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Items: 1 to 20 of 85

1.

The protein acetyltransferase ARD1: a novel cancer drug target?

Arnesen T, Thompson PR, Varhaug JE, Lillehaug JR.

Curr Cancer Drug Targets. 2008 Nov;8(7):545-53. Review.

PMID:
18991565
2.
3.

Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex.

Arnesen T, Gromyko D, Pendino F, Ryningen A, Varhaug JE, Lillehaug JR.

Oncogene. 2006 Jul 20;25(31):4350-60. Epub 2006 Mar 6.

PMID:
16518407
4.

Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation.

Seo JH, Cha JH, Park JH, Jeong CH, Park ZY, Lee HS, Oh SH, Kang JH, Suh SW, Kim KH, Ha JY, Han SH, Kim SH, Lee JW, Park JA, Jeong JW, Lee KJ, Oh GT, Lee MN, Kwon SW, Lee SK, Chun KH, Lee SJ, Kim KW.

Cancer Res. 2010 Jun 1;70(11):4422-32. doi: 10.1158/0008-5472.CAN-09-3258. Epub 2010 May 25.

5.

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.

Arnesen T, Anderson D, Baldersheim C, Lanotte M, Varhaug JE, Lillehaug JR.

Biochem J. 2005 Mar 15;386(Pt 3):433-43.

6.

Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin.

Lim JH, Chun YS, Park JW.

Cancer Res. 2008 Jul 1;68(13):5177-84. doi: 10.1158/0008-5472.CAN-07-6234.

7.

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.

Arnesen T, Betts MJ, Pendino F, Liberles DA, Anderson D, Caro J, Kong X, Varhaug JE, Lillehaug JR.

BMC Biochem. 2006 Apr 25;7:13.

8.

Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.

Arnesen T, Gromyko D, Horvli O, Fluge Ø, Lillehaug J, Varhaug JE.

Thyroid. 2005 Oct;15(10):1131-6.

PMID:
16279846
9.

A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1).

Arnesen T, Gromyko D, Kagabo D, Betts MJ, Starheim KK, Varhaug JE, Anderson D, Lillehaug JR.

BMC Biochem. 2009 May 29;10:15. doi: 10.1186/1471-2091-10-15.

10.

Acetylation of proteins as novel target for antitumor therapy: review article.

Di Gennaro E, Bruzzese F, Caraglia M, Abruzzese A, Budillon A.

Amino Acids. 2004 Jul;26(4):435-41. Epub 2004 Jun 11. Review.

PMID:
15290351
11.

Histone acetylation and the cell-cycle in cancer.

Wang C, Fu M, Mani S, Wadler S, Senderowicz AM, Pestell RG.

Front Biosci. 2001 Apr 1;6:D610-29. Review.

PMID:
11282573
12.

Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex.

Arnesen T, Anderson D, Torsvik J, Halseth HB, Varhaug JE, Lillehaug JR.

Gene. 2006 Apr 26;371(2):291-5. Epub 2006 Feb 28.

PMID:
16507339
13.

Purified recombinant hARD1 does not catalyse acetylation of Lys532 of HIF-1alpha fragments in vitro.

Murray-Rust TA, Oldham NJ, Hewitson KS, Schofield CJ.

FEBS Lett. 2006 Apr 3;580(8):1911-8. Epub 2006 Feb 17.

14.

Novel strategies in cancer therapeutics: targeting enzymes involved in cell cycle regulation and cellular proliferation.

Liu MC, Marshall JL, Pestell RG.

Curr Cancer Drug Targets. 2004 Aug;4(5):403-24. Review.

PMID:
15320717
15.

Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: a work in progress.

Gabrielli BG, Johnstone RW, Saunders NA.

Curr Cancer Drug Targets. 2002 Dec;2(4):337-53. Review.

PMID:
12470210
16.

Correlation of expression of human arrest-defective-1 (hARD1) protein with breast cancer.

Yu M, Ma M, Huang C, Yang H, Lai J, Yan S, Li L, Xiang M, Tan D.

Cancer Invest. 2009 Dec;27(10):978-83. doi: 10.3109/07357900902769723.

PMID:
19909012
17.
18.

Protein deacetylases: enzymes with functional diversity as novel therapeutic targets.

Yoshida M, Shimazu T, Matsuyama A.

Prog Cell Cycle Res. 2003;5:269-78. Review.

PMID:
14593721
19.

Characterization of ARD1 variants in mammalian cells.

Kim SH, Park JA, Kim JH, Lee JW, Seo JH, Jung BK, Chun KH, Jeong JW, Bae MK, Kim KW.

Biochem Biophys Res Commun. 2006 Feb 10;340(2):422-7. Epub 2005 Dec 15.

PMID:
16376303
20.

Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents.

Kim DH, Kim M, Kwon HJ.

J Biochem Mol Biol. 2003 Jan 31;36(1):110-9. Review.

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