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Results: 1 to 20 of 122

1.

Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane.

Schmidt D, MacKinnon R.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19276-81. doi: 10.1073/pnas.0810187105. Epub 2008 Dec 2.

PMID:
19050073
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers.

Schmidt D, Cross SR, MacKinnon R.

J Mol Biol. 2009 Jul 31;390(5):902-12. doi: 10.1016/j.jmb.2009.05.062. Epub 2009 May 27.

PMID:
19481093
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom.

Lee SY, MacKinnon R.

Nature. 2004 Jul 8;430(6996):232-5.

PMID:
15241419
[PubMed - indexed for MEDLINE]
4.

Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II.

Sokolov S, Kraus RL, Scheuer T, Catterall WA.

Mol Pharmacol. 2008 Mar;73(3):1020-8. Epub 2007 Dec 21.

PMID:
18156314
[PubMed - indexed for MEDLINE]
Free Article
5.

Interaction between extracellular Hanatoxin and the resting conformation of the voltage-sensor paddle in Kv channels.

Lee HC, Wang JM, Swartz KJ.

Neuron. 2003 Oct 30;40(3):527-36.

PMID:
14642277
[PubMed - indexed for MEDLINE]
6.

Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels.

Lee SY, Banerjee A, MacKinnon R.

PLoS Biol. 2009 Mar 3;7(3):e47. doi: 10.1371/journal.pbio.1000047.

PMID:
19260762
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The interaction of spider gating modifier peptides with voltage-gated potassium channels.

Huang PT, Shiau YS, Lou KL.

Toxicon. 2007 Feb;49(2):285-92. Epub 2006 Sep 27. Review.

PMID:
17113615
[PubMed - indexed for MEDLINE]
8.

Vstx1, a modifier of Kv channel gating, localizes to the interfacial region of lipid bilayers.

Bemporad D, Sands ZA, Wee CL, Grottesi A, Sansom MS.

Biochemistry. 2006 Oct 3;45(39):11844-55.

PMID:
17002285
[PubMed - indexed for MEDLINE]
9.

Ion channels: gate expectations.

Garcia ML.

Nature. 2004 Jul 8;430(6996):153-5. No abstract available.

PMID:
15241399
[PubMed - indexed for MEDLINE]
10.

Functional analysis of Kv1.2 and paddle chimera Kv channels in planar lipid bilayers.

Tao X, MacKinnon R.

J Mol Biol. 2008 Sep 26;382(1):24-33. doi: 10.1016/j.jmb.2008.06.085. Epub 2008 Jul 7.

PMID:
18638484
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels.

Tao H, Chen JJ, Xiao YC, Wu YY, Su HB, Li D, Wang HY, Deng MC, Wang MC, Liu ZH, Liang SP.

Biochemistry. 2013 Oct 22;52(42):7439-48. doi: 10.1021/bi4006418. Epub 2013 Oct 7.

PMID:
24044413
[PubMed - indexed for MEDLINE]
12.

Localization of the voltage-sensor toxin receptor on KvAP.

Ruta V, MacKinnon R.

Biochemistry. 2004 Aug 10;43(31):10071-9.

PMID:
15287735
[PubMed - indexed for MEDLINE]
13.

Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel.

Jung HJ, Lee JY, Kim SH, Eu YJ, Shin SY, Milescu M, Swartz KJ, Kim JI.

Biochemistry. 2005 Apr 26;44(16):6015-23.

PMID:
15835890
[PubMed - indexed for MEDLINE]
14.

Opening the shaker K+ channel with hanatoxin.

Milescu M, Lee HC, Bae CH, Kim JI, Swartz KJ.

J Gen Physiol. 2013 Feb;141(2):203-16. doi: 10.1085/jgp.201210914.

PMID:
23359283
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins.

Takahashi H, Kim JI, Min HJ, Sato K, Swartz KJ, Shimada I.

J Mol Biol. 2000 Mar 31;297(3):771-80.

PMID:
10731427
[PubMed - indexed for MEDLINE]
16.

Portability of paddle motif function and pharmacology in voltage sensors.

Alabi AA, Bahamonde MI, Jung HJ, Kim JI, Swartz KJ.

Nature. 2007 Nov 15;450(7168):370-5.

PMID:
18004375
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Role of charged residues in the S1-S4 voltage sensor of BK channels.

Ma Z, Lou XJ, Horrigan FT.

J Gen Physiol. 2006 Mar;127(3):309-28.

PMID:
16505150
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

JZTX-XIII, a Kv channel gating modifier toxin from Chinese tarantula Chilobrachys jingzhao.

Yuan C, Liu Z, Hu W, Gao T, Liang S.

Toxicon. 2012 Feb;59(2):265-71. doi: 10.1016/j.toxicon.2011.11.021. Epub 2011 Dec 8.

PMID:
22155305
[PubMed - indexed for MEDLINE]
19.

Structural compatibility between the putative voltage sensor of voltage-gated K+ channels and the prokaryotic KcsA channel.

Caprini M, Ferroni S, Planells-Cases R, Rueda J, Rapisarda C, Ferrer-Montiel A, Montal M.

J Biol Chem. 2001 Jun 15;276(24):21070-6. Epub 2001 Mar 26.

PMID:
11274182
[PubMed - indexed for MEDLINE]
Free Article
20.

Voltage-sensor activation with a tarantula toxin as cargo.

Phillips LR, Milescu M, Li-Smerin Y, Mindell JA, Kim JI, Swartz KJ.

Nature. 2005 Aug 11;436(7052):857-60.

PMID:
16094370
[PubMed - indexed for MEDLINE]

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