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18981112,30134798,20870943,19715998,12021304,17675476,21469094,28423181,18635688,23121975,31288845,21723222,19286352,17182552,17699744,17695668,12486105,31356169,21469103,26070317,22564681,19665867,23769057,17114433,17182553,21312192,24604878,22935591,25405209,23200824,24725555,30612787,27037189,17438065,21314640,25362183,30915372,18493985,15905592,19931266,19839007,16763205,14676299,19768696,20686126,28895168,16612280,19050244,25833958,16918694,17911604,16799337,21469093,20172352,23313049,31703440,19941127,21525388,18199417,16966495,22984435,23878314,17513718,25381698,22636320,24798620,24082013,16627758,17681173,18599457,17513751,20498359,25619457,22613676,27166558,23657628,22472775,19204112,18684939,26728371,31921114,19635560,22972928,21389253,19234174,20626386,23998604,21745448,17548623,17620361,17307871,27142025,32296431,30248398,19917707,18322168,19307989,16887988,17991714,18778287,11807005,23861553,20729332,18097034,23627732,34882757,19941313,22773728,25027601,19174473,19801514,32595012,17548603,20181882,30159904,31563695,21525380,18424717,23547099,18477807,24018532,31059096,23872920,24082012,31554694,19841178,20154220,33524161,32610077,18453575,20017191,20584884,15557141,20394075,23298832,22855393,17204652,23576744,18513999,21386826,15611232,19017942,20041142,25684698,20333625,22538855,21646390,30936873,31681288,18424705,22792275,21630253,19079228,21621978,18266851,23804268,19291704,16630027,18308639,21423069,30634133,16368522,9286368,31715648,31053627,32533319,17371954,30616979,19499519,21813777,24086630,24155942,20179931,15514008,18557727,26908164,18941236,19387433,20864093,32057353,17548601,17944899,30896871,18713984,22736794,23272135,23834659,33171217,22031758,21555530,21779356,31235250,32849526,19468296,24829416,23801989,23762101,22147811,35140132,23359509,31427630,23733880,21839624,24700192,23152564,31167776,22678900,18566377,17371955,19950173,25041369,25174446,18159907,14707074,16849462,29477579,18453622,23630352,24708418,18419605,18430797,30623416,20101618,34282811,17878367,11560993,21576507,19943263,15728488,31031751,31134074,28800255,18710931,17114434,32245005,24673126,31545219,17802642,34298400,23847198,17878345,18981113,14734731,36000308,19135256,22966002,17331111,22912740,32656268,23874581,24337378,36635667,23667113,17548589,31194988,24271843,23482932,21469126,30989431,9107416,18714045,22952871,23322377,22615402,30510554,19414758,32366581,17073555,22988034,33679806,20395442,25108241,18727627,18272486,19424018,17356131,17785778,36301031,26605529,19924236,17449799,31608056,20483724,29439835,16478884,29686677,33248367,30926808,31653719,36837407,21068375,25202978,29743613,19039774,18763025,29669285,16329648,22767247,22678899,19949075,19168629,17548611,28750075,22678911,27837018,25177709,19404982,19648226,24038083,22732595,31487646,20944006,18825748,33930308,20855871,22991461,24795361,18395859,22468961,27481847,31143783,24021877,18546144,22084406,34333043,34088744,22812187,19625278,28827353,16918480,21625598,33037141,36180627,22545147,21810602,17617588,30319599,24033604,30598454,22786769,20639482,33151564,32661685,19405173,18832670,18802052,20018690,18832678,18306983,33811758,15294948,31103439,21355864,23446139,17984984,20408897,21717078,31578269,35569570,24980778,26070485,24198406,15661897,16030186,21728170,21496498,21655250,30981619,30700986,33406939,19890066,19667061,20018763,30546010,21460203,31265764,19262503,19651619,24616502,22681667,31209405,30626970,24022275,20187301,15479730,32508814,31140734,21502514,30613389,24934597,30793469,25949867,19073916,17869133,23460735,21889557,26341400,20967853,31924477,20108139,24454872,18792404,21873519,17483450,34843936,25348622,32235689,19342642,36700764,23547101,30297856,18998771,19079226,33479901,32210595,21287397,32279926,30652081,32421955,27992401,36621062,20672742,23844100,21463982,18632653,31109864,17202349,24194771,24040101,20480503,19464988,18071334,19252500,19174509,16106066,19657087,24337381,29728511,34764952,22219322,19414769,26937228,16918481,19741161,18778953,24550919,29904967,31601741,36177042,18799144,21414341,18566396,23021222,24442443,19767511,23532986,19692636,32017635,30366517,28581446,24083711,19401386,36341394,20427765,22900010,31569411,22466646,21697460,36427305,32424367,18077005,24712462,20953201,21056730,25695838,36283488,22850422,33529803,19567830,19188497,20705860,32461639,19079166,20373289,24194584,19918314,33385440,31949209,29455474,35593538,33250156,33275279,23502855,35609830,34777358,18328743,24938747,19530994,22285546,22760781,26453377,36405994,16785533,23677472,21876039,24192911,31472079,34980329,36157915,20958318,19003206,18424714,19371709,31434282,18195091,33922658,32522714,36108422,17552881,21818088,18097026,22043296,33166410,10611756,30584695,30004858,35874774,24744792,31494959,33288832,19720221,29323337,21822298,35693780,34728795,34923142,37121977,35359955,23509139,31952778,32133958,35786711,33753509,25629976,21711933,36928178,36581745,36135173,33671884,35042789,22941509,36345699,35404689,34450252,17979848,27574642,24979767,25039245,26405564,34748687,31002601,34664819,19673035,21287328,22694797,32372062,24238038,25215190,31670995,24434323,33613572,33997181,22737152,20958321,23291929,19272184,31786417,20582233,28738017,32737949,17823690,29977885,30089271,32774504,22737153,33665631,27141310,27175277,33531485,30059361,36721426,20671597,22500950,1686999,29615971,22752759,24550907,36332356,29484183,24516726,18508641,23526672,25076948,21833719,24498544,37028427,23226789,31308543,23539396,37143298,14711433,22720237,33364577,26635807,32199198,20717099,27376108,33180093,30847194,20963944,31784682,20879168,21779034,31213718,32327754[uid]

