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Results: 1 to 20 of 151

1.

Rubidium efflux as a tool for the pharmacological characterisation of compounds with BK channel opening properties.

McKay NG, Kirby RW, Lawson K.

Methods Mol Biol. 2008;491:267-77. doi: 10.1007/978-1-59745-526-8_21.

PMID:
18998100
[PubMed - indexed for MEDLINE]
2.

Functional analysis of large conductance Ca2(+)-activated K(+) channels: ion flux studies by atomic absorption spectrometry.

Parihar AS, Groebe DR, Scott VE, Feng J, Zhang XF, Warrior U, Gopalakrishnan M, Shieh CC.

Assay Drug Dev Technol. 2003 Oct;1(5):647-54.

PMID:
15090237
[PubMed - indexed for MEDLINE]
3.

Validation of an atomic absorption rubidium ion efflux assay for KCNQ/M-channels using the ion Channel Reader 8000.

Wang K, McIlvain B, Tseng E, Kowal D, Jow F, Shen R, Zhang H, Shan QJ, He L, Chen D, Lu Q, Dunlop J.

Assay Drug Dev Technol. 2004 Oct;2(5):525-34.

PMID:
15671650
[PubMed - indexed for MEDLINE]
4.

Evaluation of the rubidium efflux assay for preclinical identification of HERG blockade.

Chaudhary KW, O'Neal JM, Mo ZL, Fermini B, Gallavan RH, Bahinski A.

Assay Drug Dev Technol. 2006 Feb;4(1):73-82.

PMID:
16506891
[PubMed - indexed for MEDLINE]
5.

Functional analysis of native and recombinant ion channels using a high-capacity nonradioactive rubidium efflux assay.

Terstappen GC.

Anal Biochem. 1999 Aug 1;272(2):149-55.

PMID:
10415083
[PubMed - indexed for MEDLINE]
6.

Hypoxia increases BK channel activity in the inner mitochondrial membrane.

Gu XQ, Siemen D, Parvez S, Cheng Y, Xue J, Zhou D, Sun X, Jonas EA, Haddad GG.

Biochem Biophys Res Commun. 2007 Jun 22;358(1):311-6. Epub 2007 Apr 25.

PMID:
17481584
[PubMed - indexed for MEDLINE]
7.

Apparent intermediate K conductance channel hyposmotic activation in human lens epithelial cells.

Lauf PK, Misri S, Chimote AA, Adragna NC.

Am J Physiol Cell Physiol. 2008 Mar;294(3):C820-32. doi: 10.1152/ajpcell.00375.2007. Epub 2008 Jan 9.

PMID:
18184876
[PubMed - indexed for MEDLINE]
Free Article
8.

BK channel openers inhibit ROS production of isolated rat brain mitochondria.

Kulawiak B, Kudin AP, Szewczyk A, Kunz WS.

Exp Neurol. 2008 Aug;212(2):543-7. doi: 10.1016/j.expneurol.2008.05.004. Epub 2008 May 20.

PMID:
18572168
[PubMed - indexed for MEDLINE]
9.

Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells.

Wimmers S, Halsband C, Seyler S, Milenkovic V, Strauss O.

Mol Vis. 2008;14:2340-8. Epub 2008 Dec 15.

PMID:
19096717
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A medium-throughput functional assay of KCNQ2 potassium channels using rubidium efflux and atomic absorption spectrometry.

Scott CW, Wilkins DE, Trivedi S, Crankshaw DJ.

Anal Biochem. 2003 Aug 15;319(2):251-7.

PMID:
12871719
[PubMed - indexed for MEDLINE]
11.

Large conductance Ca(2+)-activated K(+) channel (BKCa) activating properties of a series of novel N-arylbenzamides: Channel subunit dependent effects.

Kirby RW, Martelli A, Calderone V, McKay NG, Lawson K.

Bioorg Med Chem. 2013 Jul 15;21(14):4186-91. doi: 10.1016/j.bmc.2013.05.003. Epub 2013 May 14.

