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Results: 1 to 20 of 96

1.

Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas.

Le LQ, Shipman T, Burns DK, Parada LF.

Cell Stem Cell. 2009 May 8;4(5):453-63. doi: 10.1016/j.stem.2009.03.017.

PMID:
19427294
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The neurofibroma cell of origin: SKPs expand the playing field.

Morris ZS, McClatchey AI.

Cell Stem Cell. 2009 May 8;4(5):371-2. doi: 10.1016/j.stem.2009.04.010.

PMID:
19427284
[PubMed - indexed for MEDLINE]
Free Article
3.

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.

Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, Robertson K, Hutchins G, Parada LF, Clapp DW.

Cell. 2008 Oct 31;135(3):437-48. doi: 10.1016/j.cell.2008.08.041.

PMID:
18984156
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Tumor microenvironment and neurofibromatosis type I: connecting the GAPs.

Le LQ, Parada LF.

Oncogene. 2007 Jul 12;26(32):4609-16. Epub 2007 Feb 12. Review.

PMID:
17297459
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration-implications for increased neurofibroma formation during pregnancy.

Nebesio TD, Ming W, Chen S, Clegg T, Yuan J, Yang Y, Estwick SA, Li Y, Li X, Hingtgen CM, Yang FC.

Glia. 2007 Apr 1;55(5):527-36.

PMID:
17236191
[PubMed - indexed for MEDLINE]
6.

Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells.

Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW.

J Clin Invest. 2003 Dec;112(12):1851-61.

PMID:
14679180
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1.

Arima Y, Hayashi H, Kamata K, Goto TM, Sasaki M, Kuramochi A, Saya H.

Exp Dermatol. 2010 Aug;19(8):e136-41. doi: 10.1111/j.1600-0625.2009.01017.x.

PMID:
20002172
[PubMed - indexed for MEDLINE]
Free Article
8.

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.

Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N.

Cancer Cell. 2008 Feb;13(2):105-16. doi: 10.1016/j.ccr.2007.12.027.

PMID:
18242511
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells.

Munchhof AM, Li F, White HA, Mead LE, Krier TR, Fenoglio A, Li X, Yuan J, Yang FC, Ingram DA.

Hum Mol Genet. 2006 Jun 1;15(11):1858-69. Epub 2006 Apr 28.

PMID:
16648142
[PubMed - indexed for MEDLINE]
Free Article
10.

The activation of the WNT signaling pathway is a Hallmark in neurofibromatosis type 1 tumorigenesis.

Luscan A, Shackleford G, Masliah-Planchon J, Laurendeau I, Ortonne N, Varin J, Lallemand F, Leroy K, Dumaine V, Hivelin M, Borderie D, De Raedt T, Valeyrie-Allanore L, Larousserie F, Terris B, Lantieri L, Vidaud M, Vidaud D, Wolkenstein P, Parfait B, Bièche I, Massaad C, Pasmant E.

Clin Cancer Res. 2014 Jan 15;20(2):358-71. doi: 10.1158/1078-0432.CCR-13-0780. Epub 2013 Nov 11.

PMID:
24218515
[PubMed - indexed for MEDLINE]
11.

Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential.

Williams JP, Wu J, Johansson G, Rizvi TA, Miller SC, Geiger H, Malik P, Li W, Mukouyama YS, Cancelas JA, Ratner N.

Cell Stem Cell. 2008 Dec 4;3(6):658-69. doi: 10.1016/j.stem.2008.10.003.

PMID:
19041782
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas.

Tucker T, Riccardi VM, Brown C, Fee J, Sutcliffe M, Vielkind J, Wechsler J, Wolkenstein P, Friedman JM.

J Neurosci Res. 2011 Sep;89(9):1451-60. doi: 10.1002/jnr.22654. Epub 2011 Jun 14.

PMID:
21674567
[PubMed - indexed for MEDLINE]
13.

Influence of hormones and hormone metabolites on the growth of Schwann cells derived from embryonic stem cells and on tumor cell lines expressing variable levels of neurofibromin.

Roth TM, Ramamurthy P, Muir D, Wallace MR, Zhu Y, Chang L, Barald KF.

Dev Dyn. 2008 Feb;237(2):513-24. doi: 10.1002/dvdy.21430.

PMID:
18213578
[PubMed - indexed for MEDLINE]
Free Article
14.

The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.

Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A.

Oncogene. 2001 Jan 4;20(1):97-105.

PMID:
11244508
[PubMed - indexed for MEDLINE]
Free Article
15.

Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.

Brossier NM, Carroll SL.

Brain Res Bull. 2012 May 1;88(1):58-71. doi: 10.1016/j.brainresbull.2011.08.005. Epub 2011 Aug 10. Review.

PMID:
21855613
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve.

Ribeiro S, Napoli I, White IJ, Parrinello S, Flanagan AM, Suter U, Parada LF, Lloyd AC.

Cell Rep. 2013 Oct 17;5(1):126-36. doi: 10.1016/j.celrep.2013.08.033. Epub 2013 Sep 26.

PMID:
24075988
[PubMed - indexed for MEDLINE]
Free Article
17.

Molecular, genetic, and cellular pathogenesis of neurofibromas and surgical implications.

Gottfried ON, Viskochil DH, Fults DW, Couldwell WT.

Neurosurgery. 2006 Jan;58(1):1-16; discussion 1-16. Review.

PMID:
16385324
[PubMed - indexed for MEDLINE]
18.

It takes two to tango: mast cell and Schwann cell interactions in neurofibromas.

Viskochil DH.

J Clin Invest. 2003 Dec;112(12):1791-3. Review.

PMID:
14679174
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Skin-derived precursor cells as an in vitro modelling tool for the study of type 1 neurofibromatosis.

Gutiérrez-Rivera A, Iribar H, Tuneu A, Izeta A.

Stem Cells Int. 2012;2012:646725. doi: 10.1155/2012/646725. Epub 2012 Apr 1.

PMID:
22550514
[PubMed]
Free PMC Article
20.

Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications.

Gottfried ON, Viskochil DH, Couldwell WT.

Neurosurg Focus. 2010 Jan;28(1):E8. doi: 10.3171/2009.11.FOCUS09221.

PMID:
20043723
[PubMed - indexed for MEDLINE]

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