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Pharmacological properties of a pore induced by raising intracellular Ca2+.

Faria RX, Reis RA, Casabulho CM, Alberto AV, de Farias FP, Henriques-Pons A, Alves LA.

Am J Physiol Cell Physiol. 2009 Jul;297(1):C28-42. doi: 10.1152/ajpcell.00476.2008. Epub 2009 Mar 25.


Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells.

Faria RX, Cascabulho CM, Reis RA, Alves LA.

Naunyn Schmiedebergs Arch Pharmacol. 2010 Jul;382(1):73-87. doi: 10.1007/s00210-010-0523-8. Epub 2010 May 28.


Are second messengers crucial for opening the pore associated with P2X7 receptor?

Faria RX, Defarias FP, Alves LA.

Am J Physiol Cell Physiol. 2005 Feb;288(2):C260-71. Epub 2004 Oct 6.


ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages.

Schachter J, Motta AP, de Souza Zamorano A, da Silva-Souza HA, Guimarães MZ, Persechini PM.

J Cell Sci. 2008 Oct 1;121(Pt 19):3261-70. doi: 10.1242/jcs.029991. Epub 2008 Sep 9.


Maitotoxin and P2Z/P2X(7) purinergic receptor stimulation activate a common cytolytic pore.

Schilling WP, Wasylyna T, Dubyak GR, Humphreys BD, Sinkins WG.

Am J Physiol. 1999 Oct;277(4 Pt 1):C766-76.


Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells.

Donnelly-Roberts DL, Namovic MT, Faltynek CR, Jarvis MF.

J Pharmacol Exp Ther. 2004 Mar;308(3):1053-61. Epub 2003 Nov 21.


cAMP potentiates ATP-evoked calcium signaling in human parotid acinar cells.

Brown DA, Bruce JI, Straub SV, Yule DI.

J Biol Chem. 2004 Sep 17;279(38):39485-94. Epub 2004 Jul 19.


Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line.

Takenouchi T, Ogihara K, Sato M, Kitani H.

Biochim Biophys Acta. 2005 Nov 15;1726(2):177-86. Epub 2005 Aug 15.


Pharmacological characterization of P2X7 receptors in rat peritoneal cells.

Chen YW, Donnelly-Roberts DL, Namovic MT, Gintant GA, Cox BF, Jarvis MF, Harris RR.

Inflamm Res. 2005 Mar;54(3):119-26.


Activation of P2Y receptors stimulates potassium and cation currents in acutely isolated human Müller (glial) cells.

Bringmann A, Pannicke T, Weick M, Biedermann B, Uhlmann S, Kohen L, Wiedemann P, Reichenbach A.

Glia. 2002 Feb;37(2):139-52.


A P2X7 receptor stimulates plasma membrane trafficking in the FRTL rat thyrocyte cell line.

Kochukov MY, Ritchie AK.

Am J Physiol Cell Physiol. 2004 Oct;287(4):C992-C1002. Epub 2004 Jun 9.


The nucleotide receptor P2X7 mediates actin reorganization and membrane blebbing in RAW 264.7 macrophages via p38 MAP kinase and Rho.

Pfeiffer ZA, Aga M, Prabhu U, Watters JJ, Hall DJ, Bertics PJ.

J Leukoc Biol. 2004 Jun;75(6):1173-82. Epub 2004 Apr 9.


Increase of intracellular Ca2+ by P2X and P2Y receptor-subtypes in cultured cortical astroglia of the rat.

Fischer W, Appelt K, Grohmann M, Franke H, Nörenberg W, Illes P.

Neuroscience. 2009 Jun 2;160(4):767-83. doi: 10.1016/j.neuroscience.2009.02.026. Epub 2009 Mar 13.


ATP induces intracellular calcium increases and actin cytoskeleton disaggregation via P2x receptors.

Pubill D, Dayanithi G, Siatka C, Andrés M, Dufour MN, Guillon G, Mendre C.

Cell Calcium. 2001 May;29(5):299-309.


Involvement of chloride in apoptotic cell death induced by activation of ATP-sensitive P2X7 purinoceptor.

Tsukimoto M, Harada H, Ikari A, Takagi K.

J Biol Chem. 2005 Jan 28;280(4):2653-8. Epub 2004 Nov 17.


P2X7 receptor activates multiple selective dye-permeation pathways in RAW 264.7 and human embryonic kidney 293 cells.

Cankurtaran-Sayar S, Sayar K, Ugur M.

Mol Pharmacol. 2009 Dec;76(6):1323-32. doi: 10.1124/mol.109.059923. Epub 2009 Sep 11.

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