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CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells.

Yamazaki S, Dudziak D, Heidkamp GF, Fiorese C, Bonito AJ, Inaba K, Nussenzweig MC, Steinman RM. Yamazaki S, et al. J Immunol. 2008 Nov 15;181(10):6923-33. doi: 10.4049/jimmunol.181.10.6923. J Immunol. 2008. PMID: 18981112 Free PMC article.

Targeting DEC-205^-DCIR2⁺ dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis.

Tabansky I, Keskin DB, Watts D, Petzold C, Funaro M, Sands W, Wright P, Yunis EJ, Najjar S, Diamond B, Cao Y, Mooney D, Kretschmer K, Stern JNH. Tabansky I, et al. Mol Med. 2018 May 3;24(1):17. doi: 10.1186/s10020-018-0017-6. Mol Med. 2018. PMID: 30134798 Free PMC article.

Tolerogenic dendritic cells induce CD4+CD25hiFoxp3+ regulatory T cell differentiation from CD4+CD25-/loFoxp3- effector T cells.

Huang H, Dawicki W, Zhang X, Town J, Gordon JR. Huang H, et al. J Immunol. 2010 Nov 1;185(9):5003-10. doi: 10.4049/jimmunol.0903446. Epub 2010 Sep 24. J Immunol. 2010. PMID: 20870943

Transforming growth factor-beta and all-trans retinoic acid generate ex vivo transgenic regulatory T cells with intestinal homing receptors.

Moore C, Sauma D, Morales J, Bono MR, Rosemblatt M, Fierro JA. Moore C, et al. Transplant Proc. 2009 Jul-Aug;41(6):2670-2. doi: 10.1016/j.transproceed.2009.06.130. Transplant Proc. 2009. PMID: 19715998

CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules.

Morón G, Rueda P, Casal I, Leclerc C. Morón G, et al. J Exp Med. 2002 May 20;195(10):1233-45. doi: 10.1084/jem.20011930. J Exp Med. 2002. PMID: 12021304 Free PMC article.

Selective expansion of foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells.

Matsumura Y, Kobayashi T, Ichiyama K, Yoshida R, Hashimoto M, Takimoto T, Tanaka K, Chinen T, Shichita T, Wyss-Coray T, Sato K, Yoshimura A. Matsumura Y, et al. J Immunol. 2007 Aug 15;179(4):2170-9. doi: 10.4049/jimmunol.179.4.2170. J Immunol. 2007. PMID: 17675476

Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells.

Azukizawa H, Döhler A, Kanazawa N, Nayak A, Lipp M, Malissen B, Autenrieth I, Katayama I, Riemann M, Weih F, Berberich-Siebelt F, Lutz MB. Azukizawa H, et al. Eur J Immunol. 2011 May;41(5):1420-34. doi: 10.1002/eji.201040930. Epub 2011 Apr 14. Eur J Immunol. 2011. PMID: 21469094 Free article.

Mesenteric lymph node CD11b^- CD103⁺ PD-L1^High dendritic cells highly induce regulatory T cells.

Shiokawa A, Kotaki R, Takano T, Nakajima-Adachi H, Hachimura S. Shiokawa A, et al. Immunology. 2017 Sep;152(1):52-64. doi: 10.1111/imm.12747. Epub 2017 Jun 1. Immunology. 2017. PMID: 28423181 Free PMC article.

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation.

Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S. Onishi Y, et al. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10113-8. doi: 10.1073/pnas.0711106105. Epub 2008 Jul 17. Proc Natl Acad Sci U S A. 2008. PMID: 18635688 Free PMC article.

A distinct tolerogenic subset of splenic IDO(+)CD11b(+) dendritic cells from orally tolerized mice is responsible for induction of systemic immune tolerance and suppression of collagen-induced arthritis.

Park MJ, Park KS, Park HS, Cho ML, Hwang SY, Min SY, Park MK, Park SH, Kim HY. Park MJ, et al. Cell Immunol. 2012 Jul-Aug;278(1-2):45-54. doi: 10.1016/j.cellimm.2012.06.009. Epub 2012 Jul 10. Cell Immunol. 2012. PMID: 23121975

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