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Results: 1 to 20 of 291

1.

Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion.

Ussher JR, Lopaschuk GD.

Basic Res Cardiol. 2009 Mar;104(2):203-10. doi: 10.1007/s00395-009-0003-9. Epub 2009 Feb 26. Review.

PMID:
19242641
[PubMed - indexed for MEDLINE]
2.

The malonyl CoA axis as a potential target for treating ischaemic heart disease.

Ussher JR, Lopaschuk GD.

Cardiovasc Res. 2008 Jul 15;79(2):259-68. doi: 10.1093/cvr/cvn130. Epub 2008 May 22. Review.

PMID:
18499682
[PubMed - indexed for MEDLINE]
Free Article
3.

Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.

Dyck JR, Cheng JF, Stanley WC, Barr R, Chandler MP, Brown S, Wallace D, Arrhenius T, Harmon C, Yang G, Nadzan AM, Lopaschuk GD.

Circ Res. 2004 May 14;94(9):e78-84. Epub 2004 Apr 22.

PMID:
15105298
[PubMed - indexed for MEDLINE]
Free Article
4.

Malonyl CoA control of fatty acid oxidation in the ischemic heart.

Dyck JR, Lopaschuk GD.

J Mol Cell Cardiol. 2002 Sep;34(9):1099-109. Review.

PMID:
12392882
[PubMed - indexed for MEDLINE]
5.

Malonyl-CoA decarboxylase inhibition as a novel approach to treat ischemic heart disease.

Lopaschuk GD, Stanley WC.

Cardiovasc Drugs Ther. 2006 Dec;20(6):433-9. Review.

PMID:
17136490
[PubMed - indexed for MEDLINE]
6.

AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart.

Hopkins TA, Dyck JR, Lopaschuk GD.

Biochem Soc Trans. 2003 Feb;31(Pt 1):207-12. Review.

PMID:
12546686
[PubMed - indexed for MEDLINE]
8.

Fatty acid oxidation in the reperfused ischemic heart.

Kantor PF, Dyck JR, Lopaschuk GD.

Am J Med Sci. 1999 Jul;318(1):3-14. Review.

PMID:
10408755
[PubMed - indexed for MEDLINE]
9.

Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation.

Zhou L, Huang H, Yuan CL, Keung W, Lopaschuk GD, Stanley WC.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H954-60. Epub 2007 Dec 14.

PMID:
18083904
[PubMed - indexed for MEDLINE]
Free Article
10.

Alterations in fatty acid oxidation during reperfusion of the heart after myocardial ischemia.

Lopaschuk GD.

Am J Cardiol. 1997 Aug 4;80(3A):11A-16A. Review.

PMID:
9293951
[PubMed - indexed for MEDLINE]
11.

Regulation of cardiac malonyl-CoA content and fatty acid oxidation during increased cardiac power.

King KL, Okere IC, Sharma N, Dyck JR, Reszko AE, McElfresh TA, Kerner J, Chandler MP, Lopaschuk GD, Stanley WC.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1033-7. Epub 2005 Apr 8.

PMID:
15821035
[PubMed - indexed for MEDLINE]
Free Article
12.

Carnitine palmitoyltransferase in cardiac ischemia. A potential site for altered fatty acid metabolism.

Pauly DF, Kirk KA, McMillin JB.

Circ Res. 1991 Apr;68(4):1085-94.

PMID:
2009609
[PubMed - indexed for MEDLINE]
Free Article
13.

Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply.

Onay-Besikci A, Sambandam N.

Can J Physiol Pharmacol. 2006 Nov;84(11):1215-22.

PMID:
17218986
[PubMed - indexed for MEDLINE]
14.

Acetyl-CoA carboxylase involvement in the rapid maturation of fatty acid oxidation in the newborn rabbit heart.

Lopaschuk GD, Witters LA, Itoi T, Barr R, Barr A.

J Biol Chem. 1994 Oct 14;269(41):25871-8.

PMID:
7929291
[PubMed - indexed for MEDLINE]
Free Article
15.

Malonyl-CoA decarboxylase is a major regulator of myocardial fatty acid oxidation.

Cuthbert KD, Dyck JR.

Curr Hypertens Rep. 2005 Dec;7(6):407-11. Review.

PMID:
16386195
[PubMed - indexed for MEDLINE]
16.

Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels.

Hall JL, Lopaschuk GD, Barr A, Bringas J, Pizzurro RD, Stanley WC.

Cardiovasc Res. 1996 Nov;32(5):879-85.

PMID:
8944819
[PubMed - indexed for MEDLINE]
Free Article
17.

Characterization of cardiac malonyl-CoA decarboxylase and its putative role in regulating fatty acid oxidation.

Dyck JR, Barr AJ, Barr RL, Kolattukudy PE, Lopaschuk GD.

Am J Physiol. 1998 Dec;275(6 Pt 2):H2122-9.

PMID:
9843812
[PubMed - indexed for MEDLINE]
Free Article
19.

Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis.

Atkinson LL, Fischer MA, Lopaschuk GD.

J Biol Chem. 2002 Aug 16;277(33):29424-30. Epub 2002 Jun 10.

PMID:
12058043
[PubMed - indexed for MEDLINE]
Free Article
20.

Malonyl-CoA decarboxylase inhibition suppresses fatty acid oxidation and reduces lactate production during demand-induced ischemia.

Stanley WC, Morgan EE, Huang H, McElfresh TA, Sterk JP, Okere IC, Chandler MP, Cheng J, Dyck JR, Lopaschuk GD.

Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2304-9. Epub 2005 Aug 12.

PMID:
16100246
[PubMed - indexed for MEDLINE]
Free Article

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