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Results: 1 to 20 of 1494

1.

Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis.

Sun R, Skeiky YA, Izzo A, Dheenadhayalan V, Imam Z, Penn E, Stagliano K, Haddock S, Mueller S, Fulkerson J, Scanga C, Grover A, Derrick SC, Morris S, Hone DM, Horwitz MA, Kaufmann SH, Sadoff JC.

Vaccine. 2009 Jul 16;27(33):4412-23. doi: 10.1016/j.vaccine.2009.05.048. Epub 2009 Jun 2.

PMID:
19500523
[PubMed - indexed for MEDLINE]
2.

[Novel vaccines against M. tuberculosis].

Okada M.

Kekkaku. 2006 Dec;81(12):745-51. Review. Japanese.

PMID:
17240920
[PubMed - indexed for MEDLINE]
3.

Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-gamma producing T-cells.

Badell E, Nicolle F, Clark S, Majlessi L, Boudou F, Martino A, Castello-Branco L, Leclerc C, Lewis DJ, Marsh PD, Gicquel B, Winter N.

Vaccine. 2009 Jan 1;27(1):28-37. doi: 10.1016/j.vaccine.2008.10.034. Epub 2008 Oct 31.

PMID:
18977269
[PubMed - indexed for MEDLINE]
4.
5.

Recombinant BCG coexpressing Ag85B, CFP10, and interleukin-12 induces multifunctional Th1 and memory T cells in mice.

Lin CW, Su IJ, Chang JR, Chen YY, Lu JJ, Dou HY.

APMIS. 2012 Jan;120(1):72-82. doi: 10.1111/j.1600-0463.2011.02815.x. Epub 2011 Oct 6.

PMID:
22151310
[PubMed - indexed for MEDLINE]
6.

Novel recombinant BCG coexpressing Ag85B, ESAT-6 and mouse TNF-alpha induces significantly enhanced cellular immune and antibody responses in C57BL/6 mice.

Shen H, Wang C, Yang E, Xu Y, Liu W, Yan J, Wang F, Wang H.

Microbiol Immunol. 2010 Aug;54(8):435-41. doi: 10.1111/j.1348-0421.2010.00232.x.

PMID:
20646207
[PubMed - indexed for MEDLINE]
7.

Immunological memory transferred with CD4 T cells specific for tuberculosis antigens Ag85B-TB10.4: persisting antigen enhances protection.

Duffy D, Dawoodji A, Agger EM, Andersen P, Westermann J, Bell EB.

PLoS One. 2009 Dec 14;4(12):e8272. doi: 10.1371/journal.pone.0008272.

PMID:
20011592
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Modulation of host immune responses by overexpression of immunodominant antigens of Mycobacterium tuberculosis in bacille Calmette-Guérin.

Rao V, Dhar N, Tyagi AK.

Scand J Immunol. 2003 Oct;58(4):449-61.

PMID:
14507310
[PubMed - indexed for MEDLINE]
9.

Immune responses and protective efficacy induced by 85B antigen and early secreted antigenic target-6 kDa antigen fusion protein secreted by recombinant bacille Calmette-Guérin.

Shi C, Wang X, Zhang H, Xu Z, Li Y, Yuan L.

Acta Biochim Biophys Sin (Shanghai). 2007 Apr;39(4):290-6.

PMID:
17417685
[PubMed - indexed for MEDLINE]
Free Article
10.

Immunogenicity and efficacy of a tuberculosis DNA vaccine encoding the components of the secreted antigen 85 complex.

Lozes E, Huygen K, Content J, Denis O, Montgomery DL, Yawman AM, Vandenbussche P, Van Vooren JP, Drowart A, Ulmer JB, Liu MA.

Vaccine. 1997 Jun;15(8):830-3.

PMID:
9234526
[PubMed - indexed for MEDLINE]
11.

Immunogenicity and protective efficacy of a novel recombinant BCG strain overexpressing antigens Ag85A and Ag85B.

