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Results: 1 to 20 of 137

1.

Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.

Shen HC, He M, Powell A, Adem A, Lorang D, Heller C, Grover AC, Ylaya K, Hewitt SM, Marx SJ, Spiegel AM, Libutti SK.

Cancer Res. 2009 Mar 1;69(5):1858-66. doi: 10.1158/0008-5472.CAN-08-3662. Epub 2009 Feb 10.

PMID:
19208834
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Accelerated proliferation and differential global gene expression in pancreatic islets of five-week-old heterozygous Men1 mice: Men1 is a haploinsufficient suppressor.

Lejonklou MH, Barbu A, Stålberg P, Skogseid B.

Endocrinology. 2012 Jun;153(6):2588-98. doi: 10.1210/en.2011-1924. Epub 2012 Apr 4.

PMID:
22492302
[PubMed - indexed for MEDLINE]
3.

Multiple endocrine neoplasia type 1.

Agarwal SK.

Front Horm Res. 2013;41:1-15. doi: 10.1159/000345666. Epub 2013 Mar 19. Review.

PMID:
23652667
[PubMed - indexed for MEDLINE]
4.

A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors.

Crabtree JS, Scacheri PC, Ward JM, Garrett-Beal L, Emmert-Buck MR, Edgemon KA, Lorang D, Libutti SK, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS.

Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1118-23.

PMID:
11158604
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The embryonic transcription factor Hlxb9 is a menin interacting partner that controls pancreatic β-cell proliferation and the expression of insulin regulators.

Shi K, Parekh VI, Roy S, Desai SS, Agarwal SK.

Endocr Relat Cancer. 2013 Feb 18;20(1):111-22. doi: 10.1530/ERC-12-0077. Print 2013 Feb.

PMID:
23419452
[PubMed - indexed for MEDLINE]
Free Article
6.

Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia.

Harding B, Lemos MC, Reed AA, Walls GV, Jeyabalan J, Bowl MR, Tateossian H, Sullivan N, Hough T, Fraser WD, Ansorge O, Cheeseman MT, Thakker RV.

Endocr Relat Cancer. 2009 Dec;16(4):1313-27. doi: 10.1677/ERC-09-0082. Epub 2009 Jul 20.

PMID:
19620250
[PubMed - indexed for MEDLINE]
Free Article
7.

Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1.

Loffler KA, Biondi CA, Gartside M, Waring P, Stark M, Serewko-Auret MM, Muller HK, Hayward NK, Kay GF.

Int J Cancer. 2007 Jan 15;120(2):259-67.

PMID:
17044021
[PubMed - indexed for MEDLINE]
8.

The gene for multiple endocrine neoplasia type 1: recent findings.

Marx SJ, Agarwal SK, Heppner C, Kim YS, Kester MB, Goldsmith PK, Skarulis MC, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Emmert-Buck MR, Guru SC, Manickam P, Crabtree JS, Collins FS, Chandrasekharappa SC.

Bone. 1999 Jul;25(1):119-22. Review.

PMID:
10423035
[PubMed - indexed for MEDLINE]
9.

Proliferation rates of multiple endocrine neoplasia type 1 (MEN1)-associated tumors.

Walls GV, Reed AA, Jeyabalan J, Javid M, Hill NR, Harding B, Thakker RV.

Endocrinology. 2012 Nov;153(11):5167-79. doi: 10.1210/en.2012-1675. Epub 2012 Sep 28.

PMID:
23024266
[PubMed - indexed for MEDLINE]
10.

Genome-wide characterization of menin-dependent H3K4me3 reveals a specific role for menin in the regulation of genes implicated in MEN1-like tumors.

Agarwal SK, Jothi R.

PLoS One. 2012;7(5):e37952. doi: 10.1371/journal.pone.0037952. Epub 2012 May 30.

PMID:
22666422
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1.

Bertolino P, Tong WM, Galendo D, Wang ZQ, Zhang CX.

Mol Endocrinol. 2003 Sep;17(9):1880-92. Epub 2003 Jun 20.

PMID:
12819299
[PubMed - indexed for MEDLINE]
12.

Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene.

Lemos MC, Thakker RV.

Hum Mutat. 2008 Jan;29(1):22-32. Review.

PMID:
17879353
[PubMed - indexed for MEDLINE]
13.

[The role and mechanism of high expression of cyclin B2 in MEN1 insulinoma].

Wu T, Huang XH.

Sheng Li Xue Bao. 2011 Dec 25;63(6):555-64. Chinese.

PMID:
22193451
[PubMed - indexed for MEDLINE]
Free Article
14.

Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome.

Dilley WG, Kalyanaraman S, Verma S, Cobb JP, Laramie JM, Lairmore TC.

Mol Cancer. 2005 Feb 3;4(1):9.

PMID:
15691381
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases.

Corbo V, Dalai I, Scardoni M, Barbi S, Beghelli S, Bersani S, Albarello L, Doglioni C, Schott C, Capelli P, Chilosi M, Boninsegna L, Becker KF, Falconi M, Scarpa A.

Endocr Relat Cancer. 2010 Aug 16;17(3):771-83. doi: 10.1677/ERC-10-0028. Print 2010 Sep.

PMID:
20566584
[PubMed - indexed for MEDLINE]
Free Article
16.

Multiple microvascular alterations in pancreatic islets and neuroendocrine tumors of a Men1 mouse model.

Chu X, Gao X, Jansson L, Quach M, Skogseid B, Barbu A.

Am J Pathol. 2013 Jun;182(6):2355-67. doi: 10.1016/j.ajpath.2013.02.023. Epub 2013 Apr 12.

PMID:
23583653
[PubMed - indexed for MEDLINE]
Free Article
17.

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.

Scacheri PC, Davis S, Odom DT, Crawford GE, Perkins S, Halawi MJ, Agarwal SK, Marx SJ, Spiegel AM, Meltzer PS, Collins FS.

PLoS Genet. 2006 Apr;2(4):e51. Epub 2006 Apr 7.

PMID:
16604156
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Analysis of p27(Kip1) expression in insulinomas developed in pancreatic beta-cell specific Men1 mutant mice.

Fontanière S, Casse H, Bertolino P, Zhang CX.

Fam Cancer. 2006;5(1):49-54.

PMID:
16528608
[PubMed - indexed for MEDLINE]
19.

Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias.

Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Skarulis MC, James LA, Goldsmith PK, Saggar SK, Park SY, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Emmert-Buck MR, Guru SC, Manickam P, Crabtree J, Erdos MR, Collins FS, Chandrasekharappa SC.

Recent Prog Horm Res. 1999;54:397-438; discussion 438-9. Review.

PMID:
10548885
[PubMed - indexed for MEDLINE]
20.

Haploinsufficient and predominant expression of multiple endocrine neoplasia type 1 (MEN1)-related genes, MLL, p27Kip1 and p18Ink4C in endocrine organs.

Taguchi R, Yamada M, Horiguchi K, Tomaru T, Ozawa A, Shibusawa N, Hashimoto K, Okada S, Satoh T, Mori M.

Biochem Biophys Res Commun. 2011 Nov 18;415(2):378-83. doi: 10.1016/j.bbrc.2011.10.077. Epub 2011 Oct 21.

PMID:
22037578
[PubMed - indexed for MEDLINE]

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