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Results: 1 to 20 of 100

1.

Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte.

Sonne SB, Almstrup K, Dalgaard M, Juncker AS, Edsgard D, Ruban L, Harrison NJ, Schwager C, Abdollahi A, Huber PE, Brunak S, Gjerdrum LM, Moore HD, Andrews PW, Skakkebaek NE, Rajpert-De Meyts E, Leffers H.

Cancer Res. 2009 Jun 15;69(12):5241-50. doi: 10.1158/0008-5472.CAN-08-4554. Epub 2009 Jun 2.

PMID:
19491264
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours.

Hoei-Hansen CE, Almstrup K, Nielsen JE, Brask Sonne S, Graem N, Skakkebaek NE, Leffers H, Rajpert-De Meyts E.

Histopathology. 2005 Jul;47(1):48-56.

PMID:
15982323
[PubMed - indexed for MEDLINE]
3.

Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects.

Rajpert-De Meyts E.

Hum Reprod Update. 2006 May-Jun;12(3):303-23. Epub 2006 Mar 15. Review.

PMID:
16540528
[PubMed - indexed for MEDLINE]
Free Article
4.

The emerging phenotype of the testicular carcinoma in situ germ cell.

Rajpert-De Meyts E, Bartkova J, Samson M, Hoei-Hansen CE, Frydelund-Larsen L, Bartek J, Skakkebaek NE.

APMIS. 2003 Jan;111(1):267-78; discussion 278-9. Review.

PMID:
12752272
[PubMed - indexed for MEDLINE]
5.

AZFa protein DDX3Y is differentially expressed in human male germ cells during development and in testicular tumours: new evidence for phenotypic plasticity of germ cells.

Gueler B, Sonne SB, Zimmer J, Hilscher B, Hilscher W, Græm N, Rajpert-De Meyts E, Vogt PH.

Hum Reprod. 2012 Jun;27(6):1547-55. doi: 10.1093/humrep/des047. Epub 2012 Mar 30.

PMID:
22466863
[PubMed - indexed for MEDLINE]
Free Article
6.

From gonocytes to testicular cancer: the role of impaired gonadal development.

Rajpert-de Meyts E, Hoei-Hansen CE.

Ann N Y Acad Sci. 2007 Dec;1120:168-80. doi: 10.1196/annals.1411.013. Review.

PMID:
18184914
[PubMed - indexed for MEDLINE]
7.

MicroRNA expression profiling of carcinoma in situ cells of the testis.

Novotny GW, Belling KC, Bramsen JB, Nielsen JE, Bork-Jensen J, Almstrup K, Sonne SB, Kjems J, Rajpert-De Meyts E, Leffers H.

Endocr Relat Cancer. 2012 May 24;19(3):365-79. doi: 10.1530/ERC-11-0271. Print 2012 Jun.

PMID:
22420006
[PubMed - indexed for MEDLINE]
Free Article
8.

Differential developmental expression of transcription factors GATA-4 and GATA-6, their cofactor FOG-2 and downstream target genes in testicular carcinoma in situ and germ cell tumors.

Salonen J, Rajpert-De Meyts E, Mannisto S, Nielsen JE, Graem N, Toppari J, Heikinheimo M.

Eur J Endocrinol. 2010 Mar;162(3):625-31. doi: 10.1530/EJE-09-0734. Epub 2009 Dec 7.

PMID:
19969558
[PubMed - indexed for MEDLINE]
Free Article
9.

Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.

Hoei-Hansen CE, Nielsen JE, Almstrup K, Sonne SB, Graem N, Skakkebaek NE, Leffers H, Rajpert-De Meyts E.

Clin Cancer Res. 2004 Dec 15;10(24):8521-30.

PMID:
15623634
[PubMed - indexed for MEDLINE]
Free Article
10.

Alterations of the p53 tumor suppressor gene in carcinoma in situ of the testis.

Kuczyk MA, Serth J, Bokemeyer C, Jonassen J, Machtens S, Werner M, Jonas U.

