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Aldosterone activates NF-kappaB in the collecting duct.

Leroy V, De Seigneux S, Agassiz V, Hasler U, Rafestin-Oblin ME, Vinciguerra M, Martin PY, Féraille E.

J Am Soc Nephrol. 2009 Jan;20(1):131-44. doi: 10.1681/ASN.2008020232. Epub 2008 Nov 5.


NF-kappaB inhibits sodium transport via down-regulation of SGK1 in renal collecting duct principal cells.

de Seigneux S, Leroy V, Ghzili H, Rousselot M, Nielsen S, Rossier BC, Martin PY, Féraille E.

J Biol Chem. 2008 Sep 12;283(37):25671-81. doi: 10.1074/jbc.M803812200. Epub 2008 Jun 27.


Aldosterone stimulates nuclear factor-kappa B activity and transcription of intercellular adhesion molecule-1 and connective tissue growth factor in rat mesangial cells via serum- and glucocorticoid-inducible protein kinase-1.

Terada Y, Ueda S, Hamada K, Shimamura Y, Ogata K, Inoue K, Taniguchi Y, Kagawa T, Horino T, Takao T.

Clin Exp Nephrol. 2012 Feb;16(1):81-8. doi: 10.1007/s10157-011-0498-x. Epub 2011 Nov 1. Review.


Aldosterone-stimulated SGK1 activity mediates profibrotic signaling in the mesangium.

Terada Y, Kuwana H, Kobayashi T, Okado T, Suzuki N, Yoshimoto T, Hirata Y, Sasaki S.

J Am Soc Nephrol. 2008 Feb;19(2):298-309. doi: 10.1681/ASN.2007050531. Epub 2008 Jan 9.


Toll-like receptor 4 activates NF-κB and MAP kinase pathways to regulate expression of proinflammatory COX-2 in renal medullary collecting duct cells.

Küper C, Beck FX, Neuhofer W.

Am J Physiol Renal Physiol. 2012 Jan 1;302(1):F38-46. doi: 10.1152/ajprenal.00590.2010. Epub 2011 Sep 21.


Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells.

Flores SY, Loffing-Cueni D, Kamynina E, Daidié D, Gerbex C, Chabanel S, Dudler J, Loffing J, Staub O.

J Am Soc Nephrol. 2005 Aug;16(8):2279-87. Epub 2005 Jun 15.


Ultraviolet B radiation activates NF-κB and induces iNOS expression in HR-1 hairless mouse skin: role of IκB kinase-β.

Chang EJ, Kundu JK, Liu L, Shin JW, Surh YJ.

Mol Carcinog. 2011 Apr;50(4):310-7. doi: 10.1002/mc.20646.


Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB.

Grotterød I, Maelandsmo GM, Boye K.

BMC Cancer. 2010 May 28;10:241. doi: 10.1186/1471-2407-10-241.


Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha.

Zhang W, Xia X, Reisenauer MR, Rieg T, Lang F, Kuhl D, Vallon V, Kone BC.

J Clin Invest. 2007 Mar;117(3):773-83.


Early nongenomic events in aldosterone action in renal collecting duct cells: PKCalpha activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response.

Le Moëllic C, Ouvrard-Pascaud A, Capurro C, Cluzeaud F, Fay M, Jaisser F, Farman N, Blot-Chabaud M.

J Am Soc Nephrol. 2004 May;15(5):1145-60.


SGK1 phosphorylation of IkappaB Kinase alpha and p300 Up-regulates NF-kappaB activity and increases N-Methyl-D-aspartate receptor NR2A and NR2B expression.

Tai DJ, Su CC, Ma YL, Lee EH.

J Biol Chem. 2009 Feb 13;284(7):4073-89. doi: 10.1074/jbc.M805055200. Epub 2008 Dec 16.


IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation.

Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2689-94. Epub 2006 Feb 13.


Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.

Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.

Oncogene. 2007 Feb 22;26(8):1201-12. Epub 2006 Aug 21.

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