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Items: 1 to 20 of 67

1.

Functional screen of human MCM2-7 variant alleles for disease-causing potential.

Steere NA, Yamaguchi S, Andrews CA, Liachko I, Nakamura T, Shima N.

Mutat Res. 2009 Jun 18;666(1-2):74-8. doi: 10.1016/j.mrfmmm.2009.03.006. Epub 2009 Mar 27.

PMID:
19481678
2.

A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

Shima N, Alcaraz A, Liachko I, Buske TR, Andrews CA, Munroe RJ, Hartford SA, Tye BK, Schimenti JC.

Nat Genet. 2007 Jan;39(1):93-8. Epub 2006 Dec 3.

PMID:
17143284
3.

Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.

Chuang CH, Wallace MD, Abratte C, Southard T, Schimenti JC.

PLoS Genet. 2010 Sep 9;6(9):e1001110. doi: 10.1371/journal.pgen.1001110.

4.

ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes.

Stead BE, Sorbara CD, Brandl CJ, Davey MJ.

J Mol Biol. 2009 Aug 14;391(2):301-13. doi: 10.1016/j.jmb.2009.06.038. Epub 2009 Jun 21.

PMID:
19540846
5.

Constitutive association of Mcm2-3-5 proteins with chromatin in Entamoeba histolytica.

Das S, Mukherjee C, Sinha P, Lohia A.

Cell Microbiol. 2005 Feb;7(2):259-67.

PMID:
15659069
6.

Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells.

Chuang CH, Yang D, Bai G, Freeland A, Pruitt SC, Schimenti JC.

Nucleic Acids Res. 2012 Jun;40(11):4914-24. doi: 10.1093/nar/gks176. Epub 2012 Feb 22.

7.

Genetic screen for chromosome instability in mice: Mcm4 and breast cancer.

Shima N, Buske TR, Schimenti JC.

Cell Cycle. 2007 May 15;6(10):1135-40. Epub 2007 May 5.

PMID:
17495541
8.

A dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesis.

Bagley BN, Keane TM, Maklakova VI, Marshall JG, Lester RA, Cancel MM, Paulsen AR, Bendzick LE, Been RA, Kogan SC, Cormier RT, Kendziorski C, Adams DJ, Collier LS.

PLoS Genet. 2012;8(11):e1003034. doi: 10.1371/journal.pgen.1003034. Epub 2012 Nov 1.

9.

Two mcm3 mutations affect different steps in the initiation of DNA replication.

Lei M, Cheng IH, Roberts LA, McAlear MA, Tye BK.

J Biol Chem. 2002 Aug 23;277(34):30824-31. Epub 2002 Jun 11.

10.

Minichromosome maintenance protein 5 homologue in Caenorhabditis elegans plays essential role for postembryonic development.

Wang X, Suh C, Zhu Z, Fan Q.

Biochem Biophys Res Commun. 2007 Aug 10;359(4):965-71. Epub 2007 Jun 6.

PMID:
17568563
11.

Biochemical function of mouse minichromosome maintenance 2 protein.

Ishimi Y, Komamura Y, You Z, Kimura H.

J Biol Chem. 1998 Apr 3;273(14):8369-75.

12.

Reduced Mcm2 expression results in severe stem/progenitor cell deficiency and cancer.

Pruitt SC, Bailey KJ, Freeland A.

Stem Cells. 2007 Dec;25(12):3121-32. Epub 2007 Aug 23.

13.

Effect of an MCM4 mutation that causes tumours in mouse on human MCM4/6/7 complex formation.

Watanabe E, Ohara R, Ishimi Y.

J Biochem. 2012 Aug;152(2):191-8. doi: 10.1093/jb/mvs060. Epub 2012 Jun 4.

PMID:
22668557
14.

A reduction of licensed origins reveals strain-specific replication dynamics in mice.

Kawabata T, Yamaguchi S, Buske T, Luebben SW, Wallace M, Matise I, Schimenti JC, Shima N.

Mamm Genome. 2011 Oct;22(9-10):506-17. doi: 10.1007/s00335-011-9333-7. Epub 2011 May 25.

15.

Getting a grip on licensing: mechanism of stable Mcm2-7 loading onto replication origins.

Cvetic CA, Walter JC.

Mol Cell. 2006 Jan 20;21(2):143-4. Review.

16.

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

Ibarra A, Schwob E, Méndez J.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8956-61. doi: 10.1073/pnas.0803978105. Epub 2008 Jun 25.

17.
18.

Mammalian Mcm2/4/6/7 complex forms a toroidal structure.

Yabuta N, Kajimura N, Mayanagi K, Sato M, Gotow T, Uchiyama Y, Ishimi Y, Nojima H.

Genes Cells. 2003 May;8(5):413-21.

19.

Heterozygous screen in Saccharomyces cerevisiae identifies dosage-sensitive genes that affect chromosome stability.

Strome ED, Wu X, Kimmel M, Plon SE.

Genetics. 2008 Mar;178(3):1193-207. doi: 10.1534/genetics.107.084103. Epub 2008 Feb 1.

20.

Biochemical characterization of fragmented human MCM2.

Komamura-Kohno Y, Tanaka R, Omori A, Kohno T, Ishimi Y.

FEBS J. 2008 Feb;275(4):727-38. doi: 10.1111/j.1742-4658.2007.06239.x. Epub 2008 Jan 11.

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