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Results: 1 to 20 of 164

1.

Metabotropic glutamate receptor-mediated use-dependent down-regulation of synaptic excitability involves the fragile X mental retardation protein.

Repicky S, Broadie K.

J Neurophysiol. 2009 Feb;101(2):672-87. doi: 10.1152/jn.90953.2008. Epub 2008 Nov 26.

PMID:
19036865
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mechanistic relationships between Drosophila fragile X mental retardation protein and metabotropic glutamate receptor A signaling.

Pan L, Woodruff E 3rd, Liang P, Broadie K.

Mol Cell Neurosci. 2008 Apr;37(4):747-60. doi: 10.1016/j.mcn.2008.01.003. Epub 2008 Jan 17.

PMID:
18280750
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology.

Bogdanik L, Mohrmann R, Ramaekers A, Bockaert J, Grau Y, Broadie K, Parmentier ML.

J Neurosci. 2004 Oct 13;24(41):9105-16.

PMID:
15483129
[PubMed - indexed for MEDLINE]
Free Article
5.

Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase.

Siller SS, Broadie K.

Dis Model Mech. 2011 Sep;4(5):673-85. doi: 10.1242/dmm.008045. Epub 2011 Jun 13.

PMID:
21669931
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure.

Gatto CL, Broadie K.

Development. 2008 Aug;135(15):2637-48. doi: 10.1242/dev.022244. Epub 2008 Jun 25.

PMID:
18579676
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Learning and memory deficits consequent to reduction of the fragile X mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila.

Kanellopoulos AK, Semelidou O, Kotini AG, Anezaki M, Skoulakis EM.

J Neurosci. 2012 Sep 19;32(38):13111-24.

PMID:
22993428
[PubMed - indexed for MEDLINE]
Free Article
8.

Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.

Coffee RL Jr, Tessier CR, Woodruff EA 3rd, Broadie K.

Dis Model Mech. 2010 Jul-Aug;3(7-8):471-85. doi: 10.1242/dmm.004598. Epub 2010 May 4.

PMID:
20442204
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.

Coffee RL Jr, Williamson AJ, Adkins CM, Gray MC, Page TL, Broadie K.

Hum Mol Genet. 2012 Feb 15;21(4):900-15. doi: 10.1093/hmg/ddr527. Epub 2011 Nov 11.

PMID:
22080836
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis.

Auerbach BD, Bear MF.

J Neurophysiol. 2010 Aug;104(2):1047-51. doi: 10.1152/jn.00449.2010. Epub 2010 Jun 16.

PMID:
20554840
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.

Niere F, Wilkerson JR, Huber KM.

J Neurosci. 2012 Apr 25;32(17):5924-36. doi: 10.1523/JNEUROSCI.4650-11.2012.

PMID:
22539853
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models.

Zhang J, Hou L, Klann E, Nelson DL.

J Neurophysiol. 2009 May;101(5):2572-80. doi: 10.1152/jn.90558.2008. Epub 2009 Feb 25.

PMID:
19244359
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.

Bhogal B, Jepson JE, Savva YA, Pepper AS, Reenan RA, Jongens TA.

Nat Neurosci. 2011 Oct 30;14(12):1517-24. doi: 10.1038/nn.2950.

PMID:
22037499
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.

Ronesi JA, Huber KM.

Sci Signal. 2008 Feb 5;1(5):pe6. doi: 10.1126/stke.15pe6. Review.

PMID:
18272470
[PubMed - indexed for MEDLINE]
15.

Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila.

Friedman SH, Dani N, Rushton E, Broadie K.

Dis Model Mech. 2013 Nov;6(6):1400-13. doi: 10.1242/dmm.012229. Epub 2013 Sep 5.

PMID:
24046358
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Presynaptic impairment of synaptic transmission in Drosophila embryos lacking Gs(alpha).

Hou D, Suzuki K, Wolfgang WJ, Clay C, Forte M, Kidokoro Y.

J Neurosci. 2003 Jul 2;23(13):5897-905.

PMID:
12843294
[PubMed - indexed for MEDLINE]
Free Article
17.

c-Jun N-terminal kinase regulates mGluR-dependent expression of post-synaptic FMRP target proteins.

Schmit TL, Dowell JA, Maes ME, Wilhelm M.

J Neurochem. 2013 Dec;127(6):772-81. doi: 10.1111/jnc.12453. Epub 2013 Oct 24.

PMID:
24047560
[PubMed - indexed for MEDLINE]
Free Article
18.

Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse.

Higashimori H, Morel L, Huth J, Lindemann L, Dulla C, Taylor A, Freeman M, Yang Y.

Hum Mol Genet. 2013 May 15;22(10):2041-54. doi: 10.1093/hmg/ddt055. Epub 2013 Feb 7.

PMID:
23396537
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model.

Gatto CL, Pereira D, Broadie K.

Neurobiol Dis. 2014 May;65:142-59. doi: 10.1016/j.nbd.2014.01.008. Epub 2014 Jan 12.

PMID:
24423648
[PubMed - indexed for MEDLINE]
20.

The metabotropic glutamate receptor activates the lipid kinase PI3K in Drosophila motor neurons through the calcium/calmodulin-dependent protein kinase II and the nonreceptor tyrosine protein kinase DFak.

Chun-Jen Lin C, Summerville JB, Howlett E, Stern M.

Genetics. 2011 Jul;188(3):601-13. doi: 10.1534/genetics.111.128561. Epub 2011 Apr 21.

PMID:
21515581
[PubMed - indexed for MEDLINE]
Free PMC Article

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