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Results: 1 to 20 of 76

Similar articles for PubMed (Select 19128485)

1.

Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue.

Chène P, Rudloff J, Schoepfer J, Furet P, Meier P, Qian Z, Schlaeppi JM, Schmitz R, Radimerski T.

BMC Chem Biol. 2009 Jan 7;9:1. doi: 10.1186/1472-6769-9-1.

2.

Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors.

Jensen LH, Thougaard AV, Grauslund M, Søkilde B, Carstensen EV, Dvinge HK, Scudiero DA, Jensen PB, Shoemaker RH, Sehested M.

Cancer Res. 2005 Aug 15;65(16):7470-7.

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Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part I.

Furet P, Schoepfer J, Radimerski T, Chène P.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4014-7. doi: 10.1016/j.bmcl.2009.06.034. Epub 2009 Jun 13.

PMID:
19560355
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Podophyllotoxin aza-analogue, a novel DNA topoisomerase II inhibitor.

Iida A, Kano M, Kubota Y, Koga K, Tomioka K.

Chem Pharm Bull (Tokyo). 2000 Apr;48(4):486-9.

PMID:
10783066
9.

NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors.

Onda T, Toyoda E, Miyazaki O, Seno C, Kagaya S, Okamoto K, Nishikawa K.

Cancer Lett. 2008 Jan 18;259(1):99-110. Epub 2007 Nov 12.

PMID:
17998154
10.

Catalytic topoisomerase II inhibitors in cancer therapy.

Larsen AK, Escargueil AE, Skladanowski A.

Pharmacol Ther. 2003 Aug;99(2):167-81. Review.

PMID:
12888111
11.

A novel homogenous assay for topoisomerase II action and inhibition.

Jahnz M, Medina MA, Schwille P.

Chembiochem. 2005 May;6(5):920-6.

PMID:
15812853
12.

Modulation of radiation response by inhibiting topoisomerase II catalytic activity.

Mateos S, Hajji N, Pastor N, Cortés F.

Mutat Res. 2006 Jul 25;599(1-2):105-15. Epub 2006 Mar 30.

PMID:
16574164
13.

Thanatop: a novel 5-nitrofuran that is a highly active, cell-permeable inhibitor of topoisomerase II.

Polycarpou-Schwarz M, Müller K, Denger S, Riddell A, Lewis J, Gannon F, Reid G.

Cancer Res. 2007 May 1;67(9):4451-8.

14.

Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells.

Yang SY, Jia XZ, Feng LY, Li SY, An GS, Ni JH, Jia HT.

Biochem Pharmacol. 2009 Feb 1;77(3):433-43. doi: 10.1016/j.bcp.2008.10.022. Epub 2008 Oct 28.

PMID:
19014910
15.

Ellagic acid and polyhydroxylated urolithins are potent catalytic inhibitors of human topoisomerase II: an in vitro study.

Furlanetto V, Zagotto G, Pasquale R, Moro S, Gatto B.

J Agric Food Chem. 2012 Sep 12;60(36):9162-70. doi: 10.1021/jf302600q. Epub 2012 Sep 4.

PMID:
22924519
16.

The QTK loop is essential for the communication between the N-terminal atpase domain and the central cleavage--ligation region in human topoisomerase IIalpha.

Bendsen S, Oestergaard VH, Skouboe C, Brinch M, Knudsen BR, Andersen AH.

Biochemistry. 2009 Jul 14;48(27):6508-15. doi: 10.1021/bi9005978.

PMID:
19485418
17.

Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationships.

Charifson PS, Grillot AL, Grossman TH, Parsons JD, Badia M, Bellon S, Deininger DD, Drumm JE, Gross CH, LeTiran A, Liao Y, Mani N, Nicolau DP, Perola E, Ronkin S, Shannon D, Swenson LL, Tang Q, Tessier PR, Tian SK, Trudeau M, Wang T, Wei Y, Zhang H, Stamos D.

J Med Chem. 2008 Sep 11;51(17):5243-63. doi: 10.1021/jm800318d. Epub 2008 Aug 9.

PMID:
18690678
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Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy.

Martin E, Thougaard AV, Grauslund M, Jensen PB, Bjorkling F, Hasinoff BB, Tjørnelund J, Sehested M, Jensen LH.

Toxicology. 2009 Jan 8;255(1-2):72-9. doi: 10.1016/j.tox.2008.10.011. Epub 2008 Oct 25.

PMID:
19010377
20.

Synthesis, cytotoxic activity, DNA topoisomerase-II inhibition, molecular modeling and structure-activity relationship of 9-anilinothiazolo[5,4-b]quinoline derivatives.

Loza-Mejía MA, Olvera-Vázquez S, Maldonado-Hernández K, Guadarrama-Salgado T, González-Sánchez I, Rodríguez-Hernández F, Solano JD, Rodríguez-Sotres R, Lira-Rocha A.

Bioorg Med Chem. 2009 May 1;17(9):3266-77. doi: 10.1016/j.bmc.2009.03.052. Epub 2009 Apr 1.

PMID:
19364657
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