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Results: 1 to 20 of 103

Similar articles for PubMed (Select 18948576)

1.

A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.

Yin B, Delwel R, Valk PJ, Wallace MR, Loh ML, Shannon KM, Largaespada DA.

Blood. 2009 Jan 29;113(5):1075-85. doi: 10.1182/blood-2008-03-144436. Epub 2008 Oct 23.

2.

Nf1 mutant mice with p19ARF gene loss develop accelerated hematopoietic disease resembling acute leukemia with a variable phenotype.

Wiesner SM, Geurts JL, Diers MD, Bergerson RJ, Hasz DE, Morgan KJ, Largaespada DA.

Am J Hematol. 2011 Jul;86(7):579-85. doi: 10.1002/ajh.22035.

3.

Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.

Chang T, Krisman K, Theobald EH, Xu J, Akutagawa J, Lauchle JO, Kogan S, Braun BS, Shannon K.

J Clin Invest. 2013 Jan;123(1):335-9. doi: 10.1172/JCI63193. Epub 2012 Dec 10.

4.

Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia.

Gurevich RM, Rosten PM, Schwieger M, Stocking C, Humphries RK.

Exp Hematol. 2006 Sep;34(9):1192-201.

PMID:
16939812
5.

BCR-ABL but not JAK2 V617F inhibits erythropoiesis through the Ras signal by inducing p21CIP1/WAF1.

Tokunaga M, Ezoe S, Tanaka H, Satoh Y, Fukushima K, Matsui K, Shibata M, Tanimura A, Oritani K, Matsumura I, Kanakura Y.

J Biol Chem. 2010 Oct 8;285(41):31774-82. doi: 10.1074/jbc.M110.118653. Epub 2010 Jul 27.

6.

Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.

Largaespada DA, Brannan CI, Jenkins NA, Copeland NG.

Nat Genet. 1996 Feb;12(2):137-43.

PMID:
8563750
7.

Role of p21(WAF1/CIP1) as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells.

Forster K, Obermeier A, Mitina O, Simon N, Warmuth M, Krause G, Hallek M.

Ann Hematol. 2008 Mar;87(3):183-93. Epub 2007 Oct 25.

PMID:
17960378
8.

Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras.

Kalra R, Paderanga DC, Olson K, Shannon KM.

Blood. 1994 Nov 15;84(10):3435-9.

9.
10.

Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.

Cutts BA, Sjogren AK, Andersson KM, Wahlstrom AM, Karlsson C, Swolin B, Bergo MO.

Blood. 2009 Oct 22;114(17):3629-32. doi: 10.1182/blood-2009-02-205146. Epub 2009 Aug 26.

12.

Expression of cell cycle regulatory genes in chronic myelogenous leukemia.

Iolascon A, Della Ragione F, Giordani L, Serra A, Saglio G, Faienza MF.

Haematologica. 1998 Sep;83(9):771-7.

13.

Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.

Ingram DA, Hiatt K, King AJ, Fisher L, Shivakumar R, Derstine C, Wenning MJ, Diaz B, Travers JB, Hood A, Marshall M, Williams DA, Clapp DW.

J Exp Med. 2001 Jul 2;194(1):57-69.

14.

Patterns of hematopoietic lineage involvement in children with neurofibromatosis type 1 and malignant myeloid disorders.

Miles DK, Freedman MH, Stephens K, Pallavicini M, Sievers EL, Weaver M, Grunberger T, Thompson P, Shannon KM.

Blood. 1996 Dec 1;88(11):4314-20.

15.

Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia.

Gitler AD, Kong Y, Choi JK, Zhu Y, Pear WS, Epstein JA.

Pediatr Res. 2004 Apr;55(4):581-4. Epub 2004 Jan 22.

PMID:
14739366
16.

Mitotic recombination and compound-heterozygous mutations are predominant NF1-inactivating mechanisms in children with juvenile myelomonocytic leukemia and neurofibromatosis type 1.

Steinemann D, Arning L, Praulich I, Stuhrmann M, Hasle H, Stary J, Schlegelberger B, Niemeyer CM, Flotho C.

Haematologica. 2010 Feb;95(2):320-3. doi: 10.3324/haematol.2009.010355. Epub 2009 Dec 16.

17.

Bcl11a is essential for lymphoid development and negatively regulates p53.

Yu Y, Wang J, Khaled W, Burke S, Li P, Chen X, Yang W, Jenkins NA, Copeland NG, Zhang S, Liu P.

J Exp Med. 2012 Dec 17;209(13):2467-83. doi: 10.1084/jem.20121846. Epub 2012 Dec 10.

18.

Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment.

Miething C, Grundler R, Mugler C, Brero S, Hoepfl J, Geigl J, Speicher MR, Ottmann O, Peschel C, Duyster J.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4594-9. Epub 2007 Mar 5.

19.
20.

Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.

Ingram DA, Wenning MJ, Shannon K, Clapp DW.

Blood. 2003 Mar 1;101(5):1984-6. Epub 2002 Oct 17.

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