Cancer. 1996 Nov 1;78(9):1958-66.

PMID:
8909317
[PubMed - indexed for MEDLINE]
11.

Dysregulation of the mitosis-meiosis switch in testicular carcinoma in situ.

Jørgensen A, Nielsen JE, Almstrup K, Toft BG, Petersen BL, Rajpert-De Meyts E.

J Pathol. 2013 Mar;229(4):588-98. doi: 10.1002/path.4154. Epub 2013 Feb 4.

PMID:
23303528
[PubMed - indexed for MEDLINE]
12.

Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ.

Almstrup K, Ottesen AM, Sonne SB, Hoei-Hansen CE, Leffers H, Rajpert-De Meyts E, Skakkebaek NE.

Cell Tissue Res. 2005 Oct;322(1):159-65. Epub 2005 Nov 3. Review.

PMID:
15846514
[PubMed - indexed for MEDLINE]
13.

Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling.

Almstrup K, Hoei-Hansen CE, Wirkner U, Blake J, Schwager C, Ansorge W, Nielsen JE, Skakkebaek NE, Rajpert-De Meyts E, Leffers H.

Cancer Res. 2004 Jul 15;64(14):4736-43.

PMID:
15256440
[PubMed - indexed for MEDLINE]
Free Article
14.

Identification of genes differentially expressed in testes containing carcinoma in situ.

Hoei-Hansen CE, Nielsen JE, Almstrup K, Hansen MA, Skakkebaek NE, Rajpert-DeMeyts E, Leffers H.

Mol Hum Reprod. 2004 Jun;10(6):423-31.

PMID:
15123780
[PubMed - indexed for MEDLINE]
Free Article
15.

Testicular dysgenesis syndrome and the origin of carcinoma in situ testis.

Sonne SB, Kristensen DM, Novotny GW, Olesen IA, Nielsen JE, Skakkebaek NE, Rajpert-De Meyts E, Leffers H.

Int J Androl. 2008 Apr;31(2):275-87. doi: 10.1111/j.1365-2605.2007.00855.x. Epub 2008 Jan 16. Review.

PMID:
18205797
[PubMed - indexed for MEDLINE]
16.

Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications.

de Jong J, Stoop H, Gillis AJ, van Gurp RJ, van de Geijn GJ, Boer Md, Hersmus R, Saunders PT, Anderson RA, Oosterhuis JW, Looijenga LH.

J Pathol. 2008 May;215(1):21-30. doi: 10.1002/path.2332.

PMID:
18348160
[PubMed - indexed for MEDLINE]
17.

Improved gene expression signature of testicular carcinoma in situ.

Almstrup K, Leffers H, Lothe RA, Skakkebaek NE, Sonne SB, Nielsen JE, Rajpert-De Meyts E, Skotheim RI.

Int J Androl. 2007 Aug;30(4):292-302; discussion 303. Epub 2007 May 7.

PMID:
17488342
[PubMed - indexed for MEDLINE]
18.

Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma.

Skakkebaek NE, Berthelsen JG, Giwercman A, Müller J.

Int J Androl. 1987 Feb;10(1):19-28.

PMID:
3034791
[PubMed - indexed for MEDLINE]
19.

Expression of FGFR3 during human testis development and in germ cell-derived tumours of young adults.

Ewen KA, Olesen IA, Winge SB, Nielsen AR, Nielsen JE, Graem N, Juul A, Rajpert-De Meyts E.

Int J Dev Biol. 2013;57(2-4):141-51. doi: 10.1387/ijdb.130022er.

PMID:
23784824
[PubMed - indexed for MEDLINE]
Free Article
20.

Clinical and biological significance of carcinoma in situ of the testis.

Jørgensen N, Müller J, Giwercman A, Skakkebaek NE.

Cancer Surv. 1990;9(2):287-302. Review.

PMID:
1964624
[PubMed - indexed for MEDLINE]
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