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19246719,24588637,18631348,21672055,23614768,24152160,25545270,17347497,20673978,21317378,25789608,26882889,24679471,12689651,16611648,20974988,23352232,19630858,23239494,20562264,31340811,31264384,20732990,20019337,31321783,24506934,23805294,21741880,16499650,22962064,24139608,23369007,19735273,25676669,20148421,17631139,23006545,29343807,24536057,22092967,32970964,15663556,17845408,19295236,29026003,22521241,21422039,18174546,17289654,23293351,15879422,28111308,21958117,17610940,12672065,19234107,21257225,16008685,16103687,21613618,25355927,29038008,23347053,22539286,24446518,20224068,22994367,25109604,25760938,24238232,23036747,28634005,14597485,27062360,29337391,14970180,21512170,27625307,23300949,18787221,28888782,27746238,28189772,30127088,33113503,34506849,27743410,25849971,26344079,26232935,24836003,26641462,23151845,14617509,27614844,25714839,28192144,27852745,19933379,24932688,27734946,24128591,24152048,29319845,30358441,17626835,23018133,20664577,25465099,33643284,27484038,30171721,29274414,23768572,19218814,25944053,32229377,20167851,21474346,24067878,28811323,25088053,26287681,20709826,28063042,15576672,25477068,17122383,26362930,25630305,23420883,25930193,26263242,26999446,21255010,27225906,33312170,24022125,24098413,27397923,25924733,23561801,23492189,18202345,27870920,21297073,21836154,22903968,12847273,15650773,27309732,20819925,31900344,22021618,24661094,30619373,23328530,25780046,23390295,30230272,15634935,23822145,21471101,16081811,30052281,29111212,16461338,32757273,20508067,21562124,29567318,11970998,27796360,32418317,24060272,19330007,25645346,26003185,20581096,26214807,28502093,15034070,24415780,30537285,33929099,22802353,24112543,24048894,26214396,27569535,12077275,19502389,23831627,21820713,17600276,31494992,28889953,35524325,25015831,9351586,25748065,17475846,26502779,26303344,21624504,30405619,27992060,31329326,30407865,30184256,17684332,34418187,19191902,31645649,31611876,29846732,21195789,19661246,27248433,11157058,32255764,28614408,24698321,20016195,25823227,27315767,26041536,23694705,30635238,10102639,12752600,27177781,12380787,22079492,16314437,34185416,26205779,27035878,35503474,32582180,23808363,31469599,26748611,28700253,17400732,28687462,25823713,16008674,25595789,24332592,26318911,31511356,17562814,31616416,24150243,28887522,30745361,32846422,26194936,24943219,21498664,36460835,25616105,33443037,24290277,31125592,12421921,28063044,23466989,26108570,32599580,30534125,24372635,22685525,15528378,31260596,31445933,33256981,33647226,18377768,24227776,34818549,31231035,19178937,25649077,26081441,29867994,18162718,29911993,25359462,20093792,28684329,27864285,20339149,35110420,31164097,24717780,29361942,25746967,19060952,23349887,29111218,29792201,26196219,28532656,29038036,26427878,29444897,30353972,28745029,12750407,31861989,23452076,29305916,26476732,31922608,27209052,24733846,16528012,26825674,36215676,33042124,26017186,27895167,33952618,29762870,25479722,26386119,26953647,26335962,26976823,35363997,24165907,26750312,25692509,31242493,27696462,26238189,24111738,20590919,25403892,28515363,24807637,31708110,23915187,25629767,22525013,10528218,32179158,25661808,27546168,25746970,22973560,26872695,36099784,12486107,33383090,29036225,20816550,28667161,35396219,21501148,20622028,27016609,34848868,19786548,12133980,17727569,29318574,30604629,19224641,24608645,16651610,18178860,34671116,17404323,33841934,29288652,21391988,32783616,18454155,27027965,23943452,19843690,30307073,23093652,24122358,32466530,25803300,25640055,23450108,34580428,24551140,21783420,27166557,17664287,15158630,28600286,33557842,30840481,22005301,18448455,26962188,18436652,28107345,22119406,29890236,18407534,16319345,23319328,32185817,32329078,26787865,26773141,30312497,27574298,17442966,29131267,21115733,24172848,25617148,17424888,25839234,23298698,33249168,31704734,9802985,30054206,19348928,35475923,28207927,17607007,26290411,12860930,24985082,26101328,27939673,33618285,31380805,19545261,30616774,27799314,22777483,17463415,23617587,26276007,32585675,27518660,28758900,27402277,22075698,25692703,22889845,27221135,31640701,26547707,19621025,30711489,17885690,28108561,28121465,24613091,21224214,31076879,22268141,26740570,33093516,24980659,25151003,28966255,35833903,23341605,33558372,33541260,29035391,21618506,30040973,36012669,34126986,25933166,30541898,28960101,33281825,35801505,34296788,27815425,24129160,12456639,24986626,35285025,24943330,27543676,17446336,23391720,21538995,28977706,19342693,23334847,21402950,21881572,31889961,19014484,26694221,33731828,26922672,33047743,25391140,16878598,21051864,30763933,17339484,30356799,33942458,36776398,21930963,36706056,16361354,20823152,25866971,28473323,25086171,26167753,36685549,12618421,25479317,19667087,33165810,29910811,17623648,28775364,33653328,24636086,16008676,25876764,33709404,28912627,25504013,30348735,33957164,15557163,25760420,26200013,26165408,30362569,26826245,16476192,31562870,24503582,31941986,31330218,19017983,18832692,17544833,25040758,35977797,1282180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Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses.

