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Results: 1 to 20 of 222

1.

siRNA vs. shRNA: similarities and differences.

Rao DD, Vorhies JS, Senzer N, Nemunaitis J.

Adv Drug Deliv Rev. 2009 Jul 25;61(9):746-59. doi: 10.1016/j.addr.2009.04.004. Epub 2009 Apr 20. Review.

PMID:
19389436
[PubMed - indexed for MEDLINE]
2.

In vivo application of RNA interference: from functional genomics to therapeutics.

Lu PY, Xie F, Woodle MC.

Adv Genet. 2005;54:117-42. Review.

PMID:
16096010
[PubMed - indexed for MEDLINE]
3.

Nonviral vector-mediated RNA interference: its gene silencing characteristics and important factors to achieve RNAi-based gene therapy.

Takahashi Y, Nishikawa M, Takakura Y.

Adv Drug Deliv Rev. 2009 Jul 25;61(9):760-6. doi: 10.1016/j.addr.2009.04.006. Epub 2009 Apr 20. Review.

PMID:
19386274
[PubMed - indexed for MEDLINE]
4.

Comparative assessment of siRNA and shRNA off target effects: what is slowing clinical development.

Rao DD, Senzer N, Cleary MA, Nemunaitis J.

Cancer Gene Ther. 2009 Nov;16(11):807-9. doi: 10.1038/cgt.2009.53. Epub 2009 Aug 28. Review.

PMID:
19713999
[PubMed - indexed for MEDLINE]
5.

RNA interference: from gene silencing to gene-specific therapeutics.

Leung RK, Whittaker PA.

Pharmacol Ther. 2005 Aug;107(2):222-39. Review.

PMID:
15908010
[PubMed - indexed for MEDLINE]
6.

Therapeutic potential of RNA interference against cancer.

Takeshita F, Ochiya T.

Cancer Sci. 2006 Aug;97(8):689-96. Review.

PMID:
16863503
[PubMed - indexed for MEDLINE]
7.

Small RNAs and non-small cell lung cancer.

Tong AW.

Curr Mol Med. 2006 May;6(3):339-49. Review.

PMID:
16712479
[PubMed - indexed for MEDLINE]
8.

shRNA expression constructs designed directly from siRNA oligonucleotide sequences.

Barøy T, Sørensen K, Lindeberg MM, Frengen E.

Mol Biotechnol. 2010 Jun;45(2):116-20. doi: 10.1007/s12033-010-9247-8.

PMID:
20119685
[PubMed - indexed for MEDLINE]
9.

Transkingdom RNA interference (tkRNAi) as a new delivery tool for therapeutic RNA.

Aigner A.

Expert Opin Biol Ther. 2009 Dec;9(12):1533-42. doi: 10.1517/14712590903307354. Review.

PMID:
19769540
[PubMed - indexed for MEDLINE]
10.

A quick and efficient approach for gene silencing by using triple putative microRNA-based short hairpin RNAs.

Shan ZX, Lin QX, Yang M, Deng CY, Kuang SJ, Zhou ZL, Xiao DZ, Liu XY, Lin SG, Yu XY.

Mol Cell Biochem. 2009 Mar;323(1-2):81-9. doi: 10.1007/s11010-008-9966-3. Epub 2008 Nov 27.

PMID:
19037714
[PubMed - indexed for MEDLINE]
11.

Nonviral delivery vehicles for use in short hairpin RNA-based cancer therapies.

Vorhies JS, Nemunaitis J.

Expert Rev Anticancer Ther. 2007 Mar;7(3):373-82. Review.

PMID:
17338656
[PubMed - indexed for MEDLINE]
12.

Strategies for short hairpin RNA delivery in cancer gene therapy.

Wang SL, Yao HH, Qin ZH.

Expert Opin Biol Ther. 2009 Nov;9(11):1357-68. doi: 10.1517/14712590903236843. Review.

PMID:
19761417
[PubMed - indexed for MEDLINE]
13.

Potency of siRNA versus shRNA mediated knockdown in vivo.

McAnuff MA, Rettig GR, Rice KG.

J Pharm Sci. 2007 Nov;96(11):2922-30.

PMID:
17518360
[PubMed - indexed for MEDLINE]
14.

Enzymatically prepared RNAi libraries.

Buchholz F, Kittler R, Slabicki M, Theis M.

Nat Methods. 2006 Sep;3(9):696-700. Review.

PMID:
16929314
[PubMed - indexed for MEDLINE]
15.

Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity.

Akhtar S, Benter I.

Adv Drug Deliv Rev. 2007 Mar 30;59(2-3):164-82. Epub 2007 Mar 21. Review.

PMID:
17481774
[PubMed - indexed for MEDLINE]
16.

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.

Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, Davis CR, Marion P, Salazar F, Kay MA.

Nature. 2006 May 25;441(7092):537-41.

PMID:
16724069
[PubMed - indexed for MEDLINE]
17.

TransKingdom RNA interference: a bacterial approach to challenges in RNAi therapy and delivery.

Keates AC, Fruehauf J, Xiang S, Li CJ.

Biotechnol Genet Eng Rev. 2008;25:113-27. Review.

PMID:
21412352
[PubMed - indexed for MEDLINE]
18.

Primer extension-based method for the generation of a siRNA/miRNA expression vector.

Gou D, Zhang H, Baviskar PS, Liu L.

Physiol Genomics. 2007 Nov 14;31(3):554-62. Epub 2007 Sep 5.

PMID:
17804605
[PubMed - indexed for MEDLINE]
Free Article
19.

RNA interference and cancer therapy.

Wang Z, Rao DD, Senzer N, Nemunaitis J.

Pharm Res. 2011 Dec;28(12):2983-95. doi: 10.1007/s11095-011-0604-5. Epub 2011 Oct 19. Review.

PMID:
22009588
[PubMed - indexed for MEDLINE]
20.

Enhanced target gene knockdown by a bifunctional shRNA: a novel approach of RNA interference.

Rao DD, Maples PB, Senzer N, Kumar P, Wang Z, Pappen BO, Yu Y, Haddock C, Jay C, Phadke AP, Chen S, Kuhn J, Dylewski D, Scott S, Monsma D, Webb C, Tong A, Shanahan D, Nemunaitis J.

Cancer Gene Ther. 2010 Nov;17(11):780-91. doi: 10.1038/cgt.2010.35. Epub 2010 Jul 2.

PMID:
20596090
[PubMed - indexed for MEDLINE]

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