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Results: 1 to 20 of 101

1.

Prospects for clinical cancer metabolomics using stable isotope tracers.

Lane AN, Fan TW, Higashi RM, Tan J, Bousamra M, Miller DM.

Exp Mol Pathol. 2009 Jun;86(3):165-73. doi: 10.1016/j.yexmp.2009.01.005. Epub 2009 Jan 20. Review.

PMID:
19454273
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Stable isotope-assisted metabolomics in cancer research.

Lane AN, Fan TW, Higashi RM.

IUBMB Life. 2008 Feb;60(2):124-9. doi: 10.1002/iub.17. Review.

PMID:
18380001
[PubMed - indexed for MEDLINE]
3.

NMR-based stable isotope resolved metabolomics in systems biochemistry.

Fan TW, Lane AN.

J Biomol NMR. 2011 Apr;49(3-4):267-80. doi: 10.1007/s10858-011-9484-6. Epub 2011 Feb 26. Erratum in: J Biomol NMR. 2011 Apr;49(3-4):325.

PMID:
21350847
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions.

Moseley HN, Lane AN, Belshoff AC, Higashi RM, Fan TW.

BMC Biol. 2011 May 31;9:37. doi: 10.1186/1741-7007-9-37.

PMID:
21627825
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Stable isotope-resolved metabolomics and applications for drug development.

Fan TW, Lorkiewicz PK, Sellers K, Moseley HN, Higashi RM, Lane AN.

Pharmacol Ther. 2012 Mar;133(3):366-91. doi: 10.1016/j.pharmthera.2011.12.007. Epub 2011 Dec 23. Review.

PMID:
22212615
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Stable isotope-resolved metabolomics (SIRM) in cancer research with clinical application to nonsmall cell lung cancer.

Lane AN, Fan TW, Bousamra M 2nd, Higashi RM, Yan J, Miller DM.

OMICS. 2011 Mar;15(3):173-82. doi: 10.1089/omi.2010.0088. Epub 2011 Feb 17. Review.

PMID:
21329461
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

TARDIS-based microbial metabolomics: time and relative differences in systems.

Winder CL, Dunn WB, Goodacre R.

Trends Microbiol. 2011 Jul;19(7):315-22. doi: 10.1016/j.tim.2011.05.004. Epub 2011 Jun 12. Review.

PMID:
21664817
[PubMed - indexed for MEDLINE]
8.

Correcting for the effects of natural abundance in stable isotope resolved metabolomics experiments involving ultra-high resolution mass spectrometry.

Moseley HN.

BMC Bioinformatics. 2010 Mar 17;11:139. doi: 10.1186/1471-2105-11-139.

PMID:
20236542
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation.

Creek DJ, Chokkathukalam A, Jankevics A, Burgess KE, Breitling R, Barrett MP.

Anal Chem. 2012 Oct 16;84(20):8442-7. doi: 10.1021/ac3018795. Epub 2012 Sep 25.

PMID:
22946681
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Isotopomer-based metabolomic analysis by NMR and mass spectrometry.

Lane AN, Fan TW, Higashi RM.

Methods Cell Biol. 2008;84:541-88.

PMID:
17964943
[PubMed - indexed for MEDLINE]
11.

Practical aspects of uniform stable isotope labeling of higher plants for heteronuclear NMR-based metabolomics.

Kikuchi J, Hirayama T.

Methods Mol Biol. 2007;358:273-86.

PMID:
17035691
[PubMed - indexed for MEDLINE]
12.

Stable isotope labeling of Arabidopsis thaliana for an NMR-based metabolomics approach.

Kikuchi J, Shinozaki K, Hirayama T.

Plant Cell Physiol. 2004 Aug;45(8):1099-104.

PMID:
15356336
[PubMed - indexed for MEDLINE]
13.

Stable isotope-assisted metabolomics to detect metabolic flux changes in mammalian cell cultures.

Mueller D, Heinzle E.

Curr Opin Biotechnol. 2013 Feb;24(1):54-9. doi: 10.1016/j.copbio.2012.10.015. Epub 2012 Nov 9. Review.

PMID:
23142545
[PubMed - indexed for MEDLINE]
14.

Nontargeted elucidation of metabolic pathways using stable-isotope tracers and mass spectrometry.

Hiller K, Metallo CM, Kelleher JK, Stephanopoulos G.

Anal Chem. 2010 Aug 1;82(15):6621-8. doi: 10.1021/ac1011574.

PMID:
20608743
[PubMed - indexed for MEDLINE]
15.

Hypoxia-induced metabolic shifts in cancer cells: moving beyond the Warburg effect.

Weljie AM, Jirik FR.

Int J Biochem Cell Biol. 2011 Jul;43(7):981-9. doi: 10.1016/j.biocel.2010.08.009. Epub 2010 Aug 24. Review.

PMID:
20797448
[PubMed - indexed for MEDLINE]
16.

Improved genome annotation through untargeted detection of pathway-specific metabolites.

Bowen BP, Fischer CR, Baran R, Banfield JF, Northen T.

BMC Genomics. 2011 Jun 15;12 Suppl 1:S6. doi: 10.1186/1471-2164-12-S1-S6.

PMID:
21810208
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Systematic NMR analysis of stable isotope labeled metabolite mixtures in plant and animal systems: coarse grained views of metabolic pathways.

Chikayama E, Suto M, Nishihara T, Shinozaki K, Kikuchi J.

PLoS One. 2008;3(11):e3805. doi: 10.1371/journal.pone.0003805. Epub 2008 Nov 25. Erratum in: PLoS One. 2009;4(4). doi: 10.1371/annotation/b9b4135b-d76f-4990-b5e4-a70d85acf8e6. Hirayama, Takashi [removed]. PLoS One. 2009;4(4). doi: 10.1371/annotation/55efe5d9-ca11-4f68-ac03-49a31d803161.

PMID:
19030231
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells.

Metallo CM, Walther JL, Stephanopoulos G.

J Biotechnol. 2009 Nov;144(3):167-74. doi: 10.1016/j.jbiotec.2009.07.010. Epub 2009 Jul 19.

PMID:
19622376
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM).

Fan TW, Lane AN, Higashi RM, Farag MA, Gao H, Bousamra M, Miller DM.

Mol Cancer. 2009 Jun 26;8:41. doi: 10.1186/1476-4598-8-41.

PMID:
19558692
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Metabolomics has great potential for clinical and nutritional care and research with exotic animals.

Dove AD.

Zoo Biol. 2013 May-Jun;32(3):246-50. doi: 10.1002/ZOO.21024. Epub 2012 May 29.

PMID:
22644923
[PubMed - indexed for MEDLINE]

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