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Results: 1 to 20 of 203

1.

Successful liver transplantation for Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria treated with the anti-complement antibody eculizumab.

Singer AL, Locke JE, Stewart ZA, Lonze BE, Hamilton JP, Scudiere JR, Anders RA, Rother RP, Brodsky RA, Cameron AM.

Liver Transpl. 2009 May;15(5):540-3. doi: 10.1002/lt.21714.

PMID:
19399743
[PubMed - indexed for MEDLINE]
Free Article
2.

Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: the AEGIS clinical trial.

Kanakura Y, Ohyashiki K, Shichishima T, Okamoto S, Ando K, Ninomiya H, Kawaguchi T, Nakao S, Nakakuma H, Nishimura J, Kinoshita T, Bedrosian CL, Valentine ME, Khursigara G, Ozawa K, Omine M.

Int J Hematol. 2011 Jan;93(1):36-46. doi: 10.1007/s12185-010-0748-9. Epub 2011 Jan 12.

PMID:
21222185
[PubMed - indexed for MEDLINE]
3.

Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation.

Brodsky A, Mazzocchi O, Sánchez F, Khursigara G, Malhotra S, Volpacchio M.

Exp Hematol Oncol. 2012 Sep 6;1(1):26. doi: 10.1186/2162-3619-1-26.

PMID:
23210433
[PubMed]
Free PMC Article
4.

Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria.

Rother RP, Rollins SA, Mojcik CF, Brodsky RA, Bell L.

Nat Biotechnol. 2007 Nov;25(11):1256-64. Erratum in: Nat Biotechnol. 2007 Dec;25(12):1488.

PMID:
17989688
[PubMed - indexed for MEDLINE]
5.

Liver transplantation for PNH with Budd-Chiari syndrome. A case report.

Schattenfroh N, Bechstein WO, Blumhardt G, Langer R, Lobeck H, Langrehr JM, Neuhaus P.

Transpl Int. 1993;6(6):354-8.

PMID:
8297467
[PubMed - indexed for MEDLINE]
6.

Erythopoietin treatment during complement inhibition with eculizumab in a patient with paroxysmal nocturnal hemoglobinuria.

Hill A, Richards SJ, Rother RP, Hillmen P.

Haematologica. 2007 Mar;92(3):e31-3.

PMID:
17405753
[PubMed - indexed for MEDLINE]
Free Article
7.

[Paroxysmal nocturnal hemoglobinuria].

Peffault de Latour R, Amoura Z, Socié G.

Rev Med Interne. 2010 Mar;31(3):200-7. doi: 10.1016/j.revmed.2008.12.020. Epub 2009 Mar 19. Review. French.

PMID:
19303177
[PubMed - indexed for MEDLINE]
8.

Paroxysmal nocturnal hemoglobinuria and the complement system: recent insights and novel anticomplement strategies.

Risitano AM.

Adv Exp Med Biol. 2013;735:155-72. Review.

PMID:
23402025
[PubMed - indexed for MEDLINE]
9.

Paroxysmal nocturnal hemoglobinuria in Budd-Chiari syndrome: findings from a cohort study.

Hoekstra J, Leebeek FW, Plessier A, Raffa S, Darwish Murad S, Heller J, Hadengue A, Chagneau C, Elias E, Primignani M, Garcia-Pagan JC, Valla DC, Janssen HL; European Network for Vascular Disorders of the Liver.

J Hepatol. 2009 Oct;51(4):696-706. doi: 10.1016/j.jhep.2009.06.019. Epub 2009 Jul 23.

PMID:
19664836
[PubMed - indexed for MEDLINE]
10.

Recurrence of Budd-Chiari syndrome after liver transplantation in paroxysmal nocturnal hemoglobinuria.

Bahr MJ, Schubert J, Bleck JS, Tietge UJ, Boozari B, Schmidt RE, Klempnauer J, Strassburg CP, Manns MP.

