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Items: 1 to 20 of 107

1.

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Assmann A, Ueki K, Winnay JN, Kadowaki T, Kulkarni RN.

Mol Cell Biol. 2009 Jun;29(11):3219-28. doi: 10.1128/MCB.01489-08. Epub 2009 Mar 9.

2.

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.

Venieratos PD, Drossopoulou GI, Kapodistria KD, Tsilibary EC, Kitsiou PV.

Cell Signal. 2010 May;22(5):791-800. doi: 10.1016/j.cellsig.2010.01.003. Epub 2010 Jan 11.

PMID:
20067833
3.

Effect of zinc on regulation of insulin-like growth factor signaling in human androgen-independent prostate cancer cells.

Banudevi S, Senthilkumar K, Sharmila G, Arunkumar R, Vijayababu MR, Arunakaran J.

Clin Chim Acta. 2010 Feb;411(3-4):172-8. doi: 10.1016/j.cca.2009.10.023. Epub 2009 Nov 11.

PMID:
19913001
4.

Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells.

Cahuana GM, Tejedo JR, Hmadcha A, Ramírez R, Cuesta AL, Soria B, Martin F, Bedoya FJ.

Cell Signal. 2008 Feb;20(2):301-10. Epub 2007 Oct 12.

PMID:
18023142
5.

Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway.

Subramaniam S, Shahani N, Strelau J, Laliberté C, Brandt R, Kaplan D, Unsicker K.

J Neurosci. 2005 Mar 16;25(11):2838-52.

8.

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.

Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.

Diabetes. 2002 Apr;51(4):966-76.

9.

PDGF- and insulin/IGF-1-specific distinct modes of class IA PI 3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells.

Biswas SK, Zhao Y, Nagalingam A, Gardner TW, Sandirasegarane L.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3687-98. doi: 10.1167/iovs.07-1455. Epub 2008 Apr 17.

PMID:
18421086
11.
12.

Increased IRS-2 content and activation of IGF-I pathway contribute to enhance beta-cell mass in fetuses from undernourished pregnant rats.

Fernández E, Martín MA, Fajardo S, Escrivá F, Alvarez C.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E187-95. Epub 2006 Aug 15.

13.
14.

Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).

Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG Jr, Rhodes CJ.

J Biol Chem. 2001 Jun 15;276(24):21110-20. Epub 2001 Mar 27.

15.

Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.

Conejo R, Lorenzo M.

J Cell Physiol. 2001 Apr;187(1):96-108.

PMID:
11241354
16.

Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action.

Fulzele K, DiGirolamo DJ, Liu Z, Xu J, Messina JL, Clemens TL.

J Biol Chem. 2007 Aug 31;282(35):25649-58. Epub 2007 Jun 6.

17.

Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines.

Shukla A, Grisouard J, Ehemann V, Hermani A, Enzmann H, Mayer D.

Endocr Relat Cancer. 2009 Jun;16(2):429-41. doi: 10.1677/ERC-08-0240. Epub 2009 Jan 19.

18.

Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

Wente W, Efanov AM, Brenner M, Kharitonenkov A, Köster A, Sandusky GE, Sewing S, Treinies I, Zitzer H, Gromada J.

Diabetes. 2006 Sep;55(9):2470-8.

19.

Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.

Mur C, Valverde AM, Kahn CR, Benito M.

Diabetes. 2002 Mar;51(3):743-54.

20.

Activin receptor-like kinase 7 induces apoptosis of pancreatic beta cells and beta cell lines.

Zhang N, Kumar M, Xu G, Ju W, Yoon T, Xu E, Huang X, Gaisano H, Peng C, Wang Q.

Diabetologia. 2006 Mar;49(3):506-18. Epub 2006 Jan 27.

PMID:
16440210
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