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Items: 1 to 20 of 307

1.

Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization.

Merlet J, Burger J, Gomes JE, Pintard L.

Cell Mol Life Sci. 2009 Jun;66(11-12):1924-38. doi: 10.1007/s00018-009-8712-7. Review.

PMID:
19194658
2.

Protection of cullin-RING E3 ligases by CSN-UBP12.

Wu JT, Chan YR, Chien CT.

Trends Cell Biol. 2006 Jul;16(7):362-9. Epub 2006 Jun 9. Review.

PMID:
16762551
3.

Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome.

Menon S, Tsuge T, Dohmae N, Takio K, Wei N.

BMC Biochem. 2008 Jan 3;9:1. doi: 10.1186/1471-2091-9-1.

4.

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

Kurz T, Ozlü N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M.

Nature. 2005 Jun 30;435(7046):1257-61.

PMID:
15988528
5.

Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization.

Chew EH, Poobalasingam T, Hawkey CJ, Hagen T.

Cell Signal. 2007 May;19(5):1071-80. Epub 2006 Dec 16.

PMID:
17254749
6.

Drosophila Cand1 regulates Cullin3-dependent E3 ligases by affecting the neddylation of Cullin3 and by controlling the stability of Cullin3 and adaptor protein.

Kim SH, Kim HJ, Kim S, Yim J.

Dev Biol. 2010 Oct 15;346(2):247-57. doi: 10.1016/j.ydbio.2010.07.031. Epub 2010 Aug 4.

7.

Neddylation-induced conformational control regulates cullin RING ligase activity in vivo.

Boh BK, Smith PG, Hagen T.

J Mol Biol. 2011 Jun 3;409(2):136-45. doi: 10.1016/j.jmb.2011.03.023. Epub 2011 Apr 2.

PMID:
21463634
8.

Substrate-mediated regulation of cullin neddylation.

Chew EH, Hagen T.

J Biol Chem. 2007 Jun 8;282(23):17032-40. Epub 2007 Apr 17.

9.

Cullin-RING ubiquitin ligases: global regulation and activation cycles.

Bosu DR, Kipreos ET.

Cell Div. 2008 Feb 18;3:7. doi: 10.1186/1747-1028-3-7.

10.

Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activity.

Choo YY, Boh BK, Lou JJ, Eng J, Leck YC, Anders B, Smith PG, Hagen T.

Mol Biol Cell. 2011 Dec;22(24):4706-15. doi: 10.1091/mbc.E11-03-0251. Epub 2011 Oct 19.

11.

Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation.

Wu JT, Lin HC, Hu YC, Chien CT.

Nat Cell Biol. 2005 Oct;7(10):1014-20. Epub 2005 Aug 28.

PMID:
16127432
12.

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.

Duda DM, Borg LA, Scott DC, Hunt HW, Hammel M, Schulman BA.

Cell. 2008 Sep 19;134(6):995-1006. doi: 10.1016/j.cell.2008.07.022.

13.

Structural regulation of cullin-RING ubiquitin ligase complexes.

Duda DM, Scott DC, Calabrese MF, Zimmerman ES, Zheng N, Schulman BA.

Curr Opin Struct Biol. 2011 Apr;21(2):257-64. doi: 10.1016/j.sbi.2011.01.003. Epub 2011 Feb 1. Review.

14.

Building and remodelling Cullin-RING E3 ubiquitin ligases.

Lydeard JR, Schulman BA, Harper JW.

EMBO Rep. 2013 Dec;14(12):1050-61. doi: 10.1038/embor.2013.173. Epub 2013 Nov 15. Review.

15.

Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer.

Soucy TA, Smith PG, Rolfe M.

Clin Cancer Res. 2009 Jun 15;15(12):3912-6. doi: 10.1158/1078-0432.CCR-09-0343. Epub 2009 Jun 9.

16.

Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation.

Kurz T, Chou YC, Willems AR, Meyer-Schaller N, Hecht ML, Tyers M, Peter M, Sicheri F.

Mol Cell. 2008 Jan 18;29(1):23-35. doi: 10.1016/j.molcel.2007.12.012.

17.

Nedd8 on cullin: building an expressway to protein destruction.

Pan ZQ, Kentsis A, Dias DC, Yamoah K, Wu K.

Oncogene. 2004 Mar 15;23(11):1985-97. Review.

PMID:
15021886
18.

The COP9 signalosome and its role in plant development.

Schwechheimer C, Isono E.

Eur J Cell Biol. 2010 Feb-Mar;89(2-3):157-62. doi: 10.1016/j.ejcb.2009.11.021. Epub 2009 Dec 24. Review.

PMID:
20036030
19.

SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.

Kim AY, Bommeljé CC, Lee BE, Yonekawa Y, Choi L, Morris LG, Huang G, Kaufman A, Ryan RJ, Hao B, Ramanathan Y, Singh B.

J Biol Chem. 2008 Nov 28;283(48):33211-20. doi: 10.1074/jbc.M804440200. Epub 2008 Sep 30.

20.

A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin.

Willems AR, Schwab M, Tyers M.

Biochim Biophys Acta. 2004 Nov 29;1695(1-3):133-70. Review.

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