Transpl Int. 2003 Dec;16(12):890-4. Epub 2003 Jul 24.

PMID:
14652717
[PubMed - indexed for MEDLINE]
11.

Long-term effect of the complement inhibitor eculizumab on kidney function in patients with paroxysmal nocturnal hemoglobinuria.

Hillmen P, Elebute M, Kelly R, Urbano-Ispizua A, Hill A, Rother RP, Khursigara G, Fu CL, Omine M, Browne P, Rosse W.

Am J Hematol. 2010 Aug;85(8):553-9. doi: 10.1002/ajh.21757. Erratum in: Am J Hematol. 2010 Nov;85(11):911.

PMID:
20658586
[PubMed - indexed for MEDLINE]
12.

Liver transplant for Budd-Chiari syndrome caused by paroxysmal nocturnal hemoglobinuria.

Yedibela S, Hohenberger W.

Exp Clin Transplant. 2008 Sep;6(3):180-3.

PMID:
18954293
[PubMed - indexed for MEDLINE]
Free Article
13.

Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization.

Hill A, Rother RP, Arnold L, Kelly R, Cullen MJ, Richards SJ, Hillmen P.

Haematologica. 2010 Apr;95(4):567-73. doi: 10.3324/haematol.2009.007229. Epub 2010 Feb 9.

PMID:
20145265
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

[Eculizumab in paroxysmal nocturnal hemoglobinuria].

Socié G, Varoqueaux N, Peffault de Latour R.

Med Sci (Paris). 2009 Dec;25(12):1126-9. doi: 10.1051/medsci/200925121126. Review. French.

PMID:
20035691
[PubMed - indexed for MEDLINE]
Free Article
15.

Catheter-directed thrombolysis and thrombectomy for the Budd-Chiari syndrome in paroxysmal nocturnal hemoglobinuria in three patients.

Kuo GP, Brodsky RA, Kim HS.

J Vasc Interv Radiol. 2006 Feb;17(2 Pt 1):383-7.

PMID:
16517788
[PubMed - indexed for MEDLINE]
16.

Mechanisms and clinical implications of thrombosis in paroxysmal nocturnal hemoglobinuria.

Van Bijnen ST, Van Heerde WL, Muus P.

J Thromb Haemost. 2012 Jan;10(1):1-10. doi: 10.1111/j.1538-7836.2011.04562.x. Review.

PMID:
22077430
[PubMed - indexed for MEDLINE]
17.

Eculizumab: A novel therapy for paroxysmal nocturnal hemoglobinuria.

Zareba KM.

Drugs Today (Barc). 2007 Aug;43(8):539-46. Review.

PMID:
17925885
[PubMed - indexed for MEDLINE]
18.

How I treat paroxysmal nocturnal hemoglobinuria.

Brodsky RA.

Blood. 2009 Jun 25;113(26):6522-7. doi: 10.1182/blood-2009-03-195966. Epub 2009 Apr 16.

PMID:
19372253
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A novel approach to preventing the hemolysis of paroxysmal nocturnal hemoglobinuria: both complement-mediated cytolysis and C3 deposition are blocked by a monoclonal antibody specific for the alternative pathway of complement.

Lindorfer MA, Pawluczkowycz AW, Peek EM, Hickman K, Taylor RP, Parker CJ.

Blood. 2010 Mar 18;115(11):2283-91. doi: 10.1182/blood-2009-09-244285. Epub 2010 Jan 12.

PMID:
20068220
[PubMed - indexed for MEDLINE]
Free Article
20.

Eculizumab: a guide to its use in paroxysmal nocturnal hemoglobinuria.

Keating GM, Lyseng-Williamson KA, McKeage K.

BioDrugs. 2012 Apr 1;26(2):125-30. doi: 10.2165/11208420-000000000-00000.

PMID:
22350448
[PubMed - indexed for MEDLINE]

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