Format
Items per page
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 203

1.

Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells.

Santoriello C, Deflorian G, Pezzimenti F, Kawakami K, Lanfrancone L, d'Adda di Fagagna F, Mione M.

Dis Model Mech. 2009 Jan-Feb;2(1-2):56-67. doi: 10.1242/dmm.001016. Epub 2008 Dec 22.

2.

Differential oncogenic Ras signaling and senescence in tumor cells.

Bihani T, Mason DX, Jackson TJ, Chen SC, Boettner B, Lin AW.

Cell Cycle. 2004 Sep;3(9):1201-7. Epub 2004 Sep 5.

PMID:
15492501
3.

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

Sarkisian CJ, Keister BA, Stairs DB, Boxer RB, Moody SE, Chodosh LA.

Nat Cell Biol. 2007 May;9(5):493-505. Epub 2007 Apr 22.

PMID:
17450133
4.

Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction.

Takaoka M, Harada H, Deramaudt TB, Oyama K, Andl CD, Johnstone CN, Rhoades B, Enders GH, Opitz OG, Nakagawa H.

Oncogene. 2004 Sep 2;23(40):6760-8.

PMID:
15273725
5.

Noonan, Costello and cardio-facio-cutaneous syndromes: dysregulation of the Ras-MAPK pathway.

Tidyman WE, Rauen KA.

Expert Rev Mol Med. 2008 Dec 9;10:e37. doi: 10.1017/S1462399408000902. Review.

PMID:
19063751
6.

Costello syndrome and related disorders.

Quezada E, Gripp KW.

Curr Opin Pediatr. 2007 Dec;19(6):636-44.

PMID:
18025929
7.

[Molecular genetic diagnostics in syndromes associated with the RAS/MAPK signalling pathway].

Molven A, Søvik O, von der Lippe C, Steine SJ, Njølstad PR, Houge G, Prescott TE.

Tidsskr Nor Laegeforen. 2009 Nov 19;129(22):2358-61. doi: 10.4045/tidsskr.09.0267. Norwegian.

8.

HRAS and the Costello syndrome.

Rauen KA.

Clin Genet. 2007 Feb;71(2):101-8. Review.

PMID:
17250658
9.

Oncogene-induced senescence as an initial barrier in lymphoma development.

Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dörken B, Jenuwein T, Schmitt CA.

Nature. 2005 Aug 4;436(7051):660-5.

10.

Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis.

Minamino T, Yoshida T, Tateno K, Miyauchi H, Zou Y, Toko H, Komuro I.

Circulation. 2003 Nov 4;108(18):2264-9. Epub 2003 Oct 13.

11.

Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line.

Zongaro S, de Stanchina E, Colombo T, D'Incalci M, Giulotto E, Mondello C.

Cancer Res. 2005 Dec 15;65(24):11411-8.

12.

Costello syndrome H-Ras alleles regulate cortical development.

Paquin A, Hordo C, Kaplan DR, Miller FD.

Dev Biol. 2009 Jun 15;330(2):440-51. doi: 10.1016/j.ydbio.2009.04.010. Epub 2009 Apr 14.

13.

A Proteomic approach for protein-profiling the oncogenic ras induced transformation (H-, K-, and N-Ras) in NIH/3T3 mouse embryonic fibroblasts.

Kim S, Lee YZ, Kim YS, Bahk YY.

Proteomics. 2008 Aug;8(15):3082-93. doi: 10.1002/pmic.200800106.

PMID:
18601226
14.

Cre/loxP-regulated transgenic zebrafish model for neural progenitor-specific oncogenic Kras expression.

Seok SH, Na YR, Han JH, Kim TH, Jung H, Lee BH, Emelyanov A, Parinov S, Park JH.

Cancer Sci. 2010 Jan;101(1):149-54. doi: 10.1111/j.1349-7006.2009.01393.x. Epub 2009 Oct 10.

15.

PPP1CA contributes to the senescence program induced by oncogenic Ras.

Castro ME, Ferrer I, Cascón A, Guijarro MV, Lleonart M, Ramón y Cajal S, Leal JF, Robledo M, Carnero A.

Carcinogenesis. 2008 Mar;29(3):491-9. doi: 10.1093/carcin/bgm246. Epub 2008 Jan 19.

16.

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T.

Cancer Cell. 2004 Apr;5(4):375-87.

17.

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders.

Aoki Y, Niihori T, Narumi Y, Kure S, Matsubara Y.

Hum Mutat. 2008 Aug;29(8):992-1006. doi: 10.1002/humu.20748. Review.

PMID:
18470943
18.

Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation.

Konishi H, Karakas B, Abukhdeir AM, Lauring J, Gustin JP, Garay JP, Konishi Y, Gallmeier E, Bachman KE, Park BH.

Cancer Res. 2007 Sep 15;67(18):8460-7.

19.

HRAS mutants identified in Costello syndrome patients can induce cellular senescence: possible implications for the pathogenesis of Costello syndrome.

Niihori T, Aoki Y, Okamoto N, Kurosawa K, Ohashi H, Mizuno S, Kawame H, Inazawa J, Ohura T, Arai H, Nabatame S, Kikuchi K, Kuroki Y, Miura M, Tanaka T, Ohtake A, Omori I, Ihara K, Mabe H, Watanabe K, Niijima S, Okano E, Numabe H, Matsubara Y.

J Hum Genet. 2011 Oct;56(10):707-15. doi: 10.1038/jhg.2011.85. Epub 2011 Aug 18.

PMID:
21850009
20.

A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.

Schuhmacher AJ, Guerra C, Sauzeau V, Cañamero M, Bustelo XR, Barbacid M.

J Clin Invest. 2008 Jun;118(6):2169-79. doi: 10.1172/JCI34385.

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk