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Items: 1 to 20 of 243

1.

Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei.

Signorell A, Gluenz E, Rettig J, Schneider A, Shaw MK, Gull K, Bütikofer P.

Mol Microbiol. 2009 May;72(4):1068-79. doi: 10.1111/j.1365-2958.2009.06713.x. Epub 2009 Apr 28.

2.

The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei.

Gibellini F, Hunter WN, Smith TK.

Mol Microbiol. 2009 Sep;73(5):826-43. doi: 10.1111/j.1365-2958.2009.06764.x. Epub 2009 Jun 23.

3.

Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway.

Signorell A, Rauch M, Jelk J, Ferguson MA, Bütikofer P.

J Biol Chem. 2008 Aug 29;283(35):23636-44. doi: 10.1074/jbc.M803600200. Epub 2008 Jun 28.

4.

Cell morphogenesis of Trypanosoma brucei requires the paralogous, differentially expressed calpain-related proteins CAP5.5 and CAP5.5V.

Olego-Fernandez S, Vaughan S, Shaw MK, Gull K, Ginger ML.

Protist. 2009 Nov;160(4):576-90. doi: 10.1016/j.protis.2009.05.003. Epub 2009 Aug 4.

PMID:
19656721
5.
6.

Phosphatidylglycerophosphate synthase associates with a mitochondrial inner membrane complex and is essential for growth of Trypanosoma brucei.

Serricchio M, Bütikofer P.

Mol Microbiol. 2013 Feb;87(3):569-79. doi: 10.1111/mmi.12116. Epub 2012 Dec 11.

7.

Trypanosoma brucei vacuolar protein sorting 41 (VPS41) is required for intracellular iron utilization and maintenance of normal cellular morphology.

Lu S, Suzuki T, Iizuka N, Ohshima S, Yabu Y, Suzuki M, Wen L, Ohta N.

Parasitology. 2007 Oct;134(Pt 11):1639-47. Epub 2007 Jun 19.

PMID:
17577424
8.

Gene knockdown of gamma-glutamylcysteine synthetase by RNAi in the parasitic protozoa Trypanosoma brucei demonstrates that it is an essential enzyme.

Huynh TT, Huynh VT, Harmon MA, Phillips MA.

J Biol Chem. 2003 Oct 10;278(41):39794-800. Epub 2003 Jul 29.

9.

The small ubiquitin-like modifier (SUMO) is essential in cell cycle regulation in Trypanosoma brucei.

Liao S, Wang T, Fan K, Tu X.

Exp Cell Res. 2010 Mar 10;316(5):704-15. doi: 10.1016/j.yexcr.2009.12.017. Epub 2010 Jan 4.

PMID:
20045687
10.

Knock-downs of iron-sulfur cluster assembly proteins IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei.

Smíd O, Horáková E, Vilímová V, Hrdy I, Cammack R, Horváth A, Lukes J, Tachezy J.

J Biol Chem. 2006 Sep 29;281(39):28679-86. Epub 2006 Aug 1.

11.

Phosphatidylethanolamine is the precursor of the ethanolamine phosphoglycerol moiety bound to eukaryotic elongation factor 1A.

Signorell A, Jelk J, Rauch M, Bütikofer P.

J Biol Chem. 2008 Jul 18;283(29):20320-9. doi: 10.1074/jbc.M802430200. Epub 2008 May 22.

12.

Sphingolipid synthesis is necessary for kinetoplast segregation and cytokinesis in Trypanosoma brucei.

Fridberg A, Olson CL, Nakayasu ES, Tyler KM, Almeida IC, Engman DM.

J Cell Sci. 2008 Feb 15;121(Pt 4):522-35. doi: 10.1242/jcs.016741. Epub 2008 Jan 29.

14.

Downregulation of the nuclear-encoded subunits of the complexes III and IV disrupts their respective complexes but not complex I in procyclic Trypanosoma brucei.

Horváth A, Horáková E, Dunajcíková P, Verner Z, Pravdová E, Slapetová I, Cuninková L, Lukes J.

Mol Microbiol. 2005 Oct;58(1):116-30.

15.

Mitochondrial fatty acid synthesis in Trypanosoma brucei.

Stephens JL, Lee SH, Paul KS, Englund PT.

J Biol Chem. 2007 Feb 16;282(7):4427-36. Epub 2006 Dec 12.

17.
18.

CRK9 contributes to regulation of mitosis and cytokinesis in the procyclic form of Trypanosoma brucei.

Gourguechon S, Wang CC.

BMC Cell Biol. 2009 Sep 21;10:68. doi: 10.1186/1471-2121-10-68.

19.

Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis.

Serricchio M, Bütikofer P.

FEBS J. 2011 Apr;278(7):1035-46. doi: 10.1111/j.1742-4658.2011.08012.x. Epub 2011 Feb 3. Review.

20.

Mitochondrial substrate level phosphorylation is essential for growth of procyclic Trypanosoma brucei.

Bochud-Allemann N, Schneider A.

J Biol Chem. 2002 Sep 6;277(36):32849-54. Epub 2002 Jul 2.

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