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Results: 1 to 20 of 316

1.

The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile.

Andersson MK, Enoksson M, Gallwitz M, Hellman L.

Int Immunol. 2009 Jan;21(1):95-104. doi: 10.1093/intimm/dxn128. Epub 2008 Dec 10.

PMID:
19073880
[PubMed - indexed for MEDLINE]
Free Article
2.

The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase.

Andersson MK, Karlson U, Hellman L.

Mol Immunol. 2008 Feb;45(3):766-75. Epub 2007 Aug 6.

PMID:
17681377
[PubMed - indexed for MEDLINE]
3.

Extended substrate specificity of opossum chymase--implications for the origin of mast cell chymases.

Reimer JM, Enoksson M, Samollow PB, Hellman L.

Mol Immunol. 2008 Apr;45(7):2116-25. Epub 2007 Nov 19.

PMID:
18022236
[PubMed - indexed for MEDLINE]
4.

Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity.

Karlson U, Pejler G, Tomasini-Johansson B, Hellman L.

J Biol Chem. 2003 Oct 10;278(41):39625-31. Epub 2003 Aug 4.

PMID:
12900423
[PubMed - indexed for MEDLINE]
Free Article
5.

Extended cleavage specificity of mMCP-1, the major mucosal mast cell protease in mouse-high specificity indicates high substrate selectivity.

Andersson MK, Pemberton AD, Miller HR, Hellman L.

Mol Immunol. 2008 May;45(9):2548-58. doi: 10.1016/j.molimm.2008.01.012. Epub 2008 Mar 3.

PMID:
18313755
[PubMed - indexed for MEDLINE]
6.

The extended substrate recognition profile of the dog mast cell chymase reveals similarities and differences to the human chymase.

Gallwitz M, Enoksson M, Thorpe M, Ge X, Hellman L.

Int Immunol. 2010 Jun;22(6):421-31. doi: 10.1093/intimm/dxq021. Epub 2010 Mar 25.

PMID:
20338912
[PubMed - indexed for MEDLINE]
Free Article
7.

Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2' of substrates.

Andersson MK, Thorpe M, Hellman L.

FEBS J. 2010 May;277(10):2255-67. doi: 10.1111/j.1742-4658.2010.07642.x.

PMID:
20423454
[PubMed - indexed for MEDLINE]
8.

Rat mast cell protease 4 is a beta-chymase with unusually stringent substrate recognition profile.

Karlson U, Pejler G, Froman G, Hellman L.

J Biol Chem. 2002 May 24;277(21):18579-85. Epub 2002 Mar 14.

PMID:
11896050
[PubMed - indexed for MEDLINE]
Free Article
9.

Expression profile of novel members of the rat mast cell protease (rMCP)-2 and (rMCP)-8 families, and functional analyses of mouse mast cell protease (mMCP)-8.

Gallwitz M, Enoksson M, Hellman L.

Immunogenetics. 2007 May;59(5):391-405. Epub 2007 Mar 7.

PMID:
17342483
[PubMed - indexed for MEDLINE]
10.

Extended cleavage specificity of the mast cell chymase from the crab-eating macaque (Macaca fascicularis): an interesting animal model for the analysis of the function of the human mast cell chymase.

Thorpe M, Yu J, Boinapally V, Ahooghalandari P, Kervinen J, Garavilla Ld, Hellman L.

Int Immunol. 2012 Dec;24(12):771-82. doi: 10.1093/intimm/dxs081. Epub 2012 Sep 4.

PMID:
22949566
[PubMed - indexed for MEDLINE]
11.

Albumin is a substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site.

Raymond WW, Ruggles SW, Craik CS, Caughey GH.

J Biol Chem. 2003 Sep 5;278(36):34517-24. Epub 2003 Jun 18.

PMID:
12815038
[PubMed - indexed for MEDLINE]
Free Article
12.

Enzyme histochemical discrimination between tryptase and chymase in mast cells of human gut.

Osman IA, Garrett JR, Smith RE.

J Histochem Cytochem. 1989 Apr;37(4):415-21.

PMID:
2647838
[PubMed - indexed for MEDLINE]
13.

Specificity of the wound-induced leucine aminopeptidase (LAP-A) of tomato activity on dipeptide and tripeptide substrates.

Gu YQ, Walling LL.

Eur J Biochem. 2000 Feb;267(4):1178-87.

PMID:
10672029
[PubMed - indexed for MEDLINE]
Free Article
14.

Substrate specificity of porcine renin: P1', P1, and P3 residues of renin substrates are crucial for activity.

Wang W, Liang TC.

Biochemistry. 1994 Dec 6;33(48):14636-41.

PMID:
7981226
[PubMed - indexed for MEDLINE]
15.

The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity.

Pereira PJ, Wang ZM, Rubin H, Huber R, Bode W, Schechter NM, Strobl S.

J Mol Biol. 1999 Feb 12;286(1):163-73.

PMID:
9931257
[PubMed - indexed for MEDLINE]
16.

Structural basis for elastolytic substrate specificity in rodent alpha-chymases.

Kervinen J, Abad M, Crysler C, Kolpak M, Mahan AD, Masucci JA, Bayoumy S, Cummings MD, Yao X, Olson M, de Garavilla L, Kuo L, Deckman I, Spurlino J.

J Biol Chem. 2008 Jan 4;283(1):427-36. Epub 2007 Oct 31.

PMID:
17981788
[PubMed - indexed for MEDLINE]
Free Article
17.

Guinea pig chymase is leucine-specific: a novel example of functional plasticity in the chymase/granzyme family of serine peptidases.

Caughey GH, Beauchamp J, Schlatter D, Raymond WW, Trivedi NN, Banner D, Mauser H, Fingerle J.

J Biol Chem. 2008 May 16;283(20):13943-51. doi: 10.1074/jbc.M710502200. Epub 2008 Mar 19.

PMID:
18353771
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mast cell alpha-chymase reduces IgE recognition of birch pollen profilin by cleaving antibody-binding epitopes.

Mellon MB, Frank BT, Fang KC.

J Immunol. 2002 Jan 1;168(1):290-7.

PMID:
11751973
[PubMed - indexed for MEDLINE]
Free Article
19.

Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart.

Kinoshita A, Urata H, Bumpus FM, Husain A.

J Biol Chem. 1991 Oct 15;266(29):19192-7.

PMID:
1918036
[PubMed - indexed for MEDLINE]
Free Article
20.

Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease.

Stöcker W, Ng M, Auld DS.

Biochemistry. 1990 Nov 13;29(45):10418-25.

PMID:
2261483
[PubMed - indexed for MEDLINE]

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