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Items: 1 to 20 of 83

1.

Genome-wide and fine-resolution association analysis of malaria in West Africa.

Jallow M, Teo YY, Small KS, Rockett KA, Deloukas P, Clark TG, Kivinen K, Bojang KA, Conway DJ, Pinder M, Sirugo G, Sisay-Joof F, Usen S, Auburn S, Bumpstead SJ, Campino S, Coffey A, Dunham A, Fry AE, Green A, Gwilliam R, Hunt SE, Inouye M, Jeffreys AE, Mendy A, Palotie A, Potter S, Ragoussis J, Rogers J, Rowlands K, Somaskantharajah E, Whittaker P, Widden C, Donnelly P, Howie B, Marchini J, Morris A, SanJoaquin M, Achidi EA, Agbenyega T, Allen A, Amodu O, Corran P, Djimde A, Dolo A, Doumbo OK, Drakeley C, Dunstan S, Evans J, Farrar J, Fernando D, Hien TT, Horstmann RD, Ibrahim M, Karunaweera N, Kokwaro G, Koram KA, Lemnge M, Makani J, Marsh K, Michon P, Modiano D, Molyneux ME, Mueller I, Parker M, Peshu N, Plowe CV, Puijalon O, Reeder J, Reyburn H, Riley EM, Sakuntabhai A, Singhasivanon P, Sirima S, Tall A, Taylor TE, Thera M, Troye-Blomberg M, Williams TN, Wilson M, Kwiatkowski DP; Wellcome Trust Case Control Consortium; Malaria Genomic Epidemiology Network.

Nat Genet. 2009 Jun;41(6):657-65. doi: 10.1038/ng.388. Epub 2009 May 24.

2.

Imputation-based meta-analysis of severe malaria in three African populations.

Band G, Le QS, Jostins L, Pirinen M, Kivinen K, Jallow M, Sisay-Joof F, Bojang K, Pinder M, Sirugo G, Conway DJ, Nyirongo V, Kachala D, Molyneux M, Taylor T, Ndila C, Peshu N, Marsh K, Williams TN, Alcock D, Andrews R, Edkins S, Gray E, Hubbart C, Jeffreys A, Rowlands K, Schuldt K, Clark TG, Small KS, Teo YY, Kwiatkowski DP, Rockett KA, Barrett JC, Spencer CC; Malaria Genomic Epidemiology Network.

PLoS Genet. 2013 May;9(5):e1003509. doi: 10.1371/journal.pgen.1003509. Epub 2013 May 23. Erratum in: PLoS Genet. 2013 Jun;9(6). doi:10.1371/annotation/adc2beaf-4bee-4e22-925b-6788d62fe029. Malaria Genomic Epidemiological Network [corrected to Malaria Genomic Epidemiology Network].

3.

Imputation without doing imputation: a new method for the detection of non-genotyped causal variants.

Howey R, Cordell HJ.

Genet Epidemiol. 2014 Apr;38(3):173-90. doi: 10.1002/gepi.21792. Epub 2014 Feb 17.

4.

Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus.

Khor CC, Vannberg FO, Chapman SJ, Walley A, Aucan C, Loke H, White NJ, Peto T, Khor LK, Kwiatkowski D, Day N, Scott A, Berkley JA, Marsh K, Peshu N, Maitland K, Williams TN, Hill AV.

Genes Immun. 2007 Oct;8(7):570-6. Epub 2007 Aug 16.

5.

Methodological challenges of genome-wide association analysis in Africa.

Teo YY, Small KS, Kwiatkowski DP.

Nat Rev Genet. 2010 Feb;11(2):149-60. doi: 10.1038/nrg2731. Review.

6.

Fine mapping of the association with obesity at the FTO locus in African-derived populations.

Hassanein MT, Lyon HN, Nguyen TT, Akylbekova EL, Waters K, Lettre G, Tayo B, Forrester T, Sarpong DF, Stram DO, Butler JL, Wilks R, Liu J, Le Marchand L, Kolonel LN, Zhu X, Henderson B, Cooper R, McKenzie C, Taylor HA Jr, Haiman CA, Hirschhorn JN.

Hum Mol Genet. 2010 Jul 15;19(14):2907-16. doi: 10.1093/hmg/ddq178. Epub 2010 Apr 29.

7.

Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations.

Takeuchi F, Katsuya T, Chakrewarthy S, Yamamoto K, Fujioka A, Serizawa M, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N.

Diabetologia. 2010 Feb;53(2):299-308. doi: 10.1007/s00125-009-1595-1. Epub 2009 Nov 25.

PMID:
19937311
8.

Identifying candidate causal variants via trans-population fine-mapping.

Teo YY, Ong RT, Sim X, Tai ES, Chia KS.

