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Results: 1 to 20 of 101

1.

Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury.

Regner KR, Zuk A, Van Why SK, Shames BD, Ryan RP, Falck JR, Manthati VL, McMullen ME, Ledbetter SR, Roman RJ.

Kidney Int. 2009 Mar;75(5):511-7. doi: 10.1038/ki.2008.600. Epub 2008 Dec 3.

PMID:
19052533
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Manthati VL, Falck JR, Malik KU.

Nitric Oxide. 2013 Sep 1;33:18-41. doi: 10.1016/j.niox.2013.05.001. Epub 2013 May 14.

PMID:
23684565
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury.

Hoff U, Lukitsch I, Chaykovska L, Ladwig M, Arnold C, Manthati VL, Fuller TF, Schneider W, Gollasch M, Muller DN, Flemming B, Seeliger E, Luft FC, Falck JR, Dragun D, Schunck WH.

Kidney Int. 2011 Jan;79(1):57-65. doi: 10.1038/ki.2010.377. Epub 2010 Oct 20.

PMID:
20962739
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.

Renic M, Kumar SN, Gebremedhin D, Florence MA, Gerges NZ, Falck JR, Harder DR, Roman RJ.

Am J Physiol Heart Circ Physiol. 2012 Mar 15;302(6):H1285-93. doi: 10.1152/ajpheart.00340.2011. Epub 2012 Jan 13.

PMID:
22245774
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The protective effect of HET0016 on brain edema and blood-brain barrier dysfunction after cerebral ischemia/reperfusion.

Liu Y, Wang D, Wang H, Qu Y, Xiao X, Zhu Y.

Brain Res. 2014 Jan 28;1544:45-53. doi: 10.1016/j.brainres.2013.11.031. Epub 2013 Dec 6.

PMID:
24316243
[PubMed - indexed for MEDLINE]
6.

A synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in rats.

Cuez T, Korkmaz B, Buharalioglu CK, Sahan-Firat S, Falck J, Malik KU, Tunctan B.

Basic Clin Pharmacol Toxicol. 2010 May;106(5):378-88. doi: 10.1111/j.1742-7843.2009.00501.x. Epub 2009 Dec 7.

PMID:
20002062
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Recovery from renal ischemia-reperfusion injury is associated with altered renal hemodynamics, blunted pressure natriuresis, and sodium-sensitive hypertension.

Pechman KR, De Miguel C, Lund H, Leonard EC, Basile DP, Mattson DL.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1358-63. doi: 10.1152/ajpregu.91022.2008. Epub 2009 Aug 26.

PMID:
19710386
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia.

Poloyac SM, Zhang Y, Bies RR, Kochanek PM, Graham SH.

J Cereb Blood Flow Metab. 2006 Dec;26(12):1551-61. Epub 2006 Mar 29.

PMID:
16570075
[PubMed - indexed for MEDLINE]
9.

A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats.

Tunctan B, Korkmaz B, Buharalioglu CK, Firat SS, Anjaiah S, Falck J, Roman RJ, Malik KU.

Shock. 2008 Sep;30(3):329-35. doi: 10.1097/SHK.0b013e31816471c6.

PMID:
18323740
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

20-HETE contributes to the acute fall in cerebral blood flow after subarachnoid hemorrhage in the rat.

Kehl F, Cambj-Sapunar L, Maier KG, Miyata N, Kametani S, Okamoto H, Hudetz AG, Schulte ML, Zagorac D, Harder DR, Roman RJ.

Am J Physiol Heart Circ Physiol. 2002 Apr;282(4):H1556-65.

PMID:
11893593
[PubMed - indexed for MEDLINE]
Free Article
11.

20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.

Ding Y, Wu CC, Garcia V, Dimitrova I, Weidenhammer A, Joseph G, Zhang F, Manthati VL, Falck JR, Capdevila JH, Schwartzman ML.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F753-63. doi: 10.1152/ajprenal.00292.2013. Epub 2013 Jul 3.

PMID:
23825080
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Differential effects of 20-hydroxyeicosatetraenoic acid on intrarenal blood flow in the rat.

Oyekan AO.

J Pharmacol Exp Ther. 2005 Jun;313(3):1289-95. Epub 2005 Mar 15.

PMID:
15769866
[PubMed - indexed for MEDLINE]
Free Article
13.

Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine.

Fernandez MM, Gonzalez D, Williams JM, Roman RJ, Nowicki S.

Eur J Pharmacol. 2012 Jul 5;686(1-3):97-103. doi: 10.1016/j.ejphar.2012.04.039. Epub 2012 May 2.

PMID:
22575524
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Effects of a 20-HETE antagonist and agonists on cerebral vascular tone.

Yu M, Cambj-Sapunar L, Kehl F, Maier KG, Takeuchi K, Miyata N, Ishimoto T, Reddy LM, Falck JR, Gebremedhin D, Harder DR, Roman RJ.

Eur J Pharmacol. 2004 Feb 23;486(3):297-306.

PMID:
14985052
[PubMed - indexed for MEDLINE]
15.

5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKβ/IκB-α/NF-κB pathway, and proinflammatory cytokine formation.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Falck JR, Malik KU.

Prostaglandins Other Lipid Mediat. 2013 Apr-May;102-103:31-41. doi: 10.1016/j.prostaglandins.2013.01.005. Epub 2013 Feb 27.

PMID:
23454652
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo.

Yin M, Zhong Z, Connor HD, Bunzendahl H, Finn WF, Rusyn I, Li X, Raleigh JA, Mason RP, Thurman RG.

Am J Physiol Renal Physiol. 2002 Mar;282(3):F417-23.

PMID:
11832421
[PubMed - indexed for MEDLINE]
Free Article
17.

20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F.

Am J Physiol Renal Physiol. 2009 Sep;297(3):F662-70. doi: 10.1152/ajprenal.00146.2009. Epub 2009 Jul 1.

PMID:
19570883
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Role of endogenous CYP450 metabolites of arachidonic acid in maintaining the glomerular protein permeability barrier.

Williams JM, Sharma M, Anjaiahh S, Falck JR, Roman RJ.

Am J Physiol Renal Physiol. 2007 Aug;293(2):F501-5. Epub 2007 May 16.

PMID:
17507602
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Protection by 20-5,14-HEDGE against surgically induced ischemia reperfusion lung injury in rats.

Ali I, Gruenloh S, Gao Y, Clough A, Falck JR, Medhora M, Jacobs ER.

Ann Thorac Surg. 2012 Jan;93(1):282-8. doi: 10.1016/j.athoracsur.2011.08.074. Epub 2011 Nov 23.

PMID:
22115333
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Role of 20-hydroxyeicosatetraenoic acid in mediating hypertension in response to chronic renal medullary endothelin type B receptor blockade.

Speed JS, George EM, Arany M, Cockrell K, Granger JP.

PLoS One. 2011;6(10):e26063. doi: 10.1371/journal.pone.0026063. Epub 2011 Oct 7.

PMID:
22016812
[PubMed - indexed for MEDLINE]
Free PMC Article

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