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Items: 1 to 20 of 130

1.

Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes.

Nakahara M, Sonoda E, Nojima K, Sale JE, Takenaka K, Kikuchi K, Taniguchi Y, Nakamura K, Sumitomo Y, Bree RT, Lowndes NF, Takeda S.

PLoS Genet. 2009 Jan;5(1):e1000356. doi: 10.1371/journal.pgen.1000356. Epub 2009 Jan 30.

2.

DNA polymerases nu and theta are required for efficient immunoglobulin V gene diversification in chicken.

Kohzaki M, Nishihara K, Hirota K, Sonoda E, Yoshimura M, Ekino S, Butler JE, Watanabe M, Halazonetis TD, Takeda S.

J Cell Biol. 2010 Jun 28;189(7):1117-27. doi: 10.1083/jcb.200912012.

3.

The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions.

Yabuki M, Fujii MM, Maizels N.

Nat Immunol. 2005 Jul;6(7):730-6. Epub 2005 Jun 5.

PMID:
15937485
4.

Bloom DNA helicase facilitates homologous recombination between diverged homologous sequences.

Kikuchi K, Abdel-Aziz HI, Taniguchi Y, Yamazoe M, Takeda S, Hirota K.

J Biol Chem. 2009 Sep 25;284(39):26360-7. doi: 10.1074/jbc.M109.029348. Epub 2009 Aug 5.

5.

Brca1 in immunoglobulin gene conversion and somatic hypermutation.

Longerich S, Orelli BJ, Martin RW, Bishop DK, Storb U.

DNA Repair (Amst). 2008 Feb 1;7(2):253-66. Epub 2007 Nov 26.

6.

Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair.

Nakamura K, Kogame T, Oshiumi H, Shinohara A, Sumitomo Y, Agama K, Pommier Y, Tsutsui KM, Tsutsui K, Hartsuiker E, Ogi T, Takeda S, Taniguchi Y.

PLoS Genet. 2010 Jan 22;6(1):e1000828. doi: 10.1371/journal.pgen.1000828.

7.

Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis.

Kawamoto T, Araki K, Sonoda E, Yamashita YM, Harada K, Kikuchi K, Masutani C, Hanaoka F, Nozaki K, Hashimoto N, Takeda S.

Mol Cell. 2005 Dec 9;20(5):793-9.

8.
9.

Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation.

Sale JE, Calandrini DM, Takata M, Takeda S, Neuberger MS.

Nature. 2001 Aug 30;412(6850):921-6.

PMID:
11528482
10.

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells.

Tauchi H, Kobayashi J, Morishima K, van Gent DC, Shiraishi T, Verkaik NS, vanHeems D, Ito E, Nakamura A, Sonoda E, Takata M, Takeda S, Matsuura S, Komatsu K.

Nature. 2002 Nov 7;420(6911):93-8.

PMID:
12422221
11.

Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination.

Farah JA, Cromie GA, Smith GR.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9356-61. doi: 10.1073/pnas.0902793106. Epub 2009 May 22.

12.

MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification.

Larson ED, Cummings WJ, Bednarski DW, Maizels N.

Mol Cell. 2005 Nov 11;20(3):367-75.

13.

Immunoglobulin gene conversion or hypermutation: that's the question.

Buerstedde JM, Arakawa H.

Subcell Biochem. 2006;40:11-24. Review.

PMID:
17623897
14.

Temporal regulation of Ig gene diversification revealed by single-cell imaging.

Ordinario EC, Yabuki M, Larson RP, Maizels N.

J Immunol. 2009 Oct 1;183(7):4545-53. doi: 10.4049/jimmunol.0900673. Epub 2009 Sep 11.

15.

The BRCT domain of PARP-1 is required for immunoglobulin gene conversion.

Paddock MN, Buelow BD, Takeda S, Scharenberg AM.

PLoS Biol. 2010 Jul 20;8(7):e1000428. doi: 10.1371/journal.pbio.1000428.

16.

CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination.

Falck J, Forment JV, Coates J, Mistrik M, Lukas J, Bartek J, Jackson SP.

EMBO Rep. 2012 Jun;13(6):561-8. doi: 10.1038/embor.2012.58.

17.

Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex.

Hsu HM, Wang HC, Chen ST, Hsu GC, Shen CY, Yu JC.

Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):2024-32.

18.

MRE11 complex links RECQ5 helicase to sites of DNA damage.

Zheng L, Kanagaraj R, Mihaljevic B, Schwendener S, Sartori AA, Gerrits B, Shevelev I, Janscak P.

Nucleic Acids Res. 2009 May;37(8):2645-57. doi: 10.1093/nar/gkp147. Epub 2009 Mar 6.

19.

DNA end resection by CtIP and exonuclease 1 prevents genomic instability.

Eid W, Steger M, El-Shemerly M, Ferretti LP, Peña-Diaz J, König C, Valtorta E, Sartori AA, Ferrari S.

EMBO Rep. 2010 Dec;11(12):962-8. doi: 10.1038/embor.2010.157. Epub 2010 Nov 5.

20.

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

Yun MH, Hiom K.

Nature. 2009 May 21;459(7245):460-3. doi: 10.1038/nature07955. Epub 2009 Apr 8.

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