Phipps S, Lam CE, Kaiko GE, Foo SY, Collison A, Mattes J, Barry J, Davidson S, Oreo K, Smith L, Mansell A, Matthaei KI, Foster PS. Phipps S, et al. Am J Respir Crit Care Med. 2009 May 15;179(10):883-93. doi: 10.1164/rccm.200806-974OC. Epub 2009 Feb 26. Am J Respir Crit Care Med. 2009. PMID: 19246719

Dectin-2 promotes house dust mite-induced T helper type 2 and type 17 cell differentiation and allergic airway inflammation in mice.

Norimoto A, Hirose K, Iwata A, Tamachi T, Yokota M, Takahashi K, Saijo S, Iwakura Y, Nakajima H. Norimoto A, et al. Am J Respir Cell Mol Biol. 2014 Aug;51(2):201-9. doi: 10.1165/rcmb.2013-0522OC. Am J Respir Cell Mol Biol. 2014. PMID: 24588637

Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: role of MyD88 adaptor molecule and interleukin-12/interferon-gamma axis.

Bortolatto J, Borducchi E, Rodriguez D, Keller AC, Faquim-Mauro E, Bortoluci KR, Mucida D, Gomes E, Christ A, Schnyder-Candrian S, Schnyder B, Ryffel B, Russo M. Bortolatto J, et al. Clin Exp Allergy. 2008 Oct;38(10):1668-79. doi: 10.1111/j.1365-2222.2008.03036.x. Epub 2008 Jun 25. Clin Exp Allergy. 2008. PMID: 18631348

Bacillus-derived poly-γ-glutamic acid attenuates allergic airway inflammation through a Toll-like receptor-4-dependent pathway in a murine model of asthma.

Lee K, Kim SH, Yoon HJ, Paik DJ, Kim JM, Youn J. Lee K, et al. Clin Exp Allergy. 2011 Aug;41(8):1143-56. doi: 10.1111/j.1365-2222.2011.03792.x. Epub 2011 Jun 14. Clin Exp Allergy. 2011. PMID: 21672055

Absence of Toll-IL-1 receptor 8/single immunoglobulin IL-1 receptor-related molecule reduces house dust mite-induced allergic airway inflammation in mice.

Barry J, Loh Z, Collison A, Mazzone S, Lalwani A, Zhang V, Davidson S, Wybacz E, Garlanda C, Mantovani A, Mattes J, Foster PS, Phipps S. Barry J, et al. Am J Respir Cell Mol Biol. 2013 Sep;49(3):481-90. doi: 10.1165/rcmb.2012-0425OC. Am J Respir Cell Mol Biol. 2013. PMID: 23614768

Proteinase-activated receptor-2 activation participates in allergic sensitization to house dust mite allergens in a murine model.

Davidson CE, Asaduzzaman M, Arizmendi NG, Polley D, Wu Y, Gordon JR, Hollenberg MD, Cameron L, Vliagoftis H. Davidson CE, et al. Clin Exp Allergy. 2013 Nov;43(11):1274-85. doi: 10.1111/cea.12185. Clin Exp Allergy. 2013. PMID: 24152160

OX40 blockade inhibits house dust mite driven allergic lung inflammation in mice and in vitro allergic responses in humans.

Burrows KE, Dumont C, Thompson CL, Catley MC, Dixon KL, Marshall D. Burrows KE, et al. Eur J Immunol. 2015 Apr;45(4):1116-28. doi: 10.1002/eji.201445163. Epub 2015 Jan 21. Eur J Immunol. 2015. PMID: 25545270 Free article.

Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation.

Gomes B, Cabral MD, Gallard A, Savignac M, Paulet P, Druet P, Mariamé B, Moreau M, Leclerc C, Guéry JC, Pelletier L. Gomes B, et al. Am J Respir Crit Care Med. 2007 Jun 1;175(11):1117-24. doi: 10.1164/rccm.200607-1026OC. Epub 2007 Mar 8. Am J Respir Crit Care Med. 2007. PMID: 17347497

Interferon response factor 3 is essential for house dust mite-induced airway allergy.

Marichal T, Bedoret D, Mesnil C, Pichavant M, Goriely S, Trottein F, Cataldo D, Goldman M, Lekeux P, Bureau F, Desmet CJ. Marichal T, et al. J Allergy Clin Immunol. 2010 Oct;126(4):836-844.e13. doi: 10.1016/j.jaci.2010.06.009. Epub 2010 Jul 31. J Allergy Clin Immunol. 2010. PMID: 20673978

Cigarette smoke differentially affects eosinophilia and remodeling in a model of house dust mite asthma.

Botelho FM, Llop-Guevara A, Trimble NJ, Nikota JK, Bauer CM, Lambert KN, Kianpour S, Jordana M, Stämpfli MR. Botelho FM, et al. Am J Respir Cell Mol Biol. 2011 Oct;45(4):753-60. doi: 10.1165/rcmb.2010-0404OC. Epub 2011 Feb 11. Am J Respir Cell Mol Biol. 2011. PMID: 21317378

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