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Results: 1 to 20 of 81

1.

Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation.

Ghosh B, Benyumov AO, Ghosh P, Jia Y, Avdulov S, Dahlberg PS, Peterson M, Smith K, Polunovsky VA, Bitterman PB, Wagner CR.

ACS Chem Biol. 2009 May 15;4(5):367-77. doi: 10.1021/cb9000475.

PMID:
19351181
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E.

Altmann M, Schmitz N, Berset C, Trachsel H.

EMBO J. 1997 Mar 3;16(5):1114-21.

PMID:
9118949
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation.

Li S, Jia Y, Jacobson B, McCauley J, Kratzke R, Bitterman PB, Wagner CR.

Mol Pharm. 2013 Feb 4;10(2):523-31. doi: 10.1021/mp300699d.

PMID:
23289910
[PubMed - indexed for MEDLINE]
4.

Dynamic and tissue-specific expression of eIF4E during zebrafish embryogenesis.

Fahrenkrug SC, Dahlquist MO, Clark KJ, Hackett PB.

Differentiation. 1999 Dec;65(4):191-201.

PMID:
10653355
[PubMed - indexed for MEDLINE]
5.

High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translation.

Mochizuki K, Oguro A, Ohtsu T, Sonenberg N, Nakamura Y.

RNA. 2005 Jan;11(1):77-89.

PMID:
15611299
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Development of biochemical assays for the identification of eIF4E-specific inhibitors.

Visco C, Perrera C, Thieffine S, Sirtori FR, D'Alessio R, Magnaghi P.

J Biomol Screen. 2012 Jun;17(5):581-92. doi: 10.1177/1087057112438554. Epub 2012 Mar 5.

PMID:
22392810
[PubMed - indexed for MEDLINE]
8.

Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer.

Yamashita S, Miyagi C, Fukada T, Kagara N, Che YS, Hirano T.

Nature. 2004 May 20;429(6989):298-302. Epub 2004 May 5.

PMID:
15129296
[PubMed - indexed for MEDLINE]
9.

Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae.

Cosentino GP, Schmelzle T, Haghighat A, Helliwell SB, Hall MN, Sonenberg N.

Mol Cell Biol. 2000 Jul;20(13):4604-13.

PMID:
10848587
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Eukaryotic initiation factor 4E variants alter the morphology, proliferation, and colony-formation properties of MDA-MB-435 cancer cells.

Goldson TM, Vielhauer G, Staub E, Miller S, Shim H, Hagedorn CH.

Mol Carcinog. 2007 Jan;46(1):71-84.

PMID:
17091471
[PubMed - indexed for MEDLINE]
11.

Regulation of cap-dependent translation by eIF4E inhibitory proteins.

Richter JD, Sonenberg N.

Nature. 2005 Feb 3;433(7025):477-80. Review.

PMID:
15690031
[PubMed - indexed for MEDLINE]
12.

Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins.

Niedzwiecka A, Marcotrigiano J, Stepinski J, Jankowska-Anyszka M, Wyslouch-Cieszynska A, Dadlez M, Gingras AC, Mak P, Darzynkiewicz E, Sonenberg N, Burley SK, Stolarski R.

J Mol Biol. 2002 Jun 7;319(3):615-35.

PMID:
12054859
[PubMed - indexed for MEDLINE]
13.

Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20.

Ptushkina M, von der Haar T, Vasilescu S, Frank R, Birkenhäger R, McCarthy JE.

EMBO J. 1998 Aug 17;17(16):4798-808.

PMID:
9707439
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Two zebrafish eIF4E family members are differentially expressed and functionally divergent.

Robalino J, Joshi B, Fahrenkrug SC, Jagus R.

J Biol Chem. 2004 Mar 12;279(11):10532-41. Epub 2003 Dec 29.

PMID:
14701818
[PubMed - indexed for MEDLINE]
Free Article
15.

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

Cho PF, Poulin F, Cho-Park YA, Cho-Park IB, Chicoine JD, Lasko P, Sonenberg N.

Cell. 2005 May 6;121(3):411-23.

PMID:
15882623
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

Modulation of eukaryotic mRNA stability via the cap-binding translation complex eIF4F.

Ramirez CV, Vilela C, Berthelot K, McCarthy JE.

J Mol Biol. 2002 May 10;318(4):951-62.

PMID:
12054793
[PubMed - indexed for MEDLINE]
18.

Sodium arsenite-induced inhibition of eukaryotic translation initiation factor 4E (eIF4E) results in cytotoxicity and cell death.

Othumpangat S, Kashon M, Joseph P.

Mol Cell Biochem. 2005 Nov;279(1-2):123-31.

PMID:
16283521
[PubMed - indexed for MEDLINE]
19.

Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1.

Hu J, Straub J, Xiao D, Singh SV, Yang HS, Sonenberg N, Vatsyayan J.

Cancer Res. 2007 Apr 15;67(8):3569-73.

PMID:
17440067
[PubMed - indexed for MEDLINE]
Free Article
20.

Regulation of translation initiation by the yeast eIF4E binding proteins is required for the pseudohyphal response.

Ibrahimo S, Holmes LE, Ashe MP.

Yeast. 2006 Oct-Nov;23(14-15):1075-88.

PMID:
17083129
[PubMed - indexed for MEDLINE]

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