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Results: 1 to 20 of 165

1.

Structure-activity relationships and human relevance for perfluoroalkyl acid-induced transcriptional activation of peroxisome proliferation in liver cell cultures.

Bjork JA, Wallace KB.

Toxicol Sci. 2009 Sep;111(1):89-99. doi: 10.1093/toxsci/kfp093. Epub 2009 Apr 30.

PMID:
19407336
[PubMed - indexed for MEDLINE]
Free Article
2.

Mechanisms of peroxisome proliferation by perfluorooctanoic acid and endogenous fatty acids.

Intrasuksri U, Rangwala SM, O'Brien M, Noonan DJ, Feller DR.

Gen Pharmacol. 1998 Aug;31(2):187-97.

PMID:
9688458
[PubMed - indexed for MEDLINE]
3.

Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes.

Ammerschlaeger M, Beigel J, Klein KU, Mueller SO.

Toxicol Sci. 2004 Apr;78(2):229-40. Epub 2004 Feb 19.

PMID:
14976357
[PubMed - indexed for MEDLINE]
Free Article
4.

Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths.

Wolf CJ, Takacs ML, Schmid JE, Lau C, Abbott BD.

Toxicol Sci. 2008 Nov;106(1):162-71. doi: 10.1093/toxsci/kfn166. Epub 2008 Aug 18.

PMID:
18713766
[PubMed - indexed for MEDLINE]
Free Article
5.

Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis.

Yeldandi AV, Rao MS, Reddy JK.

Mutat Res. 2000 Mar 17;448(2):159-77. Review.

PMID:
10725470
[PubMed - indexed for MEDLINE]
6.

Activation of PPARalpha and PPARgamma by environmental phthalate monoesters.

Hurst CH, Waxman DJ.

Toxicol Sci. 2003 Aug;74(2):297-308. Epub 2003 Jun 12.

PMID:
12805656
[PubMed - indexed for MEDLINE]
Free Article
7.

Transactivation potencies of the Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor α by perfluoroalkyl carboxylates and sulfonates: estimation of PFOA induction equivalency factors.

Ishibashi H, Kim EY, Iwata H.

Environ Sci Technol. 2011 Apr 1;45(7):3123-30. doi: 10.1021/es103748s. Epub 2011 Mar 7.

PMID:
21381677
[PubMed - indexed for MEDLINE]
8.

Transcription of genes involved in fat metabolism in chicken embryos exposed to the peroxisome proliferator-activated receptor alpha (PPARα) agonist GW7647 or to perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA).

Strömqvist M, Olsson JA, Kärrman A, Brunström B.

Comp Biochem Physiol C Toxicol Pharmacol. 2012 Jun;156(1):29-36. doi: 10.1016/j.cbpc.2012.03.004. Epub 2012 Mar 21.

PMID:
22465071
[PubMed - indexed for MEDLINE]
9.

Exposure to perfluorooctane sulfonate or fenofibrate causes PPAR-alpha dependent transcriptional responses in chicken embryo hepatocytes.

Cwinn MA, Jones SP, Kennedy SW.

Comp Biochem Physiol C Toxicol Pharmacol. 2008 Aug;148(2):165-71. doi: 10.1016/j.cbpc.2008.05.002. Epub 2008 May 10.

PMID:
18565798
[PubMed - indexed for MEDLINE]
11.
12.

Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in rat primary hepatocyte culture by peroxisome proliferators.

Bell DR, Elcombe CR.

Biochem J. 1991 Nov 15;280 ( Pt 1):249-53.

PMID:
1720616
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Peroxisome proliferators activate growth regulatory pathways largely via peroxisome proliferator-activated receptor alpha-independent mechanisms.

Pauley CJ, Ledwith BJ, Kaplanski C.

Cell Signal. 2002 Apr;14(4):351-8.

PMID:
11858942
[PubMed - indexed for MEDLINE]
14.

Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 2. Molecular characterization, expression level, and transcriptional activation of peroxisome proliferator-activated receptor alpha.

Ishibashi H, Iwata H, Kim EY, Tao L, Kannan K, Tanabe S, Batoev VB, Petrov EA.

Environ Sci Technol. 2008 Apr 1;42(7):2302-8.

PMID:
18504957
[PubMed - indexed for MEDLINE]
15.

Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism.

Kalajdzic T, Faour WH, He QW, Fahmi H, Martel-Pelletier J, Pelletier JP, Di Battista JA.

Arthritis Rheum. 2002 Feb;46(2):494-506.

PMID:
11840453
[PubMed - indexed for MEDLINE]
16.

Profiling of gene expression in rat liver and rat primary cultured hepatocytes treated with peroxisome proliferators.

Tamura K, Ono A, Miyagishima T, Nagao T, Urushidani T.

J Toxicol Sci. 2006 Dec;31(5):471-90.

PMID:
17202761
[PubMed - indexed for MEDLINE]
Free Article
17.

Underlying mechanisms of pharmacology and toxicity of a novel PPAR agonist revealed using rodent and canine hepatocytes.

Guo Y, Jolly RA, Halstead BW, Baker TK, Stutz JP, Huffman M, Calley JN, West A, Gao H, Searfoss GH, Li S, Irizarry AR, Qian HR, Stevens JL, Ryan TP.

Toxicol Sci. 2007 Apr;96(2):294-309. Epub 2007 Jan 25.

PMID:
17255113
[PubMed - indexed for MEDLINE]
Free Article
18.

trans-activation of PPARalpha and induction of PPARalpha target genes by perfluorooctane-based chemicals.

Shipley JM, Hurst CH, Tanaka SS, DeRoos FL, Butenhoff JL, Seacat AM, Waxman DJ.

Toxicol Sci. 2004 Jul;80(1):151-60. Epub 2004 Apr 7.

PMID:
15071170
[PubMed - indexed for MEDLINE]
Free Article
19.

Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene.

Varanasi U, Chu R, Huang Q, Castellon R, Yeldandi AV, Reddy JK.

J Biol Chem. 1996 Jan 26;271(4):2147-55. Erratum in: J Biol Chem 1998 Nov 13;273(46):30842.

PMID:
8567672
[PubMed - indexed for MEDLINE]
Free Article
20.

Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha.

Ng VY, Huang Y, Reddy LM, Falck JR, Lin ET, Kroetz DL.

Drug Metab Dispos. 2007 Jul;35(7):1126-34. Epub 2007 Apr 12.

PMID:
17431031
[PubMed - indexed for MEDLINE]
Free Article
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