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19064279,19506359,19506352,17164493,19584715,19506361,16276467,17549293,11992235,16977574,10544913,19506353,18055988,19506358,16247740,18766263,20460340,18031294,16959681,11916080,19786936,19506363,16420565,11992238,18312368,18175279,20806123,16024332,9881332,17000885,21193108,19506362,19506360,11992242,19404524,23289190,15086321,18284449,16977573,16977567,11994985,17701477,11858481,18078393,11019962,22102203,11992241,3142084,11992239,18678140,16862524,18175280,22487084,15304044,25300811,17721617,26743192,24758424,9198217,11841416,15166918,10456451,8874865,16862525,22102205,22102198,17596142,24028703,16454628,29742318,21824283,16862518,10741895,16359507,21885953,22102197,18173689,9608359,19308894,11057847,8296790,20724302,21057713,23551532,11260057,12932308,18786009,9684782,24891215,28980759,11341497,20589313,26411913,18312366,17786534,15984956,17439628,25545301,10063997,24750681,2115785,7890268,16634745,16684011,32107842,7992599,1901629,18510569,18208537,18282712,15086320,3111674,18498402,11260278,21264446,9364997,10215955,17408405,17634944,22268616,21437358,22102194,10669166,16194199,31085919,11992243,22102186,26206100,20331755,16607078,12551832,29168270,16887898,10929043,15198739,15260819,22102202,21178586,35192687,30735311,22450546,21186048,21148813,21371195,19506357,33215808,11686107,16788311,16977571,10063996,25077350,29727738,15938072,14981837,22102193,8339998,11992237,18445014,19286880,18449422,8822593,16862521,3122318,21094983,2096485,32159272,1768767,16634747,16977566,16823821,28804843,24319188,19506355,9864923,24796601,25425019,16959682,18380871,20886181,23730809,21725579,17155947,22057258,11132651,10335531,27443694,11380626,23321055,18393148,12395174,14608197,8075304,11843298,12801845,3116703,18637846,15630508,21951857,27076201,23205618,11057863,18230755,11154147,12911582,28120508,1550779,11026108,18315614,10739386,21643680,7833254,17490729,8903002,16862526,19298374,21535320,20301765,15981443,23238591,20008189,23014972,16862519,15937368,17403090,8199023,19563498,15213847,25756206,11150026,21322782,18510523,12826528,18521502,21571959,8790543,11563592,15311161,24750680,20713487,16131435,23452742,12817437,30358069,16684010,29767844,21429375,8560432,27622788,18786010,16519045,23290978,16149022,6965697,12162689,16704443,15041272,22221847,22102204,26172561,16470522,27472426,23051555,8854570,12032528,11756169,17490730,10468873,14607757,14630825,7893933,11686101,25333737,22102187,19630772,19506364,15479393,34986515,8456431,2465960,18923835,18691167,10495907,28082469,30305529,9692396,30397685,19944257,8148475,22102200,18624696,17286766,17606445,6424339,17883169,21515067,17922807,24351655,1703813,18680527,9423220,11992244,8607125,12199669,25103956,29098718,28804846,24978322,21949039,19086374,11279640,16862523,27913545,9369071,32135566,22918553,24913998,12817908,24065240,32746466,15461624,16416741,16953269,20613494,8191394,21509710,25605439,3257148,2508742,21689209,15849522,18278174,7819109,19110525,18976254,25930155,6609219,25595881,19506356,24762278,19503633,27426859,16977572,14521604,21042662,22102206,23570742,10226348,18078394,16276466,10494764,3266380,21070498,16395486,15103936,10650863,11601234,32864555,25192242,21118340,22740102,10932002,10078119,16176858,8457648,18055987,14754609,3126081,8494994,28804845,35803263,2591151,15238142,27427955,15679619,30378120,23496210,11686104,8456322,9046981,12649145,9268197,14750934,27978590,24581275,15662613,9811523,18315556,19422453,29064615,16420575,25102895,3087003,8367196,10959689,31808831,22102190,18397285,24118466,26791163,19132162,27648611,22004444,6813999,16999850,22389132,31466808,12083507,20210927,24750783,12924038,19149848,25480632,23006049,2106689,16444436,31834934,30866149,30084138,21668503,34511999,20179578,22102199,28765701,19763352,24251732,22102201,23919249,8191164,12199668,17579568,3502198,16634746,36598376,18556568,11292185,18175283,2266049,29378356,23401903,29913537,20727070,28586149,22507643,35521728,14652648,27481874,9253800,27029718,28804847,20739614,11938574,2366336,29427305,14526622,1949703,18344424,9350193,36381287,11880730,23042386,22127528,12353064,15491964,17059421,10669163,19694940,17635702,18755868,1419807,2786279,15650550,3499101,17949477,16676067,19394040,28804848,8579058,24351199,18989523,18786008,26843468,23340442,29369083,1606286,7545380,6420925,34758185,7578526,8426951,35772170,31496264,16862522,35505650,12640572,10959711,27214360,1566742,31229334,35446929,19474451,23439003,32419248,2125251,26207643,16246252,34130347,27622750,11343385,26838696,16320153,16862528,3876122,22237978,25673639,10456467,3087159,11426494,16862520,16889557,16276468,16580053,17375300,1607320,32629500,2105540,16835381,11240613,3879020,3925573,35322397,17439831,32998182,17973844,16359504,9442254,18173693,11920189,19630771,24281894,29115006,8167176,9424737,35168962,33555083,2495715,1412160,17205535,19719828,16616322,27913547,27237807,15086319,34556362,30046743,7667843,29924855,36807283,9759633,6781527,11878805,27065574,35210927,27061057,28804844,31808884,1650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Desmopressin therapy to assist the functional identification and characterisation of von Willebrand disease: differential utility from combining two (VWF:CB and VWF:RCo) von Willebrand factor activity assays?

Favaloro EJ, Thom J, Patterson D, Just S, Dixon T, Koutts J, Baccala M, Rowell J, Baker R. Favaloro EJ, et al. Thromb Res. 2009 Apr;123(6):862-8. doi: 10.1016/j.thromres.2008.10.008. Epub 2008 Dec 7. Thromb Res. 2009. PMID: 19064279

Laboratory diagnosis of von Willebrand disease type 1/2E (2A subtype IIE), type 1 Vicenza and mild type 1 caused by mutations in the D3, D4, B1-B3 and C1-C2 domains of the von Willebrand factor gene. Role of von Willebrand factor multimers and the von Willebrand factor propeptide/antigen ratio.

Gadisseur A, Berneman Z, Schroyens W, Michiels JJ. Gadisseur A, et al. Acta Haematol. 2009;121(2-3):128-38. doi: 10.1159/000214853. Epub 2009 Jun 8. Acta Haematol. 2009. PMID: 19506359 Review.

Laboratory diagnosis and molecular classification of von Willebrand disease.

Gadisseur A, Hermans C, Berneman Z, Schroyens W, Deckmyn H, Michiels JJ. Gadisseur A, et al. Acta Haematol. 2009;121(2-3):71-84. doi: 10.1159/000214846. Epub 2009 Jun 8. Acta Haematol. 2009. PMID: 19506352 Review.

Intravenous DDAVP and factor VIII-von Willebrand factor concentrate for the treatment and prophylaxis of bleedings in patients With von Willebrand disease type 1, 2 and 3.

Michiels JJ, van Vliet HH, Berneman Z, Gadisseur A, van der Planken M, Schroyens W, van der Velden A, Budde U. Michiels JJ, et al. Clin Appl Thromb Hemost. 2007 Jan;13(1):14-34. doi: 10.1177/1076029606296399. Clin Appl Thromb Hemost. 2007. PMID: 17164493 Free article. Review.

Potential supplementary utility of combined PFA-100 and functional von Willebrand factor testing for the laboratory assessment of desmopressin and factor concentrate therapy in von Willebrand disease.

Favaloro EJ, Thom J, Patterson D, Just S, Baccala M, Dixon T, Meiring M, Koutts J, Rowell J, Baker R. Favaloro EJ, et al. Blood Coagul Fibrinolysis. 2009 Sep;20(6):475-83. doi: 10.1097/MBC.0b013e32832da1ad. Blood Coagul Fibrinolysis. 2009. PMID: 19584715

Dominant von Willebrand disease type 2M and 2U are variable expressions of one distinct disease entity caused by loss-of-function mutations in the A1 domain of the von Willebrand factor gene.

Gadisseur A, van der Planken M, Schroyens W, Berneman Z, Michiels JJ. Gadisseur A, et al. Acta Haematol. 2009;121(2-3):145-53. doi: 10.1159/000214855. Epub 2009 Jun 8. Acta Haematol. 2009. PMID: 19506361 Review.

Characterization, classification, and treatment of von Willebrand diseases: a critical appraisal of the literature and personal experiences.

Michiels JJ, Gadisseur A, Budde U, Berneman Z, van der Planken M, Schroyens W, van de Velde A, van Vliet H. Michiels JJ, et al. Semin Thromb Hemost. 2005 Nov;31(5):577-601. doi: 10.1055/s-2005-922230. Semin Thromb Hemost. 2005. PMID: 16276467 Review.

Comparison of the pharmacokinetics of two von Willebrand factor concentrates [Biostate and AHF (High Purity)] in people with von Willebrand disorder. A randomised cross-over, multi-centre study.

Favaloro EJ, Lloyd J, Rowell J, Baker R, Rickard K, Kershaw G, Street A, Scarff K, Barrese G, Maher D, McLachlan AJ. Favaloro EJ, et al. Thromb Haemost. 2007 Jun;97(6):922-30. Thromb Haemost. 2007. PMID: 17549293 Clinical Trial.

Response of von Willebrand factor parameters to desmopressin in patients with type 1 and type 2 congenital von Willebrand disease: diagnostic and therapeutic implications.

Michiels JJ, van de Velde A, van Vliet HH, van der Planken M, Schroyens W, Berneman Z. Michiels JJ, et al. Semin Thromb Hemost. 2002 Apr;28(2):111-32. doi: 10.1055/s-2002-27814. Semin Thromb Hemost. 2002. PMID: 11992235 Clinical Trial.

Guidelines for the evaluation of intravenous desmopressin and von Willebrand factor/factor VIII concentrate in the treatment and prophylaxis of bleedings in von Willebrand disease types 1, 2, and 3.

Michiels JJ, Gadisseur A, van der Planken M, Schroyens W, van de Velden A, Berneman Z. Michiels JJ, et al. Semin Thromb Hemost. 2006 Sep;32(6):636-45. doi: 10.1055/s-2006-949669. Semin Thromb Hemost. 2006. PMID: 16977574 Review.

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