Wang C, Fu R, Chen Z, Tan K, Chen L, Teng X, Lu J, Shi C, Fan X.

Clin Dev Immunol. 2012;2012:563838. doi: 10.1155/2012/563838. Epub 2012 Apr 18.

PMID:
22570667
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein.

Shi C, Chen L, Chen Z, Zhang Y, Zhou Z, Lu J, Fu R, Wang C, Fang Z, Fan X.

Vaccine. 2010 Jul 19;28(32):5237-44. doi: 10.1016/j.vaccine.2010.05.063. Epub 2010 Jun 9.

PMID:
20538090
[PubMed - indexed for MEDLINE]
13.
14.

Evaluation of a new recombinant BCG which contains mycobacterial antigen ag85B-mpt64(190-198)-mtb8.4 in C57/BL6 mice.

Qie YQ, Wang JL, Zhu BD, Xu Y, Wang QZ, Chen JZ, Wang HH.

Scand J Immunol. 2008 Feb;67(2):133-9. doi: 10.1111/j.1365-3083.2007.02048.x.

PMID:
18201368
[PubMed - indexed for MEDLINE]
15.

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens.

Brodin P, Majlessi L, Brosch R, Smith D, Bancroft G, Clark S, Williams A, Leclerc C, Cole ST.

J Infect Dis. 2004 Jul 1;190(1):115-22. Epub 2004 Jun 4.

PMID:
15195250
[PubMed - indexed for MEDLINE]
Free Article
16.

Novel recombinant BCG coexpressing Ag85B, ESAT-6 and Rv2608 elicits significantly enhanced cellular immune and antibody responses in C57BL/6 mice.

Lu Y, Xu Y, Yang E, Wang C, Wang H, Shen H.

Scand J Immunol. 2012 Sep;76(3):271-7. doi: 10.1111/j.1365-3083.2012.02726.x.

PMID:
22671973
[PubMed - indexed for MEDLINE]
17.

Vaccination with the T cell antigen Mtb 8.4 protects against challenge with Mycobacterium tuberculosis.

Coler RN, Campos-Neto A, Ovendale P, Day FH, Fling SP, Zhu L, Serbina N, Flynn JL, Reed SG, Alderson MR.

J Immunol. 2001 May 15;166(10):6227-35.

PMID:
11342645
[PubMed - indexed for MEDLINE]
Free Article
18.

Efficacy of recombinant bacille Calmette-Guérin vaccine secreting interleukin-15/antigen 85B fusion protein in providing protection against Mycobacterium tuberculosis.

Tang C, Yamada H, Shibata K, Maeda N, Yoshida S, Wajjwalku W, Ohara N, Yamada T, Kinoshita T, Yoshikai Y.

J Infect Dis. 2008 May 1;197(9):1263-74. doi: 10.1086/586902.

PMID:
18422438
[PubMed - indexed for MEDLINE]
Free Article
19.

Fusion protein Ag85B-MPT64(190-198)-Mtb8.4 has higher immunogenicity than Ag85B with capacity to boost BCG-primed immunity against Mycobacterium tuberculosis in mice.

Luo Y, Wang B, Hu L, Yu H, Da Z, Jiang W, Song N, Qie Y, Wang H, Tang Z, Xian Q, Zhang Y, Zhu B.

Vaccine. 2009 Oct 19;27(44):6179-85. doi: 10.1016/j.vaccine.2009.08.018. Epub 2009 Aug 25.

PMID:
19712772
[PubMed - indexed for MEDLINE]
20.

Immune responses and protective efficacy of the gene vaccine expressing Ag85B and ESAT6 fusion protein from Mycobacterium tuberculosis.

Chang-hong S, Xiao-wu W, Hai Z, Ting-fen Z, Li-Mei W, Zhi-kai X.

DNA Cell Biol. 2008 Apr;27(4):199-207. doi: 10.1089/dna.2007.0648.

PMID:
18163878
[PubMed - indexed for MEDLINE]
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