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Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation.

Cho YY, Tang F, Yao K, Lu C, Zhu F, Zheng D, Pugliese A, Bode AM, Dong Z.

Cancer Res. 2009 Jan 1;69(1):272-81. doi: 10.1158/0008-5472.CAN-08-3125.


P21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformation.

Li T, Zhang J, Zhu F, Wen W, Zykova T, Li X, Liu K, Peng C, Ma W, Shi G, Dong Z, Bode AM, Dong Z.

Carcinogenesis. 2011 May;32(5):659-66. doi: 10.1093/carcin/bgq271. Epub 2010 Dec 22.


Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation.

Zheng D, Cho YY, Lau AT, Zhang J, Ma WY, Bode AM, Dong Z.

Cancer Res. 2008 Sep 15;68(18):7650-60. doi: 10.1158/0008-5472.CAN-08-1137.


Involvement of the paxillin pathway in JB6 Cl41 cell transformation.

Tatsumi Y, Cho YY, He Z, Mizuno H, Seok Choi H, Bode AM, Dong Z.

Cancer Res. 2006 Jun 1;66(11):5968-74.


p38 Mitogen-activated protein kinase regulation of JB6 Cl41 cell transformation promoted by epidermal growth factor.

He Z, Cho YY, Liu G, Ma WY, Bode AM, Dong Z.

J Biol Chem. 2003 Jul 18;278(29):26435-42. Epub 2003 May 13.


Investigation of the cell cycle regulation of cdk3-associated kinase activity and the role of cdk3 in proliferation and transformation.

Braun K, Hölzl G, Soucek T, Geisen C, Möröy T, Hengstschläger M.

Oncogene. 1998 Oct 29;17(17):2259-69.


p73 supports cellular growth through c-Jun-dependent AP-1 transactivation.

Vikhanskaya F, Toh WH, Dulloo I, Wu Q, Boominathan L, Ng HH, Vousden KH, Sabapathy K.

Nat Cell Biol. 2007 Jun;9(6):698-705. Epub 2007 May 13.


Tpl-2 kinase downregulates the activity of p53 and enhances signaling pathways leading to activation of activator protein 1 induced by EGF.

Khanal P, Lee KY, Kang KW, Kang BS, Choi HS.

Carcinogenesis. 2009 Apr;30(4):682-9. doi: 10.1093/carcin/bgp040. Epub 2009 Feb 12.


Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the cheliensisin a inhibition of cell transformation.

Zhu J, Zhang J, Huang H, Li J, Yu Y, Jin H, Li Y, Deng X, Gao J, Zhao Q, Huang C.

Cancer Prev Res (Phila). 2014 Dec;7(12):1270-81. doi: 10.1158/1940-6207.CAPR-14-0233. Epub 2014 Oct 3.


Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation.

Kim HG, Lee KW, Cho YY, Kang NJ, Oh SM, Bode AM, Dong Z.

Cancer Res. 2008 Apr 1;68(7):2538-47. doi: 10.1158/0008-5472.CAN-07-6597.


c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK).

Sevilla A, Santos CR, Barcia R, Vega FM, Lazo PA.

Oncogene. 2004 Nov 25;23(55):8950-8.


The role of glycogen synthase kinase 3beta in the transformation of epidermal cells.

Ma C, Wang J, Gao Y, Gao TW, Chen G, Bower KA, Odetallah M, Ding M, Ke Z, Luo J.

Cancer Res. 2007 Aug 15;67(16):7756-64.


Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity.

Kim G, Khanal P, Lim SC, Yun HJ, Ahn SG, Ki SH, Choi HS.

Carcinogenesis. 2013 Feb;34(2):341-50. doi: 10.1093/carcin/bgs342. Epub 2012 Nov 3.


Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation.

Cho YY, Yao K, Kim HG, Kang BS, Zheng D, Bode AM, Dong Z.

Cancer Res. 2007 Sep 1;67(17):8104-12.


Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.

Davies CC, Chakraborty A, Cipriani F, Haigh K, Haigh JJ, Behrens A.

Nat Cell Biol. 2010 Oct;12(10):963-72. doi: 10.1038/ncb2098. Epub 2010 Sep 19.

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