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Results: 1 to 20 of 212

1.

Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo.

He S, Iwashita T, Buchstaller J, Molofsky AV, Thomas D, Morrison SJ.

Dev Biol. 2009 Apr 15;328(2):257-72. doi: 10.1016/j.ydbio.2009.01.020. Epub 2009 Jan 27.

PMID:
19389366
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.

Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ.

Nature. 2003 Oct 30;425(6961):962-7. Epub 2003 Oct 22.

PMID:
14574365
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.

Molofsky AV, He S, Bydon M, Morrison SJ, Pardal R.

Genes Dev. 2005 Jun 15;19(12):1432-7.

PMID:
15964994
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma.

Bruggeman SW, Hulsman D, Tanger E, Buckle T, Blom M, Zevenhoven J, van Tellingen O, van Lohuizen M.

Cancer Cell. 2007 Oct;12(4):328-41.

PMID:
17936558
[PubMed - indexed for MEDLINE]
Free Article
5.

Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice.

Chiba T, Seki A, Aoki R, Ichikawa H, Negishi M, Miyagi S, Oguro H, Saraya A, Kamiya A, Nakauchi H, Yokosuka O, Iwama A.

Hepatology. 2010 Sep;52(3):1111-23. doi: 10.1002/hep.23793.

PMID:
20648475
[PubMed - indexed for MEDLINE]
6.

Conditional activation of Bmi1 expression regulates self-renewal, apoptosis, and differentiation of neural stem/progenitor cells in vitro and in vivo.

Yadirgi G, Leinster V, Acquati S, Bhagat H, Shakhova O, Marino S.

Stem Cells. 2011 Apr;29(4):700-12. doi: 10.1002/stem.614.

PMID:
21305672
[PubMed - indexed for MEDLINE]
Free Article
7.

Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain.

Fasano CA, Phoenix TN, Kokovay E, Lowry N, Elkabetz Y, Dimos JT, Lemischka IR, Studer L, Temple S.

Genes Dev. 2009 Mar 1;23(5):561-74. doi: 10.1101/gad.1743709.

PMID:
19270157
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion.

Michael LE, Westerman BA, Ermilov AN, Wang A, Ferris J, Liu J, Blom M, Ellison DW, van Lohuizen M, Dlugosz AA.

Neoplasia. 2008 Dec;10(12):1343-9, 5p following 1349.

PMID:
19048113
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells.

Wang L, Liu Z, Balivada S, Shrestha T, Bossmann S, Pyle M, Pappan L, Shi J, Troyer D.

Stem Cell Res Ther. 2012 Feb 10;3(1):5. doi: 10.1186/scrt96.

PMID:
22330721
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

Bruggeman SW, Valk-Lingbeek ME, van der Stoop PP, Jacobs JJ, Kieboom K, Tanger E, Hulsman D, Leung C, Arsenijevic Y, Marino S, van Lohuizen M.

Genes Dev. 2005 Jun 15;19(12):1438-43.

PMID:
15964995
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation.

Lukacs RU, Memarzadeh S, Wu H, Witte ON.

Cell Stem Cell. 2010 Dec 3;7(6):682-93. doi: 10.1016/j.stem.2010.11.013.

PMID:
21112563
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Bmi1 and cell of origin determinants of brain tumor phenotype.

Dirks P.

Cancer Cell. 2007 Oct;12(4):295-7.

PMID:
17936553
[PubMed - indexed for MEDLINE]
Free Article
13.

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo.

Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC.

Genes Dev. 2001 Aug 1;15(15):1913-25.

PMID:
11485986
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality.

Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng GS.

Mol Cell Biol. 2007 Oct;27(19):6706-17. Epub 2007 Jul 23.

PMID:
17646384
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.

Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ.

PLoS Genet. 2009 Jun;5(6):e1000511. doi: 10.1371/journal.pgen.1000511. Epub 2009 Jun 12.

PMID:
19521500
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Transgenic analysis of central nervous system development and regeneration.

Lendahl U.

Acta Anaesthesiol Scand Suppl. 1997;110:116-8.

PMID:
9248556
[PubMed - indexed for MEDLINE]
17.

Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci.

Zacharek SJ, Fillmore CM, Lau AN, Gludish DW, Chou A, Ho JW, Zamponi R, Gazit R, Bock C, Jäger N, Smith ZD, Kim TM, Saunders AH, Wong J, Lee JH, Roach RR, Rossi DJ, Meissner A, Gimelbrant AA, Park PJ, Kim CF.

Cell Stem Cell. 2011 Sep 2;9(3):272-81. doi: 10.1016/j.stem.2011.07.007.

PMID:
21885022
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Bmi1 deficient neural stem cells have increased integrin dependent adhesion to self-secreted matrix.

Bruggeman SW, Hulsman D, van Lohuizen M.

Biochim Biophys Acta. 2009 May;1790(5):351-60. doi: 10.1016/j.bbagen.2009.03.009. Epub 2009 Mar 16.

PMID:
19298843
[PubMed - indexed for MEDLINE]
Free Article
19.

The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells.

Park HJ, Kim JK, Jeon HM, Oh SY, Kim SH, Nam DH, Kim H.

Mol Cells. 2010 Nov;30(5):403-8. doi: 10.1007/s10059-010-0122-z. Epub 2010 Aug 31. Erratum in: Mol Cells. 2011 Feb ;31(2):199. Park, Myung-Jin [removed]; Soeda, Akio [removed].

PMID:
20814749
[PubMed - indexed for MEDLINE]
Free Article
20.

A novel embryonic nestin-expressing radial glia-like progenitor gives rise to zonally restricted olfactory and vomeronasal neurons.

Murdoch B, Roskams AJ.

J Neurosci. 2008 Apr 16;28(16):4271-82. doi: 10.1523/JNEUROSCI.5566-07.2008.

PMID:
18417707
[PubMed - indexed for MEDLINE]
Free Article

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