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Results: 1 to 20 of 813

1.

Aptamers against prion proteins and prions.

Gilch S, Schätzl HM.

Cell Mol Life Sci. 2009 Aug;66(15):2445-55. doi: 10.1007/s00018-009-0031-5. Epub 2009 Apr 25. Review.

PMID:
19396399
[PubMed - indexed for MEDLINE]
2.

Peptide aptamers expressed in the secretory pathway interfere with cellular PrPSc formation.

Gilch S, Kehler C, Schätzl HM.

J Mol Biol. 2007 Aug 10;371(2):362-73. Epub 2007 May 25.

PMID:
17574575
[PubMed - indexed for MEDLINE]
3.

Utility of RNAi-mediated prnp gene silencing in neuroblastoma cells permanently infected by prions: potentials and limitations.

Kim Y, Han B, Titlow W, Mays CE, Kwon M, Ryou C.

Antiviral Res. 2009 Nov;84(2):185-93. doi: 10.1016/j.antiviral.2009.09.002. Epub 2009 Sep 11.

PMID:
19748523
[PubMed - indexed for MEDLINE]
4.

Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation.

Gilch S, Nunziante M, Ertmer A, Schätzl HM.

Vet Microbiol. 2007 Aug 31;123(4):377-86. Epub 2007 Apr 8. Review.

PMID:
17493775
[PubMed - indexed for MEDLINE]
5.

On safari with PrP: prion diseases of animals.

Westaway D, Carlson GA, Prusiner SB.

Trends Microbiol. 1995 Apr;3(4):141-7. Review.

PMID:
7613755
[PubMed - indexed for MEDLINE]
6.

DNA aptamers that bind to PrP(C) and not PrP(Sc) show sequence and structure specificity.

Takemura K, Wang P, Vorberg I, Surewicz W, Priola SA, Kanthasamy A, Pottathil R, Chen SG, Sreevatsan S.

Exp Biol Med (Maywood). 2006 Feb;231(2):204-14. Erratum in: Exp Biol Med (Maywood). 2006 Apr;231(4):485.

PMID:
16446497
[PubMed - indexed for MEDLINE]
7.

Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality.

Coleman BM, Harrison CF, Guo B, Masters CL, Barnham KJ, Lawson VA, Hill AF.

J Virol. 2014 Mar;88(5):2690-703. doi: 10.1128/JVI.02720-13. Epub 2013 Dec 18.

PMID:
24352465
[PubMed - indexed for MEDLINE]
8.

New insights into prion structure and toxicity.

Harris DA, True HL.

Neuron. 2006 May 4;50(3):353-7. Review.

PMID:
16675391
[PubMed - indexed for MEDLINE]
Free Article
9.

DNA converts cellular prion protein into the beta-sheet conformation and inhibits prion peptide aggregation.

Cordeiro Y, Machado F, Juliano L, Juliano MA, Brentani RR, Foguel D, Silva JL.

J Biol Chem. 2001 Dec 28;276(52):49400-9. Epub 2001 Oct 16.

PMID:
11604397
[PubMed - indexed for MEDLINE]
Free Article
10.

Targeting prion proteins in neurodegenerative disease.

Gilch S, Krammer C, Schätzl HM.

Expert Opin Biol Ther. 2008 Jul;8(7):923-40. doi: 10.1517/14712598.8.7.923 . Review.

PMID:
18549323
[PubMed - indexed for MEDLINE]
11.

Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins.

Bibby DF, Gill AC, Kirby L, Farquhar CF, Bruce ME, Garson JA.

J Virol Methods. 2008 Jul;151(1):107-15. doi: 10.1016/j.jviromet.2008.03.013. Epub 2008 Apr 23.

PMID:
18433888
[PubMed - indexed for MEDLINE]
12.

Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds.

Phuan PW, Zorn JA, Safar J, Giles K, Prusiner SB, Cohen FE, May BC.

J Gen Virol. 2007 Apr;88(Pt 4):1392-401.

PMID:
17374787
[PubMed - indexed for MEDLINE]
Free Article
13.

Therapy in prion diseases: from molecular and cellular biology to therapeutic targets.

Krammer C, Vorberg I, Schätzl HM, Gilch S.

Infect Disord Drug Targets. 2009 Feb;9(1):3-14.

PMID:
19200010
[PubMed - indexed for MEDLINE]
14.

Evolving views in prion glycosylation: functional and pathological implications.

Ermonval M, Mouillet-Richard S, Codogno P, Kellermann O, Botti J.

Biochimie. 2003 Jan-Feb;85(1-2):33-45. Review.

PMID:
12765773
[PubMed - indexed for MEDLINE]
15.
16.

A transmembrane form of the prion protein in neurodegenerative disease.

Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR.

Science. 1998 Feb 6;279(5352):827-34.

PMID:
9452375
[PubMed - indexed for MEDLINE]
Free Article
17.

The role of rafts in the fibrillization and aggregation of prions.

Pinheiro TJ.

Chem Phys Lipids. 2006 Jun;141(1-2):66-71. Epub 2006 Mar 27. Review.

PMID:
16647049
[PubMed - indexed for MEDLINE]
18.

Prion protein self-interactions: a gateway to novel therapeutic strategies?

Rigter A, Langeveld JP, van Zijderveld FG, Bossers A.

Vaccine. 2010 Nov 16;28(49):7810-23. doi: 10.1016/j.vaccine.2010.09.012. Epub 2010 Oct 20. Review.

PMID:
20932496
[PubMed - indexed for MEDLINE]
19.

Prion protein functions and dysfunction in prion diseases.

Sakudo A, Ikuta K.

Curr Med Chem. 2009;16(3):380-9. Review.

PMID:
19149584
[PubMed - indexed for MEDLINE]
20.

Aggregation and fibrillization of prions in lipid membranes.

Kazlauskaite J, Pinheiro TJ.

Biochem Soc Symp. 2005;(72):211-22. Review.

PMID:
15649144
[PubMed - indexed for MEDLINE]

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