp LM, Holmes BF, Gavin TP.

J Physiol. 2008 Dec 15;586(Pt 24):6021-35. doi: 10.1113/jphysiol.2008.159871. Epub 2008 Oct 27.

13.

Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm.

Miura S, Kai Y, Tadaishi M, Tokutake Y, Sakamoto K, Bruce CR, Febbraio MA, Kita K, Chohnan S, Ezaki O.

Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E213-29. doi: 10.1152/ajpendo.00114.2013. Epub 2013 May 21.

14.

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity.

Lantier L, Fentz J, Mounier R, Leclerc J, Treebak JT, Pehmøller C, Sanz N, Sakakibara I, Saint-Amand E, Rimbaud S, Maire P, Marette A, Ventura-Clapier R, Ferry A, Wojtaszewski JF, Foretz M, Viollet B.

FASEB J. 2014 Jul;28(7):3211-24. doi: 10.1096/fj.14-250449. Epub 2014 Mar 20.

15.

Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift.

Röckl KS, Hirshman MF, Brandauer J, Fujii N, Witters LA, Goodyear LJ.

Diabetes. 2007 Aug;56(8):2062-9. Epub 2007 May 18.

16.

Lack of AMPKalpha2 enhances pyruvate dehydrogenase activity during exercise.

Klein DK, Pilegaard H, Treebak JT, Jensen TE, Viollet B, Schjerling P, Wojtaszewski JF.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1242-9. Epub 2007 Aug 21.

17.

Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase.

Fryer LG, Hajduch E, Rencurel F, Salt IP, Hundal HS, Hardie DG, Carling D.

Diabetes. 2000 Dec;49(12):1978-85.

PMID:
11117997
18.

Control of microvascular PO₂ kinetics following onset of muscle contractions: role for AMPK.

Kano Y, Poole DC, Sudo M, Hirachi T, Miura S, Ezaki O.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1350-7. doi: 10.1152/ajpregu.00294.2011. Epub 2011 Aug 17.

19.

The effects of age and muscle contraction on AMPK activity and heterotrimer composition.

Hardman SE, Hall DE, Cabrera AJ, Hancock CR, Thomson DM.

Exp Gerontol. 2014 Jul;55:120-8. doi: 10.1016/j.exger.2014.04.007. Epub 2014 Apr 18.

20.

Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice.

Kristensen JM, Larsen S, Helge JW, Dela F, Wojtaszewski JF.

PLoS One. 2013;8(1):e53533. doi: 10.1371/journal.pone.0053533. Epub 2013 Jan 14.

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