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Results: 1 to 20 of 139

1.

An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation.

Chang YY, Neufeld TP.

Mol Biol Cell. 2009 Apr;20(7):2004-14. doi: 10.1091/mbc.E08-12-1250. Epub 2009 Feb 18.

PMID:
19225150
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy.

Stephan JS, Yeh YY, Ramachandran V, Deminoff SJ, Herman PK.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17049-54. doi: 10.1073/pnas.0903316106. Epub 2009 Sep 21.

PMID:
19805182
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

PMID:
22885598
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase.

Lee SB, Kim S, Lee J, Park J, Lee G, Kim Y, Kim JM, Chung J.

EMBO Rep. 2007 Apr;8(4):360-5. Epub 2007 Mar 9.

PMID:
17347671
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

Mercer CA, Kaliappan A, Dennis PB.

Autophagy. 2009 Jul;5(5):649-62. Epub 2009 Jul 20.

PMID:
19287211
[PubMed - indexed for MEDLINE]
Free Article
6.

Tor directly controls the Atg1 kinase complex to regulate autophagy.

Kamada Y, Yoshino K, Kondo C, Kawamata T, Oshiro N, Yonezawa K, Ohsumi Y.

Mol Cell Biol. 2010 Feb;30(4):1049-58. doi: 10.1128/MCB.01344-09. Epub 2009 Dec 7.

PMID:
19995911
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila.

Juhász G, Hill JH, Yan Y, Sass M, Baehrecke EH, Backer JM, Neufeld TP.

J Cell Biol. 2008 May 19;181(4):655-66. doi: 10.1083/jcb.200712051. Epub 2008 May 12.

PMID:
18474623
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.

Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH.

Mol Biol Cell. 2009 Apr;20(7):1992-2003. doi: 10.1091/mbc.E08-12-1249. Epub 2009 Feb 18.

PMID:
19225151
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death.

Scott RC, Juhász G, Neufeld TP.

Curr Biol. 2007 Jan 9;17(1):1-11.

PMID:
17208179
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The ATG1/ATG13 protein kinase complex is both a regulator and a target of autophagic recycling in Arabidopsis.

Suttangkakul A, Li F, Chung T, Vierstra RD.

Plant Cell. 2011 Oct;23(10):3761-79. doi: 10.1105/tpc.111.090993. Epub 2011 Oct 7.

PMID:
21984698
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Nutrient-dependent regulation of autophagy through the target of rapamycin pathway.

Chang YY, Juhász G, Goraksha-Hicks P, Arsham AM, Mallin DR, Muller LK, Neufeld TP.

Biochem Soc Trans. 2009 Feb;37(Pt 1):232-6. doi: 10.1042/BST0370232. Review.

PMID:
19143638
[PubMed - indexed for MEDLINE]
13.

Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy.

Kabeya Y, Kamada Y, Baba M, Takikawa H, Sasaki M, Ohsumi Y.

Mol Biol Cell. 2005 May;16(5):2544-53. Epub 2005 Mar 2.

PMID:
15743910
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

Activation of Atg1 kinase in autophagy by regulated phosphorylation.

Kijanska M, Dohnal I, Reiter W, Kaspar S, Stoffel I, Ammerer G, Kraft C, Peter M.

Autophagy. 2010 Nov;6(8):1168-78. Epub 2010 Nov 16.

PMID:
20953146
[PubMed - indexed for MEDLINE]
Free Article
16.

An Atg13 protein-mediated self-association of the Atg1 protein kinase is important for the induction of autophagy.

Yeh YY, Shah KH, Herman PK.

J Biol Chem. 2011 Aug 19;286(33):28931-9. doi: 10.1074/jbc.M111.250324. Epub 2011 Jun 28.

PMID:
21712380
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N.

Mol Biol Cell. 2009 Apr;20(7):1981-91. doi: 10.1091/mbc.E08-12-1248. Epub 2009 Feb 11.

PMID:
19211835
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Contribution of Atg1-dependent autophagy to TOR-mediated cell growth and survival.

Neufeld TP.

Autophagy. 2007 Sep-Oct;3(5):477-9. Epub 2007 Apr 26.

PMID:
17525525
[PubMed - indexed for MEDLINE]
Free Article
19.

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.

Chan EY, Longatti A, McKnight NC, Tooze SA.

Mol Cell Biol. 2009 Jan;29(1):157-71. doi: 10.1128/MCB.01082-08. Epub 2008 Oct 20.

PMID:
18936157
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Autophosphorylation within the Atg1 activation loop is required for both kinase activity and the induction of autophagy in Saccharomyces cerevisiae.

Yeh YY, Wrasman K, Herman PK.

Genetics. 2010 Jul;185(3):871-82. doi: 10.1534/genetics.110.116566. Epub 2010 May 3.

PMID:
20439775
[PubMed - indexed for MEDLINE]
Free PMC Article

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