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Results: 1 to 20 of 98

1.

Optical visualization of Alzheimer's pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation.

Kwan AC, Duff K, Gouras GK, Webb WW.

Opt Express. 2009 Mar 2;17(5):3679-89.

PMID:
19259208
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases.

Wirths O, Bethge T, Marcello A, Harmeier A, Jawhar S, Lucassen PJ, Multhaup G, Brody DL, Esparza T, Ingelsson M, Kalimo H, Lannfelt L, Bayer TA.

J Neural Transm. 2010 Jan;117(1):85-96. doi: 10.1007/s00702-009-0314-x. Epub 2009 Oct 13.

PMID:
19823761
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer's disease.

McCarter JF, Liebscher S, Bachhuber T, Abou-Ajram C, Hübener M, Hyman BT, Haass C, Meyer-Luehmann M.

Acta Neuropathol. 2013 Aug;126(2):179-88. doi: 10.1007/s00401-013-1137-2. Epub 2013 Jun 18.

PMID:
23775142
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

MRI and histological analysis of beta-amyloid plaques in both human Alzheimer's disease and APP/PS1 transgenic mice.

Meadowcroft MD, Connor JR, Smith MB, Yang QX.

J Magn Reson Imaging. 2009 May;29(5):997-1007. doi: 10.1002/jmri.21731.

PMID:
19388095
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model.

Karuppagounder SS, Xu H, Shi Q, Chen LH, Pedrini S, Pechman D, Baker H, Beal MF, Gandy SE, Gibson GE.

Neurobiol Aging. 2009 Oct;30(10):1587-600. doi: 10.1016/j.neurobiolaging.2007.12.013. Epub 2008 Apr 10.

PMID:
18406011
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development.

Zhang XM, Cai Y, Xiong K, Cai H, Luo XG, Feng JC, Clough RW, Struble RG, Patrylo PR, Yan XX.

Eur J Neurosci. 2009 Dec;30(12):2271-83. doi: 10.1111/j.1460-9568.2009.07017.x. Epub 2009 Dec 10.

PMID:
20092570
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Preclinical characterization of amyloid imaging probes with multiphoton microscopy.

Skoch J, Hyman BT, Bacskai BJ.

J Alzheimers Dis. 2006;9(3 Suppl):401-7. Review.

PMID:
16914878
[PubMed - indexed for MEDLINE]
8.

Spatial frequency domain imaging of intrinsic optical property contrast in a mouse model of Alzheimer's disease.

Lin AJ, Koike MA, Green KN, Kim JG, Mazhar A, Rice TB, LaFerla FM, Tromberg BJ.

Ann Biomed Eng. 2011 Apr;39(4):1349-57. doi: 10.1007/s10439-011-0269-6. Epub 2011 Feb 19.

PMID:
21331663
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Monitoring protein aggregation and toxicity in Alzheimer's disease mouse models using in vivo imaging.

Spires-Jones TL, de Calignon A, Meyer-Luehmann M, Bacskai BJ, Hyman BT.

Methods. 2011 Mar;53(3):201-7. doi: 10.1016/j.ymeth.2010.12.009. Epub 2010 Dec 14.

PMID:
21163350
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Alzheimer's disease: what multiphoton microscopy teaches us.

Bacskai BJ, Hyman BT.

Neuroscientist. 2002 Oct;8(5):386-90. Review.

PMID:
12374422
[PubMed - indexed for MEDLINE]
11.

[Selected mice models based on APP, MAPT and presenilin gene mutations in research on the pathogenesis of Alzheimer's disease].

Więdłocha M, Stańczykiewicz B, Jakubik M, Rymaszewska J.

Postepy Hig Med Dosw (Online). 2012 Jun 22;66:415-30. Review. Polish.

PMID:
22922141
[PubMed - indexed for MEDLINE]
Free Article
12.

DNA base excision repair activities in mouse models of Alzheimer's disease.

Weissman L, de Souza-Pinto NC, Mattson MP, Bohr VA.

Neurobiol Aging. 2009 Dec;30(12):2080-1. doi: 10.1016/j.neurobiolaging.2008.02.014. Epub 2008 Apr 18.

PMID:
18378358
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Alzheimer's disease and amyloid: culprit or coincidence?

Skaper SD.

Int Rev Neurobiol. 2012;102:277-316. doi: 10.1016/B978-0-12-386986-9.00011-9. Review.

PMID:
22748834
[PubMed - indexed for MEDLINE]
14.

Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease.

Kukreja L, Kujoth GC, Prolla TA, Van Leuven F, Vassar R.

Mol Neurodegener. 2014 May 2;9:16. doi: 10.1186/1750-1326-9-16.

PMID:
24885175
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice.

Yan P, Bero AW, Cirrito JR, Xiao Q, Hu X, Wang Y, Gonzales E, Holtzman DM, Lee JM.

J Neurosci. 2009 Aug 26;29(34):10706-14. doi: 10.1523/JNEUROSCI.2637-09.2009.

PMID:
19710322
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Amyloid plaque and neurofibrillary tangle pathology in a regulatable mouse model of Alzheimer's disease.

Paulson JB, Ramsden M, Forster C, Sherman MA, McGowan E, Ashe KH.

Am J Pathol. 2008 Sep;173(3):762-72. doi: 10.2353/ajpath.2008.080175. Epub 2008 Jul 31.

PMID:
18669616
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer's disease mouse model.

Rozkalne A, Spires-Jones TL, Stern EA, Hyman BT.

Brain Res. 2009 Jul 14;1280:178-85. doi: 10.1016/j.brainres.2009.05.045. Epub 2009 May 22.

PMID:
19465012
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy.

McLellan ME, Kajdasz ST, Hyman BT, Bacskai BJ.

J Neurosci. 2003 Mar 15;23(6):2212-7.

PMID:
12657680
[PubMed - indexed for MEDLINE]
Free Article
19.

Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice.

Bacskai BJ, Hickey GA, Skoch J, Kajdasz ST, Wang Y, Huang GF, Mathis CA, Klunk WE, Hyman BT.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12462-7. Epub 2003 Sep 29.

PMID:
14517353
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Efficient near-infrared in vivo imaging of amyoid-β deposits in Alzheimer's disease mouse models.

Schmidt A, Pahnke J.

J Alzheimers Dis. 2012;30(3):651-64. doi: 10.3233/JAD-2012-112168.

PMID:
22460331
[PubMed - indexed for MEDLINE]

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