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Items: 1 to 20 of 111


What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor?

Michelle C, Vourc'h P, Mignon L, Andres CR.

J Mol Evol. 2009 Jun;68(6):616-28. doi: 10.1007/s00239-009-9225-6. Epub 2009 May 19.


Architecture of the catalytic HPN motif is conserved in all E2 conjugating enzymes.

Cook BW, Shaw GS.

Biochem J. 2012 Jul 15;445(2):167-74. doi: 10.1042/BJ20120504.


Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes.

Pandey R, Müller A, Napoli CA, Selinger DA, Pikaard CS, Richards EJ, Bender J, Mount DW, Jorgensen RA.

Nucleic Acids Res. 2002 Dec 1;30(23):5036-55.


Determinants of functionality in the ubiquitin conjugating enzyme family.

Winn PJ, Religa TL, Battey JN, Banerjee A, Wade RC.

Structure. 2004 Sep;12(9):1563-74.


C-Terminal acidic domain of ubiquitin-conjugating enzymes: a multi-functional conserved intrinsically disordered domain in family 3 of E2 enzymes.

Arrigoni A, Grillo B, Vitriolo A, De Gioia L, Papaleo E.

J Struct Biol. 2012 Jun;178(3):245-59. doi: 10.1016/j.jsb.2012.04.003. Epub 2012 Apr 13.


The family of ubiquitin-conjugating enzymes (E2s): deciding between life and death of proteins.

van Wijk SJ, Timmers HT.

FASEB J. 2010 Apr;24(4):981-93. doi: 10.1096/fj.09-136259. Epub 2009 Nov 25. Review.


Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation.

Burroughs AM, Jaffee M, Iyer LM, Aravind L.

J Struct Biol. 2008 May;162(2):205-18. doi: 10.1016/j.jsb.2007.12.006. Epub 2008 Jan 1.


Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34.

Sadowski M, Suryadinata R, Lai X, Heierhorst J, Sarcevic B.

Mol Cell Biol. 2010 May;30(10):2316-29. doi: 10.1128/MCB.01094-09. Epub 2010 Mar 1.


Crystal structure of a class I ubiquitin conjugating enzyme (Ubc7) from Saccharomyces cerevisiae at 2.9 angstroms resolution.

Cook WJ, Martin PD, Edwards BF, Yamazaki RK, Chau V.

Biochemistry. 1997 Feb 18;36(7):1621-7.


Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.

Page RC, Pruneda JN, Amick J, Klevit RE, Misra S.

Biochemistry. 2012 May 22;51(20):4175-87. doi: 10.1021/bi300058m. Epub 2012 May 14.


Loop 7 of E2 enzymes: an ancestral conserved functional motif involved in the E2-mediated steps of the ubiquitination cascade.

Papaleo E, Casiraghi N, Arrigoni A, Vanoni M, Coccetti P, De Gioia L.

PLoS One. 2012;7(7):e40786. doi: 10.1371/journal.pone.0040786. Epub 2012 Jul 18.


Computational identification of novel chitinase-like proteins in the Drosophila melanogaster genome.

Zhu Q, Deng Y, Vanka P, Brown SJ, Muthukrishnan S, Kramer KJ.

Bioinformatics. 2004 Jan 22;20(2):161-9.


Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.

Olsen SK, Lima CD.

Mol Cell. 2013 Mar 7;49(5):884-96. doi: 10.1016/j.molcel.2013.01.013. Epub 2013 Feb 14.


The ubc-2 gene of Caenorhabditis elegans encodes a ubiquitin-conjugating enzyme involved in selective protein degradation.

Zhen M, Heinlein R, Jones D, Jentsch S, Candido EP.

Mol Cell Biol. 1993 Mar;13(3):1371-7.


Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7).

Arai R, Yoshikawa S, Murayama K, Imai Y, Takahashi R, Shirouzu M, Yokoyama S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Apr 1;62(Pt 4):330-4. Epub 2006 Mar 25.


Origin and evolution of ubiquitin-conjugating enzymes from Guillardia theta nucleomorph to hominoid.

Ying M, Zhan Z, Wang W, Chen D.

Gene. 2009 Nov 15;447(2):72-85. doi: 10.1016/j.gene.2009.07.021. Epub 2009 Aug 5.


The role of lineage-specific gene family expansion in the evolution of eukaryotes.

Lespinet O, Wolf YI, Koonin EV, Aravind L.

Genome Res. 2002 Jul;12(7):1048-59.


An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes.

Papaleo E, Ranzani V, Tripodi F, Vitriolo A, Cirulli C, Fantucci P, Alberghina L, Vanoni M, De Gioia L, Coccetti P.

PLoS Comput Biol. 2011 May;7(5):e1002056. doi: 10.1371/journal.pcbi.1002056. Epub 2011 May 26.

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