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Results: 1 to 20 of 96

1.

Physiologically based pharmacokinetic (PBPK) models for ethanol.

Plawecki MH, Han JJ, Doerschuk PC, Ramchandani VA, O'Connor SJ.

IEEE Trans Biomed Eng. 2008 Dec;55(12):2691-700. doi: 10.1109/TBME.2008.919132.

PMID:
19126448
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology.

Han JJ, Plawecki MH, Doerschuk PC, Ramchandani VA, O'Connor S.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:5033-6.

PMID:
17945874
[PubMed - indexed for MEDLINE]
4.

Intravenous ethanol infusions can mimic the time course of breath alcohol concentrations following oral alcohol administration in healthy volunteers.

Ramchandani VA, Plawecki M, Li TK, O'Connor S.

Alcohol Clin Exp Res. 2009 May;33(5):938-44. doi: 10.1111/j.1530-0277.2009.00906.x. Epub 2009 Mar 11.

PMID:
19320632
[PubMed - indexed for MEDLINE]
5.

A physiologically-based pharmacokinetic (PBPK) model for alcohol facilitates rapid BrAC clamping.

Ramchandani VA, Bolane J, Li TK, O'Connor S.

Alcohol Clin Exp Res. 1999 Apr;23(4):617-23.

PMID:
10235297
[PubMed - indexed for MEDLINE]
6.

Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake.

Laplanche R, Meno-Tetang GM, Kawai R.

J Pharmacokinet Pharmacodyn. 2007 Jun;34(3):373-400. Epub 2007 Mar 13.

PMID:
17431753
[PubMed - indexed for MEDLINE]
7.

Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition.

Poulin P, Theil FP.

J Pharm Sci. 2002 May;91(5):1358-70.

PMID:
11977112
[PubMed - indexed for MEDLINE]
9.

Development and application of a physiologically based pharmacokinetic model for ethanol in the mouse.

Pastino GM, Sultatos LG, Flynn EJ.

Alcohol Alcohol. 1996 Jul;31(4):365-74.

PMID:
8879283
[PubMed - indexed for MEDLINE]
Free Article
10.

Development of multi-route physiologically-based pharmacokinetic models for ethanol in the adult, pregnant, and neonatal rat.

Martin SA, McLanahan ED, El-Masri H, LeFew WR, Bushnell PJ, Boyes WK, Choi K, Clewell HJ 3rd, Campbell JL Jr.

Inhal Toxicol. 2012 Sep;24(11):698-722. doi: 10.3109/08958378.2012.712165.

PMID:
22954395
[PubMed - indexed for MEDLINE]
11.

Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125.

Kawai R, Lemaire M, Steimer JL, Bruelisauer A, Niederberger W, Rowland M.

J Pharmacokinet Biopharm. 1994 Oct;22(5):327-65.

PMID:
7791036
[PubMed - indexed for MEDLINE]
12.

Maintaining steady state arterial alcohol levels in rats by using a physiologically based pharmacokinetic model.

Morzorati SL, Ramchandani VA, Li TK, O'Connor S.

Alcohol. 2002 Nov;28(3):189-95.

PMID:
12551760
[PubMed - indexed for MEDLINE]
13.

Alcohol exposure rate control through physiologically based pharmacokinetic modeling.

Plawecki MH, Zimmermann US, Vitvitskiy V, Doerschuk PC, Crabb D, O'Connor S.

Alcohol Clin Exp Res. 2012 Jun;36(6):1042-9. doi: 10.1111/j.1530-0277.2011.01706.x. Epub 2012 Apr 5.

PMID:
22486174
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Analysis of solvent central nervous system toxicity and ethanol interactions using a human population physiologically based kinetic and dynamic model.

MacDonald AJ, Rostami-Hodjegan A, Tucker GT, Linkens DA.

Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 1):165-76.

PMID:
12052002
[PubMed - indexed for MEDLINE]
15.

A physiologically based pharmacokinetic model for nicotine and cotinine in man.

Robinson DE, Balter NJ, Schwartz SL.

J Pharmacokinet Biopharm. 1992 Dec;20(6):591-609.

PMID:
1302764
[PubMed - indexed for MEDLINE]
16.

Pharmacokinetics and concentration-effect analysis of intravenous RGD891, a platelet GPIIb/IIIa antagonist, using mixed-effects modeling (NONMEM).

Zannikos PN, Rohatagi S, Jensen BK, DePhillips SL, Rhodes GR.

J Clin Pharmacol. 2000 Oct;40(10):1129-40.

PMID:
11028252
[PubMed - indexed for MEDLINE]
17.

Within- and between-subject variations in pharmacokinetic parameters of ethanol by analysis of breath, venous blood and urine.

Norberg A, Gabrielsson J, Jones AW, Hahn RG.

Br J Clin Pharmacol. 2000 May;49(5):399-408.

PMID:
10792196
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Ethanol pharmacokinetics in white women: nonlinear model fitting versus zero-order elimination analyses.

Mumenthaler MS, Taylor JL, Yesavage JA.

Alcohol Clin Exp Res. 2000 Sep;24(9):1353-62.

PMID:
11003200
[PubMed - indexed for MEDLINE]
19.

A distributed parameter physiologically-based pharmacokinetic model for dermal and inhalation exposure to volatile organic compounds.

Roy A, Weisel CP, Lioy PJ, Georgopoulos PG.

Risk Anal. 1996 Apr;16(2):147-60.

PMID:
8638037
[PubMed - indexed for MEDLINE]
20.

Hepatic saturation mechanism of ethanol: application of mathematical models to ethanol outflow profiles in the perfused rat liver.

Matsumoto H, Fukui Y.

Alcohol Clin Exp Res. 1996 Feb;20(1 Suppl):7A-11A.

PMID:
8659696
[PubMed - indexed for MEDLINE]

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