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Results: 1 to 20 of 133

1.

Mutant copper-zinc superoxide dismutase associated with amyotrophic lateral sclerosis binds to adenine/uridine-rich stability elements in the vascular endothelial growth factor 3'-untranslated region.

Li X, Lu L, Bush DJ, Zhang X, Zheng L, Suswam EA, King PH.

J Neurochem. 2009 Feb;108(4):1032-44. doi: 10.1111/j.1471-4159.2008.05856.x.

PMID:
19196430
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-transcriptional regulation of vascular endothelial growth factor.

Lu L, Wang S, Zheng L, Li X, Suswam EA, Zhang X, Wheeler CG, Nabors LB, Filippova N, King PH.

J Biol Chem. 2009 Dec 4;284(49):33989-98. doi: 10.1074/jbc.M109.067918. Epub 2009 Oct 5.

PMID:
19805546
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression.

Lu L, Zheng L, Viera L, Suswam E, Li Y, Li X, Estévez AG, King PH.

J Neurosci. 2007 Jul 25;27(30):7929-38.

PMID:
17652584
[PubMed - indexed for MEDLINE]
Free Article
4.

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).

Volkening K, Leystra-Lantz C, Yang W, Jaffee H, Strong MJ.

Brain Res. 2009 Dec 11;1305:168-82. doi: 10.1016/j.brainres.2009.09.105. Epub 2009 Oct 6.

PMID:
19815002
[PubMed - indexed for MEDLINE]
5.
6.

Posttranscriptional regulation of SOD1 gene expression under oxidative stress: Potential role of ELAV proteins in sporadic ALS.

Milani P, Amadio M, Laforenza U, Dell'Orco M, Diamanti L, Sardone V, Gagliardi S, Govoni S, Ceroni M, Pascale A, Cereda C.

Neurobiol Dis. 2013 Dec;60:51-60. doi: 10.1016/j.nbd.2013.08.005. Epub 2013 Aug 20.

PMID:
23969235
[PubMed - indexed for MEDLINE]
7.
8.

VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death.

Li B, Xu W, Luo C, Gozal D, Liu R.

Brain Res Mol Brain Res. 2003 Mar 17;111(1-2):155-64.

PMID:
12654515
[PubMed - indexed for MEDLINE]
9.

Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.

Lu L, Zheng L, Si Y, Luo W, Dujardin G, Kwan T, Potochick NR, Thompson SR, Schneider DA, King PH.

J Biol Chem. 2014 Nov 14;289(46):31792-804. doi: 10.1074/jbc.M114.573246. Epub 2014 Sep 19.

PMID:
25239623
[PubMed - indexed for MEDLINE]
10.

Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice.

Lelie HL, Liba A, Bourassa MW, Chattopadhyay M, Chan PK, Gralla EB, Miller LM, Borchelt DR, Valentine JS, Whitelegge JP.

J Biol Chem. 2011 Jan 28;286(4):2795-806. doi: 10.1074/jbc.M110.186999. Epub 2010 Nov 10.

PMID:
21068388
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis.

Watanabe S, Nagano S, Duce J, Kiaei M, Li QX, Tucker SM, Tiwari A, Brown RH Jr, Beal MF, Hayward LJ, Culotta VC, Yoshihara S, Sakoda S, Bush AI.

Free Radic Biol Med. 2007 May 15;42(10):1534-42. Epub 2007 Feb 15.

PMID:
17448900
[PubMed - indexed for MEDLINE]
12.

ALS-causing SOD1 mutations promote production of copper-deficient misfolded species.

Ip P, Mulligan VK, Chakrabartty A.

J Mol Biol. 2011 Jun 24;409(5):839-52. doi: 10.1016/j.jmb.2011.04.027. Epub 2011 Apr 27.

PMID:
21549128
[PubMed - indexed for MEDLINE]
13.

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.

Oh YK, Shin KS, Yuan J, Kang SJ.

J Neurochem. 2008 Feb;104(4):993-1005. doi: 10.1111/j.1471-4159.2007.05053.x.

PMID:
18233996
[PubMed - indexed for MEDLINE]
14.

Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.

Galaleldeen A, Strange RW, Whitson LJ, Antonyuk SV, Narayana N, Taylor AB, Schuermann JP, Holloway SP, Hasnain SS, Hart PJ.

Arch Biochem Biophys. 2009 Dec;492(1-2):40-7. doi: 10.1016/j.abb.2009.09.020. Epub 2009 Oct 1.

PMID:
19800308
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.

Li QX, Mok SS, Laughton KM, McLean CA, Volitakis I, Cherny RA, Cheung NS, White AR, Masters CL.

Aging Cell. 2006 Apr;5(2):153-65.

PMID:
16626394
[PubMed - indexed for MEDLINE]
16.

Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis.

Tiwari A, Xu Z, Hayward LJ.

J Biol Chem. 2005 Aug 19;280(33):29771-9. Epub 2005 Jun 15.

PMID:
15958382
[PubMed - indexed for MEDLINE]
Free Article
17.

Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice.

Pan L, Yoshii Y, Otomo A, Ogawa H, Iwasaki Y, Shang HF, Hadano S.

PLoS One. 2012;7(3):e33409. doi: 10.1371/journal.pone.0033409. Epub 2012 Mar 16.

PMID:
22438926
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Stabilization of mutant Cu/Zn superoxide dismutase (SOD1) protein by coexpressed wild SOD1 protein accelerates the disease progression in familial amyotrophic lateral sclerosis mice.

Fukada K, Nagano S, Satoh M, Tohyama C, Nakanishi T, Shimizu A, Yanagihara T, Sakoda S.

Eur J Neurosci. 2001 Dec;14(12):2032-6.

PMID:
11860498
[PubMed - indexed for MEDLINE]
19.

Immunodetection of disease-associated conformers of mutant cu/zn superoxide dismutase 1 selectively expressed in degenerating neurons in amyotrophic lateral sclerosis.

Sábado J, Casanovas A, Hernández S, Piedrafita L, Hereu M, Esquerda JE.

J Neuropathol Exp Neurol. 2013 Jul;72(7):646-61. doi: 10.1097/NEN.0b013e318297fd10.

PMID:
23771221
[PubMed - indexed for MEDLINE]
20.

Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury.

Goos M, Zech WD, Jaiswal MK, Balakrishnan S, Ebert S, Mitchell T, Carrì MT, Keller BU, Nau R.

BMC Infect Dis. 2007 Nov 12;7:131.

PMID:
17997855
[PubMed - indexed for MEDLINE]
Free PMC Article
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