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Results: 1 to 20 of 236

Similar articles for PubMed (Select 19364644)

1.

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors.

Isakovic L, Saavedra OM, Llewellyn DB, Claridge S, Zhan L, Bernstein N, Vaisburg A, Elowe N, Petschner AJ, Rahil J, Beaulieu N, Gauthier F, MacLeod AR, Delorme D, Besterman JM, Wahhab A.

Bioorg Med Chem Lett. 2009 May 15;19(10):2742-6. doi: 10.1016/j.bmcl.2009.03.132. Epub 2009 Mar 28.

PMID:
19364644
2.

SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes.

Saavedra OM, Isakovic L, Llewellyn DB, Zhan L, Bernstein N, Claridge S, Raeppel F, Vaisburg A, Elowe N, Petschner AJ, Rahil J, Beaulieu N, MacLeod AR, Delorme D, Besterman JM, Wahhab A.

Bioorg Med Chem Lett. 2009 May 15;19(10):2747-51. doi: 10.1016/j.bmcl.2009.03.113. Epub 2009 Mar 28.

PMID:
19362833
4.
5.

Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1.

Castellano S, Kuck D, Sala M, Novellino E, Lyko F, Sbardella G.

J Med Chem. 2008 Apr 10;51(7):2321-5. doi: 10.1021/jm7015705. Epub 2008 Mar 18.

PMID:
18345608
7.
8.

Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase.

Vanek V, Budesínský M, Kabeleová P, Sanda M, Kozísek M, Hanclová I, Mládková J, Brynda J, Rosenberg I, Koutmos M, Garrow TA, Jirácek J.

J Med Chem. 2009 Jun 25;52(12):3652-65. doi: 10.1021/jm8015798.

9.

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation.

Kuck D, Singh N, Lyko F, Medina-Franco JL.

Bioorg Med Chem. 2010 Jan 15;18(2):822-9. doi: 10.1016/j.bmc.2009.11.050. Epub 2009 Nov 27.

PMID:
20006515
10.
11.

Rapid synthesis of new DNMT inhibitors derivatives of procainamide.

Halby L, Champion C, Sénamaud-Beaufort C, Ajjan S, Drujon T, Rajavelu A, Ceccaldi A, Jurkowska R, Lequin O, Nelson WG, Guy A, Jeltsch A, Guianvarc'h D, Ferroud C, Arimondo PB.

Chembiochem. 2012 Jan 2;13(1):157-65. doi: 10.1002/cbic.201100522. Epub 2011 Dec 14.

PMID:
22170584
12.

Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.

Singh N, Dueñas-González A, Lyko F, Medina-Franco JL.

ChemMedChem. 2009 May;4(5):792-9. doi: 10.1002/cmdc.200900017.

PMID:
19322801
13.

Synthesis of DNA dumbbell based inhibitors for the human DNA methyltransferase Dnmt1.

Kuch D, Schermelleh L, Manetto S, Leonhardt H, Carell T.

Angew Chem Int Ed Engl. 2008;47(8):1515-8. doi: 10.1002/anie.200702055. No abstract available.

PMID:
18203234
14.

[Effect of S-nucleosyl-L-homocysteines on the activity of DNA methylases].

Nikol'skaia II, Lopatina NG, Rekunova VN, Iurkevich AM, Debov SS.

Vopr Med Khim. 1978 Mar-Apr;24(2):252-5. Russian.

PMID:
351945
16.

Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na(+) channels with increased potency and improved use-dependent activity.

Franchini C, Corbo F, Lentini G, Bruno G, Scilimati A, Tortorella V, Conte Camerino D, De Luca A.

J Med Chem. 2000 Oct 5;43(20):3792-8.

PMID:
11020295
17.

Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors.

Conejo-García A, Campos JM, Sánchez-Martín RM, Gallo MA, Espinosa A.

J Med Chem. 2003 Aug 14;46(17):3754-7.

PMID:
12904080
18.

Design, synthesis and preliminary evaluation of novel pyrrolidine derivatives as matrix metalloproteinase inhibitors.

Cheng XC, Wang Q, Fang H, Tang W, Xu WF.

Eur J Med Chem. 2008 Oct;43(10):2130-9. doi: 10.1016/j.ejmech.2007.12.020. Epub 2007 Dec 31.

PMID:
18362041
19.

Stereoselective synthesis of (2S,3S,4R,5S)-5-methylpyrrolidine-3,4-diol derivatives that are highly selective alpha-L-fucosidase inhibitors.

Moreno-Vargas AJ, Carmona AT, Mora F, Vogel P, Robina I.

Chem Commun (Camb). 2005 Oct 21;(39):4949-51. Epub 2005 Sep 8.

PMID:
16205810
20.

Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors.

Suzuki T, Tanaka R, Hamada S, Nakagawa H, Miyata N.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):1124-7. doi: 10.1016/j.bmcl.2009.12.016. Epub 2009 Dec 21.

PMID:
20056538
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