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Results: 1 to 20 of 95

1.

Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies.

O'Brien N, Jones ST, Williams DG, Cunningham HB, Moreno K, Visentin B, Gentile A, Vekich J, Shestowsky W, Hiraiwa M, Matteo R, Cavalli A, Grotjahn D, Grant M, Hansen G, Campbell MA, Sabbadini R.

J Lipid Res. 2009 Nov;50(11):2245-57. doi: 10.1194/jlr.M900048-JLR200. Epub 2009 Jun 9.

PMID:
19509417
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization.

Caballero S, Swaney J, Moreno K, Afzal A, Kielczewski J, Stoller G, Cavalli A, Garland W, Hansen G, Sabbadini R, Grant MB.

Exp Eye Res. 2009 Mar;88(3):367-77. doi: 10.1016/j.exer.2008.07.012. Epub 2008 Aug 6.

PMID:
18723015
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen.

Wojciak JM, Zhu N, Schuerenberg KT, Moreno K, Shestowsky WS, Hiraiwa M, Sabbadini R, Huxford T.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17717-22. doi: 10.1073/pnas.0906153106. Epub 2009 Oct 7. Erratum in: Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2723. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18873.

PMID:
19815502
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.

Sabbadini RA.

Br J Pharmacol. 2011 Mar;162(6):1225-38. doi: 10.1111/j.1476-5381.2010.01118.x. Review.

PMID:
21091645
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages.

Visentin B, Vekich JA, Sibbald BJ, Cavalli AL, Moreno KM, Matteo RG, Garland WA, Lu Y, Yu S, Hall HS, Kundra V, Mills GB, Sabbadini RA.

Cancer Cell. 2006 Mar;9(3):225-38.

PMID:
16530706
[PubMed - indexed for MEDLINE]
Free Article
6.

Targeting sphingosine-1-phosphate: a novel avenue for cancer therapeutics.

Milstien S, Spiegel S.

Cancer Cell. 2006 Mar;9(3):148-50. Review.

PMID:
16530698
[PubMed - indexed for MEDLINE]
Free Article
7.

Local inactivation of sphingosine 1-phosphate in lymph nodes induces lymphopenia.

Sensken SC, Nagarajan M, Bode C, Gräler MH.

J Immunol. 2011 Mar 15;186(6):3432-40. doi: 10.4049/jimmunol.1002169. Epub 2011 Feb 2.

PMID:
21289303
[PubMed - indexed for MEDLINE]
Free Article
8.

Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor.

Dorsam G, Graeler MH, Seroogy C, Kong Y, Voice JK, Goetzl EJ.

J Immunol. 2003 Oct 1;171(7):3500-7.

PMID:
14500646
[PubMed - indexed for MEDLINE]
Free Article
9.

Blockade of sphingosine-1-phosphate reduces macrophage influx and retinal and choroidal neovascularization.

Xie B, Shen J, Dong A, Rashid A, Stoller G, Campochiaro PA.

J Cell Physiol. 2009 Jan;218(1):192-8. doi: 10.1002/jcp.21588.

PMID:
18781584
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts.

Gellings Lowe N, Swaney JS, Moreno KM, Sabbadini RA.

Cardiovasc Res. 2009 May 1;82(2):303-12. doi: 10.1093/cvr/cvp056. Epub 2009 Feb 19.

PMID:
19228708
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Targeting sphingosine-1-phosphate for cancer therapy.

Sabbadini RA.

Br J Cancer. 2006 Nov 6;95(9):1131-5. Epub 2006 Oct 3. Review.

PMID:
17024123
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.

Allende ML, Bektas M, Lee BG, Bonifacino E, Kang J, Tuymetova G, Chen W, Saba JD, Proia RL.

J Biol Chem. 2011 Mar 4;286(9):7348-58. doi: 10.1074/jbc.M110.171819. Epub 2010 Dec 20.

PMID:
21173151
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy?

Dai L, Xia P, Di W.

Cancer Invest. 2014 Mar;32(3):71-80. doi: 10.3109/07357907.2013.876646. Review.

PMID:
24499107
[PubMed - indexed for MEDLINE]
14.

Bioactive lipids S1P and C1P are prometastatic factors in human rhabdomyosarcoma, and their tissue levels increase in response to radio/chemotherapy.

Schneider G, Bryndza E, Abdel-Latif A, Ratajczak J, Maj M, Tarnowski M, Klyachkin YM, Houghton P, Morris AJ, Vater A, Klussmann S, Kucia M, Ratajczak MZ.

Mol Cancer Res. 2013 Jul;11(7):793-807. doi: 10.1158/1541-7786.MCR-12-0600. Epub 2013 Apr 24.

PMID:
23615526
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice.

Nofer JR, Bot M, Brodde M, Taylor PJ, Salm P, Brinkmann V, van Berkel T, Assmann G, Biessen EA.

Circulation. 2007 Jan 30;115(4):501-8. Epub 2007 Jan 22.

PMID:
17242282
[PubMed - indexed for MEDLINE]
Free Article
16.

Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration.

Danieli-Betto D, Peron S, Germinario E, Zanin M, Sorci G, Franzoso S, Sandonà D, Betto R.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C550-8. doi: 10.1152/ajpcell.00072.2009. Epub 2009 Dec 30.

PMID:
20042733
[PubMed - indexed for MEDLINE]
Free Article
17.

The functional roles of S1P in immunity.

Hisano Y, Nishi T, Kawahara A.

J Biochem. 2012 Oct;152(4):305-11. Epub 2012 Aug 24. Review.

PMID:
22923732
[PubMed - indexed for MEDLINE]
18.

A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders.

Huwiler A, Bourquin F, Kotelevets N, Pastukhov O, Capitani G, Grütter MG, Zangemeister-Wittke U.

PLoS One. 2011;6(8):e22436. doi: 10.1371/journal.pone.0022436. Epub 2011 Aug 1.

PMID:
21829623
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Gαq coupling.

Kim ES, Kim JS, Kim SG, Hwang S, Lee CH, Moon A.

J Cell Sci. 2011 Jul 1;124(Pt 13):2220-30. doi: 10.1242/jcs.076794. Epub 2011 Jun 7.

PMID:
21652634
[PubMed - indexed for MEDLINE]
Free Article
20.

Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow.

Maeda Y, Seki N, Sato N, Sugahara K, Chiba K.

Int Immunol. 2010 Jun;22(6):515-25. doi: 10.1093/intimm/dxq036. Epub 2010 May 23.

PMID:
20497959
[PubMed - indexed for MEDLINE]
Free Article

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