Genet Epidemiol. 2010 Nov;34(7):653-64. doi: 10.1002/gepi.20522.

PMID:
20839287
9.

Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III.

Hanchard N, Diakite M, Koch O, Keating B, Pinder M, Jallow M, Sisay-Joof F, Nijnik A, Wilson J, Udalova I, Kwiatkowski D, Rockett K.

Immunogenetics. 2006 Jun;58(5-6):465-70. Epub 2006 Apr 28.

PMID:
16738941
10.

Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping.

Ong RT, Wang X, Liu X, Teo YY.

Eur J Hum Genet. 2012 Dec;20(12):1300-7. doi: 10.1038/ejhg.2012.88. Epub 2012 May 23.

11.

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Weissglas-Volkov D, Aguilar-Salinas CA, Nikkola E, Deere KA, Cruz-Bautista I, Arellano-Campos O, Muñoz-Hernandez LL, Gomez-Munguia L, Ordoñez-Sánchez ML, Reddy PM, Lusis AJ, Matikainen N, Taskinen MR, Riba L, Cantor RM, Sinsheimer JS, Tusie-Luna T, Pajukanta P.

J Med Genet. 2013 May;50(5):298-308. doi: 10.1136/jmedgenet-2012-101461. Epub 2013 Mar 15.

12.

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, Musani SK, Divers J, Mychaleckyj J, Li M, Papanicolaou GJ, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Ingles SA, Press MF, Chanock SJ, Deming SL, Rodriguez-Gil JL, Palmer CD, Buxbaum S, Ekunwe L, Hirschhorn JN, Henderson BE, Myers S, Haiman CA, Reich D, Patterson N, Wilson JG, Price AL.

PLoS Genet. 2011 Apr;7(4):e1001371. doi: 10.1371/journal.pgen.1001371. Epub 2011 Apr 21.

13.

Genome-wide comparisons of variation in linkage disequilibrium.

Teo YY, Fry AE, Bhattacharya K, Small KS, Kwiatkowski DP, Clark TG.

Genome Res. 2009 Oct;19(10):1849-60. doi: 10.1101/gr.092189.109. Epub 2009 Jun 18.

14.

Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes.

Fry AE, Ghansa A, Small KS, Palma A, Auburn S, Diakite M, Green A, Campino S, Teo YY, Clark TG, Jeffreys AE, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Newton CR, Marsh K, Molyneux ME, Taylor TE, Koram KA, Oduro AR, Rogers WO, Rockett KA, Sabeti PC, Kwiatkowski DP.

Hum Mol Genet. 2009 Jul 15;18(14):2683-92. doi: 10.1093/hmg/ddp192. Epub 2009 Apr 29.

15.

Genome-wide linkage analysis of malaria infection intensity and mild disease.

Timmann C, Evans JA, König IR, Kleensang A, Rüschendorf F, Lenzen J, Sievertsen J, Becker C, Enuameh Y, Kwakye KO, Opoku E, Browne EN, Ziegler A, Nürnberg P, Horstmann RD.

PLoS Genet. 2007 Mar 23;3(3):e48.

16.

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium, Morris AP, Meyer CG, Horstmann RD, Hill AV.

Nat Genet. 2010 Sep;42(9):739-41. doi: 10.1038/ng.639. Epub 2010 Aug 8. Erratum in: Nat Genet. 2011 Oct;43(10):1040.

PMID:
20694014
17.

Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies.

Hao K, Chudin E, McElwee J, Schadt EE.

BMC Genet. 2009 Jun 16;10:27. doi: 10.1186/1471-2156-10-27.

18.

Haplotype variation and genotype imputation in African populations.

Huang L, Jakobsson M, Pemberton TJ, Ibrahim M, Nyambo T, Omar S, Pritchard JK, Tishkoff SA, Rosenberg NA.

Genet Epidemiol. 2011 Dec;35(8):766-80. doi: 10.1002/gepi.20626.

19.

Candidate polymorphisms and severe malaria in a Malian population.

Toure O, Konate S, Sissoko S, Niangaly A, Barry A, Sall AH, Diarra E, Poudiougou B, Sepulveda N, Campino S, Rockett KA, Clark TG, Thera MA, Doumbo O; Collaboration with The MalariaGEN Consortium.

PLoS One. 2012;7(9):e43987. doi: 10.1371/journal.pone.0043987. Epub 2012 Sep 5.

20.

In search of causal variants: refining disease association signals using cross-population contrasts.

Saccone NL, Saccone SF, Goate AM, Grucza RA, Hinrichs AL, Rice JP, Bierut LJ.

BMC Genet. 2008 Aug 29;9:58. doi: 10.1186/1471-2156-9-58.

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