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Items: 1 to 20 of 119

1.

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.

Allen JD, Jaffer ZM, Park SJ, Burgin S, Hofmann C, Sells MA, Chen S, Derr-Yellin E, Michels EG, McDaniel A, Bessler WK, Ingram DA, Atkinson SJ, Travers JB, Chernoff J, Clapp DW.

Blood. 2009 Mar 19;113(12):2695-705. doi: 10.1182/blood-2008-06-160861. Epub 2009 Jan 5.

2.

Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells.

Pivniouk VI, Snapper SB, Kettner A, Alenius H, Laouini D, Falet H, Hartwig J, Alt FW, Geha RS.

Int Immunol. 2003 Dec;15(12):1431-40.

3.

MAPK kinase 3 specifically regulates Fc epsilonRI-mediated IL-4 production by mast cells.

MacNeil AJ, Yang YJ, Lin TJ.

J Immunol. 2011 Sep 15;187(6):3374-82. doi: 10.4049/jimmunol.1003126. Epub 2011 Aug 12.

4.

Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1.

Shumilina E, Lam RS, Wölbing F, Matzner N, Zemtsova IM, Sobiesiak M, Mahmud H, Sausbier U, Biedermann T, Ruth P, Sausbier M, Lang F.

J Immunol. 2008 Jun 15;180(12):8040-7.

5.

Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor alpha chain respond to human IgE in mast cell degranulation and in allergic reactions.

Fung-Leung WP, De Sousa-Hitzler J, Ishaque A, Zhou L, Pang J, Ngo K, Panakos JA, Chourmouzis E, Liu FT, Lau CY.

J Exp Med. 1996 Jan 1;183(1):49-56.

6.

Impaired mast cell maturation and degranulation and attenuated allergic responses in Ndrg1-deficient mice.

Taketomi Y, Sunaga K, Tanaka S, Nakamura M, Arata S, Okuda T, Moon TC, Chang HW, Sugimoto Y, Kokame K, Miyata T, Murakami M, Kudo I.

J Immunol. 2007 Jun 1;178(11):7042-53.

7.

SHIP down-regulates FcepsilonR1-induced degranulation at supraoptimal IgE or antigen levels.

Gimborn K, Lessmann E, Kuppig S, Krystal G, Huber M.

J Immunol. 2005 Jan 1;174(1):507-16.

8.

A TLR2 ligand suppresses allergic inflammatory reactions by acting directly on mast cells.

Kasakura K, Takahashi K, Aizawa T, Hosono A, Kaminogawa S.

Int Arch Allergy Immunol. 2009;150(4):359-69. doi: 10.1159/000226237. Epub 2009 Jul 1.

PMID:
19571568
9.

LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival.

Yamasaki S, Ishikawa E, Sakuma M, Kanagawa O, Cheng AM, Malissen B, Saito T.

Mol Cell Biol. 2007 Jun;27(12):4406-15. Epub 2007 Apr 9.

10.

SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.

Pivniouk VI, Martin TR, Lu-Kuo JM, Katz HR, Oettgen HC, Geha RS.

J Clin Invest. 1999 Jun;103(12):1737-43.

11.

Prolonged culture of mast cells with high-glucose medium enhances the Fc epsilon RI-mediated degranulation response and leukotriene C4 production.

Kitahata Y, Nunomura S, Terui T, Ra C.

Int Arch Allergy Immunol. 2010;152 Suppl 1:22-31. doi: 10.1159/000312122. Epub 2010 Jun 4.

PMID:
20523060
12.

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.

McDaniel AS, Allen JD, Park SJ, Jaffer ZM, Michels EG, Burgin SJ, Chen S, Bessler WK, Hofmann C, Ingram DA, Chernoff J, Clapp DW.

Blood. 2008 Dec 1;112(12):4646-54. doi: 10.1182/blood-2008-04-155085. Epub 2008 Sep 2.

13.

The quantity and duration of FcRgamma signals determine mast cell degranulation and survival.

Yamasaki S, Ishikawa E, Kohno M, Saito T.

Blood. 2004 Apr 15;103(8):3093-101. Epub 2003 Dec 11.

15.
16.

Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells.

Miyata N, Gon Y, Nunomura S, Endo D, Yamashita K, Matsumoto K, Hashimoto S, Ra C.

Int Immunopharmacol. 2008 Jun;8(6):874-80. doi: 10.1016/j.intimp.2008.02.002. Epub 2008 Mar 5.

PMID:
18442792
17.

PI3Kgamma differentially regulates FcepsilonRI-mediated degranulation and migration of mast cells by and toward antigen.

Endo D, Gon Y, Nunomura S, Yamashita K, Hashimoto S, Ra C.

Int Arch Allergy Immunol. 2009;149 Suppl 1:66-72. doi: 10.1159/000211375. Epub 2009 Jun 3.

PMID:
19494508
18.

Fc epsilon RI gamma-ITAM is differentially required for mast cell function in vivo.

Sakurai D, Yamasaki S, Arase K, Park SY, Arase H, Konno A, Saito T.

J Immunol. 2004 Feb 15;172(4):2374-81.

19.

FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.

Nunomura S, Gon Y, Yoshimaru T, Kashiwakura J, Kawakami T, Ra C.

Eur J Immunol. 2010 Apr;40(4):1205-17. doi: 10.1002/eji.200939651.

20.

Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca²⁺ mobilization.

Yuan M, Li J, Lv J, Mo X, Yang C, Chen X, Liu Z, Liu J.

Toxicol Appl Pharmacol. 2012 Nov 1;264(3):462-9. doi: 10.1016/j.taap.2012.08.024. Epub 2012 Aug 30.

PMID:
22959927
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