PMID:
23707646
[PubMed - indexed for MEDLINE]
12.

Asymmetry of Rb+ conduction emerged under bi-ionic conditions in epithelial maxi-K+ channels.

Ohsaga A, Murata Y, Kondo Y, Hira R, Maruyama Y.

J Physiol Sci. 2008 Dec;58(6):363-9. doi: 10.2170/physiolsci.RP007508.

PMID:
18842165
[PubMed - indexed for MEDLINE]
13.

The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells.

Han X, Xi L, Wang H, Huang X, Ma X, Han Z, Wu P, Ma X, Lu Y, Wang G, Zhou J, Ma D.

Biochem Biophys Res Commun. 2008 Oct 17;375(2):205-9. doi: 10.1016/j.bbrc.2008.07.161. Epub 2008 Aug 13.

PMID:
18706395
[PubMed - indexed for MEDLINE]
14.

Inhibition of martentoxin on neuronal BK channel subtype (alpha+beta4): implications for a novel interaction model.

Shi J, He HQ, Zhao R, Duan YH, Chen J, Chen Y, Yang J, Zhang JW, Shu XQ, Zheng P, Ji YH.

Biophys J. 2008 May 1;94(9):3706-13. doi: 10.1529/biophysj.107.122150. Epub 2008 Jan 16.

PMID:
18199674
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Human monocytes kill M-CSF-expressing glioma cells by BK channel activation.

Hoa NT, Zhang JG, Delgado CL, Myers MP, Callahan LL, Vandeusen G, Schiltz PM, Wepsic HT, Jadus MR.

Lab Invest. 2007 Feb;87(2):115-29.

PMID:
17318194
[PubMed - indexed for MEDLINE]
Free Article
16.

Application of cryopreserved cells to HERG screening using a non-radioactive Rb+ efflux assay.

Ding M, Stjernborg L, Albertson N.

Assay Drug Dev Technol. 2006 Feb;4(1):83-8.

PMID:
16506892
[PubMed - indexed for MEDLINE]
17.

A novel potassium channel in skeletal muscle mitochondria.

Skalska J, Piwońska M, Wyroba E, Surmacz L, Wieczorek R, Koszela-Piotrowska I, Zielińska J, Bednarczyk P, Dołowy K, Wilczynski GM, Szewczyk A, Kunz WS.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):651-9. doi: 10.1016/j.bbabio.2008.05.007. Epub 2008 May 20.

PMID:
18515063
[PubMed - indexed for MEDLINE]
Free Article
18.

Calcium-dependent 86 Rb efflux and ethanol intoxication: studies of human red blood cells and rodent brain synaptosomes.

Yamamoto HA, Harris RA.

Eur J Pharmacol. 1983 Apr 8;88(4):357-63.

PMID:
6861876
[PubMed - indexed for MEDLINE]
19.

Selective intermediate-/small-conductance calcium-activated potassium channel (KCNN4) blockers are potent and effective therapeutics in experimental brain oedema and traumatic brain injury caused by acute subdural haematoma.

Mauler F, Hinz V, Horváth E, Schuhmacher J, Hofmann HA, Wirtz S, Hahn MG, Urbahns K.

Eur J Neurosci. 2004 Oct;20(7):1761-8.

PMID:
15379997
[PubMed - indexed for MEDLINE]
20.

Design, synthesis, and BK channel-opening activity of hexahydrodibenzazepinone derivatives.

Tashima T, Toriumi Y, Mochizuki Y, Nonomura T, Nagaoka S, Furukawa K, Tsuru H, Adachi-Akahane S, Ohwada T.

Bioorg Med Chem. 2006 Dec 1;14(23):8014-31. Epub 2006 Aug 10. Erratum in: Bioorg Med Chem. 2007 Feb 15;15(4):1878.

PMID:
16904328
[PubMed - indexed for MEDLINE]

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