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Results: 1 to 20 of 99

Related Citations for PubMed (Select 19165925)

1.

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.

McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ, Xavier RJ.

Nat Genet. 2008 Sep;40(9):1107-12. doi: 10.1038/ng.215.

2.

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease.

Brest P, Lapaquette P, Souidi M, Lebrigand K, Cesaro A, Vouret-Craviari V, Mari B, Barbry P, Mosnier JF, Hébuterne X, Harel-Bellan A, Mograbi B, Darfeuille-Michaud A, Hofman P.

Nat Genet. 2011 Mar;43(3):242-5. doi: 10.1038/ng.762. Epub 2011 Jan 30.

PMID:
21278745
3.

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.

Prescott NJ, Dominy KM, Kubo M, Lewis CM, Fisher SA, Redon R, Huang N, Stranger BE, Blaszczyk K, Hudspith B, Parkes G, Hosono N, Yamazaki K, Onnie CM, Forbes A, Dermitzakis ET, Nakamura Y, Mansfield JC, Sanderson J, Hurles ME, Roberts RG, Mathew CG.

Hum Mol Genet. 2010 May 1;19(9):1828-39. doi: 10.1093/hmg/ddq041. Epub 2010 Jan 27.

4.

IRGM variants and susceptibility to inflammatory bowel disease in the German population.

Glas J, Seiderer J, Bues S, Stallhofer J, Fries C, Olszak T, Tsekeri E, Wetzke M, Beigel F, Steib C, Friedrich M, Göke B, Diegelmann J, Czamara D, Brand S.

PLoS One. 2013;8(1):e54338. doi: 10.1371/journal.pone.0054338. Epub 2013 Jan 24.

5.

Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children.

Amre DK, Mack DR, Morgan K, Krupoves A, Costea I, Lambrette P, Grimard G, Dong J, Feguery H, Bucionis V, Deslandres C, Levy E, Seidman EG.

Inflamm Bowel Dis. 2009 Apr;15(4):501-7. doi: 10.1002/ibd.20785.

PMID:
18985712
6.

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.

Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC; Wellcome Trust Case Control Consortium, Cardon L, Mathew CG.

Nat Genet. 2007 Jul;39(7):830-2. Epub 2007 Jun 6.

7.

Is there a role for Crohn's disease-associated autophagy genes ATG16L1 and IRGM in formation of granulomas?

Wolfkamp SC, Te Velde AA, Weersma RK, Ponsioen CY, Stokkers PC.

Eur J Gastroenterol Hepatol. 2010 Aug;22(8):933-7. doi: 10.1097/MEG.0b013e32833775e6.

PMID:
20395867
8.

Autophagy and Crohn's disease.

Nguyen HT, Lapaquette P, Bringer MA, Darfeuille-Michaud A.

J Innate Immun. 2013;5(5):434-43. doi: 10.1159/000345129. Epub 2013 Jan 15. Review.

PMID:
23328432
9.

Association between variants of the autophagy related gene--IRGM and susceptibility to Crohn's disease and ulcerative colitis: a meta-analysis.

Lu XC, Tao Y, Wu C, Zhao PL, Li K, Zheng JY, Li LX.

PLoS One. 2013 Nov 13;8(11):e80602. doi: 10.1371/journal.pone.0080602. eCollection 2013.

10.

Associations between genetic variants in the IRGM gene and inflammatory bowel diseases in the Korean population.

Moon CM, Shin DJ, Kim SW, Son NH, Park A, Park B, Jung ES, Kim ES, Hong SP, Kim TI, Kim WH, Cheon JH.

Inflamm Bowel Dis. 2013 Jan;19(1):106-14. doi: 10.1002/ibd.22972.

PMID:
22508677
11.

Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in autophagy-related genes (GOIA study II).

Durães C, Machado JC, Portela F, Rodrigues S, Lago P, Cravo M, Ministro P, Marques M, Cremers I, Freitas J, Cotter J, Tavares L, Matos L, Medeiros I, Sousa R, Ramos J, Deus J, Caldeira P, Chagas C, Duarte MA, Gonçalves R, Loureiro R, Barros L, Bastos I, Cancela E, Moraes MC, Moreira MJ, Vieira AI, Magro F.

Inflamm Bowel Dis. 2013 Feb;19(2):230-9. doi: 10.1002/ibd.23007.

PMID:
22573572
12.

Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohn's disease.

Brain O, Cooney R, Simmons A, Jewell D.

Inflamm Bowel Dis. 2012 Apr;18(4):778-81. doi: 10.1002/ibd.21832. Epub 2011 Aug 9. Review.

PMID:
21830281
13.

Risk predisposition for Crohn disease: a "ménage à trois" combining IRGM allele, miRNA and xenophagy.

Brest P, Lapaquette P, Mograbi B, Darfeuille-Michaud A, Hofman P.

Autophagy. 2011 Jul;7(7):786-7. Epub 2011 Jul 1.

14.
15.

On the level: IRGM gene function is all about expression.

Huett A, McCarroll SA, Daly MJ, Xavier RJ.

Autophagy. 2009 Jan;5(1):96-9. Epub 2009 Jan 25.

16.

Mutations in IRGM are associated with more frequent need for surgery in patients with ileocolonic Crohn's disease.

Sehgal R, Berg A, Polinski JI, Hegarty JP, Lin Z, McKenna KJ, Stewart DB, Poritz LS, Koltun WA.

Dis Colon Rectum. 2012 Feb;55(2):115-21. doi: 10.1097/DCR.0b013e31823ccea8.

PMID:
22228152
17.

Polymorphism of the IRGM gene might predispose to fistulizing behavior in Crohn's disease.

Latiano A, Palmieri O, Cucchiara S, Castro M, D'Incà R, Guariso G, Dallapiccola B, Valvano MR, Latiano T, Andriulli A, Annese V.

Am J Gastroenterol. 2009 Jan;104(1):110-6. doi: 10.1038/ajg.2008.3.

PMID:
19098858
18.

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress.

Hoefkens E, Nys K, John JM, Van Steen K, Arijs I, Van der Goten J, Van Assche G, Agostinis P, Rutgeerts P, Vermeire S, Cleynen I.

Autophagy. 2013 Dec;9(12):2046-55. doi: 10.4161/auto.26337. Epub 2013 Nov 14.

PMID:
24247223
19.

Human IRGM gene "to be or not to be".

Bekpen C, Xavier RJ, Eichler EE.

Semin Immunopathol. 2010 Dec;32(4):437-44. doi: 10.1007/s00281-010-0224-x. Epub 2010 Aug 25. Review.

PMID:
20737271
20.

Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.

Yang SK, Hong M, Zhao W, Jung Y, Baek J, Tayebi N, Kim KM, Ye BD, Kim KJ, Park SH, Lee I, Lee EJ, Kim WH, Cheon JH, Kim YH, Jang BI, Kim HS, Choi JH, Koo JS, Lee JH, Jung SA, Lee YJ, Jang JY, Shin HD, Kang D, Youn HS, Liu J, Song K.

Gut. 2014 Jan;63(1):80-7. doi: 10.1136/gutjnl-2013-305193. Epub 2013 Jul 14.

PMID:
23850713
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