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Results: 1 to 20 of 66

1.

Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis.

Nagarajan P, Onami TM, Rajagopalan S, Kania S, Donnell R, Venkatachalam S.

Oncogene. 2009 Feb 26;28(8):1053-62. doi: 10.1038/onc.2008.440. Epub 2009 Jan 12.

PMID:
19137022
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Chromodomain helicase DNA-binding protein 2 affects the repair of X-ray and UV-induced DNA damage.

Rajagopalan S, Nepa J, Venkatachalam S.

Environ Mol Mutagen. 2012 Jan;53(1):44-50. doi: 10.1002/em.20674. Epub 2011 Aug 29.

PMID:
22223433
[PubMed - indexed for MEDLINE]
3.

Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.

Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW, Xu Y.

Mol Cell Biol. 2005 Jan;25(2):661-70.

PMID:
15632067
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility.

Celeste A, Difilippantonio S, Difilippantonio MJ, Fernandez-Capetillo O, Pilch DR, Sedelnikova OA, Eckhaus M, Ried T, Bonner WM, Nussenzweig A.

Cell. 2003 Aug 8;114(3):371-83.

PMID:
12914701
[PubMed - indexed for MEDLINE]
Free Article
5.

A mutation in the mouse Chd2 chromatin remodeling enzyme results in a complex renal phenotype.

Marfella CG, Henninger N, LeBlanc SE, Krishnan N, Garlick DS, Holzman LB, Imbalzano AN.

Kidney Blood Press Res. 2008;31(6):421-32. doi: 10.1159/000190788. Epub 2009 Jan 14.

PMID:
19142019
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1.

Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y.

Mol Cell Biol. 2010 Nov;30(22):5335-47. doi: 10.1128/MCB.00350-10. Epub 2010 Sep 13.

PMID:
20837706
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mutation of the SNF2 family member Chd2 affects mouse development and survival.

Marfella CG, Ohkawa Y, Coles AH, Garlick DS, Jones SN, Imbalzano AN.

J Cell Physiol. 2006 Oct;209(1):162-71. Erratum in: J Cell Physiol. 2007 Aug;212(2):562.

PMID:
16810678
[PubMed - indexed for MEDLINE]
8.

The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage.

Smeenk G, Wiegant WW, Vrolijk H, Solari AP, Pastink A, van Attikum H.

J Cell Biol. 2010 Sep 6;190(5):741-9. doi: 10.1083/jcb.201001048. Epub 2010 Aug 30.

PMID:
20805320
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.

Savic V, Yin B, Maas NL, Bredemeyer AL, Carpenter AC, Helmink BA, Yang-Iott KS, Sleckman BP, Bassing CH.

Mol Cell. 2009 May 15;34(3):298-310. doi: 10.1016/j.molcel.2009.04.012.

PMID:
19450528
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Functional interplay of p53 and Mus81 in DNA damage responses and cancer.

Pamidi A, Cardoso R, Hakem A, Matysiak-Zablocki E, Poonepalli A, Tamblyn L, Perez-Ordonez B, Hande MP, Sanchez O, Hakem R.

Cancer Res. 2007 Sep 15;67(18):8527-35.

PMID:
17875692
[PubMed - indexed for MEDLINE]
Free Article
11.

Disruption of chromodomain helicase DNA binding protein 2 (CHD2) causes scoliosis.

Kulkarni S, Nagarajan P, Wall J, Donovan DJ, Donell RL, Ligon AH, Venkatachalam S, Quade BJ.

Am J Med Genet A. 2008 May 1;146A(9):1117-27. doi: 10.1002/ajmg.a.32178.

PMID:
18386809
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.

An J, Huang YC, Xu QZ, Zhou LJ, Shang ZF, Huang B, Wang Y, Liu XD, Wu DC, Zhou PK.

BMC Mol Biol. 2010 Mar 6;11:18. doi: 10.1186/1471-2199-11-18.

PMID:
20205745
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

Morales M, Theunissen JW, Kim CF, Kitagawa R, Kastan MB, Petrini JH.

Genes Dev. 2005 Dec 15;19(24):3043-54.

PMID:
16357220
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Tissue-specific DNA-PK-dependent H2AX phosphorylation and gamma-H2AX elimination after X-irradiation in vivo.

Koike M, Sugasawa J, Yasuda M, Koike A.

Biochem Biophys Res Commun. 2008 Nov 7;376(1):52-5. doi: 10.1016/j.bbrc.2008.08.095. Epub 2008 Aug 26.

PMID:
18755145
[PubMed - indexed for MEDLINE]
15.

Involvement of mammalian Mus81 in genome integrity and tumor suppression.

McPherson JP, Lemmers B, Chahwan R, Pamidi A, Migon E, Matysiak-Zablocki E, Moynahan ME, Essers J, Hanada K, Poonepalli A, Sanchez-Sweatman O, Khokha R, Kanaar R, Jasin M, Hande MP, Hakem R.

Science. 2004 Jun 18;304(5678):1822-6.

PMID:
15205536
[PubMed - indexed for MEDLINE]
Free Article
16.

Generation of a rat monoclonal antibody specific for CHD2.

Harada A, Yoshimura S, Odawara J, Azuma M, Okada S, Nakamura M, Tachibana T, Ohkawa Y.

Hybridoma (Larchmt). 2010 Apr;29(2):173-7. doi: 10.1089/hyb.2009.0090.

PMID:
20443711
[PubMed - indexed for MEDLINE]
17.

Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.

Moon SH, Lin L, Zhang X, Nguyen TA, Darlington Y, Waldman AS, Lu X, Donehower LA.

J Biol Chem. 2010 Apr 23;285(17):12935-47. doi: 10.1074/jbc.M109.071696. Epub 2010 Jan 29.

PMID:
20118229
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

DNA double-strand breaks and gamma-H2AX signaling in the testis.

Hamer G, Roepers-Gajadien HL, van Duyn-Goedhart A, Gademan IS, Kal HB, van Buul PP, de Rooij DG.

Biol Reprod. 2003 Feb;68(2):628-34.

PMID:
12533428
[PubMed - indexed for MEDLINE]
Free Article
19.

p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals.

Vempati RK, Jayani RS, Notani D, Sengupta A, Galande S, Haldar D.

J Biol Chem. 2010 Sep 10;285(37):28553-64. doi: 10.1074/jbc.M110.149393. Epub 2010 Jun 29.

PMID:
20587414
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity.

Bassing CH, Alt FW.

Cell Cycle. 2004 Feb;3(2):149-53. Review.

PMID:
14712078
[PubMed - indexed for MEDLINE]
Free Article

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