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Items: 1 to 20 of 92

1.

Combination chemical genetics.

Lehár J, Stockwell BR, Giaever G, Nislow C.

Nat Chem Biol. 2008 Nov;4(11):674-81. doi: 10.1038/nchembio.120. Review.

2.

Allele-specific behavior of molecular networks: understanding small-molecule drug response in yeast.

Zhang F, Gao B, Xu L, Li C, Hao D, Zhang S, Zhou M, Su F, Chen X, Zhi H, Li X.

PLoS One. 2013;8(1):e53581. doi: 10.1371/journal.pone.0053581. Epub 2013 Jan 4.

3.

The Yeast Systems Biology Network: mating communities.

Hohmann S.

Curr Opin Biotechnol. 2005 Jun;16(3):356-60. Review.

PMID:
15961037
4.

Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.

Aardema MJ, MacGregor JT.

Mutat Res. 2002 Jan 29;499(1):13-25. Review.

PMID:
11804602
5.

Chemical combination effects predict connectivity in biological systems.

Lehár J, Zimmermann GR, Krueger AS, Molnar RA, Ledell JT, Heilbut AM, Short GF 3rd, Giusti LC, Nolan GP, Magid OA, Lee MS, Borisy AA, Stockwell BR, Keith CT.

Mol Syst Biol. 2007;3:80. Epub 2007 Feb 27.

6.

Predicting phenotypic effects of gene perturbations in C. elegans using an integrated network model.

Borgwardt K.

Bioessays. 2008 Aug;30(8):707-10. doi: 10.1002/bies.20783. Review.

PMID:
18618771
7.

Can single knockouts accurately single out gene functions?

Deutscher D, Meilijson I, Schuster S, Ruppin E.

BMC Syst Biol. 2008 Jun 18;2:50. doi: 10.1186/1752-0509-2-50.

9.

The end of "naive reductionism": rise of systems biology or renaissance of physiology?

Strange K.

Am J Physiol Cell Physiol. 2005 May;288(5):C968-74. Review.

10.

Combining functional genomics and chemical biology to identify targets of bioactive compounds.

Ho CH, Piotrowski J, Dixon SJ, Baryshnikova A, Costanzo M, Boone C.

Curr Opin Chem Biol. 2011 Feb;15(1):66-78. doi: 10.1016/j.cbpa.2010.10.023. Epub 2010 Nov 17. Review.

PMID:
21093351
11.

High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.

Hoepfner D, Helliwell SB, Sadlish H, Schuierer S, Filipuzzi I, Brachat S, Bhullar B, Plikat U, Abraham Y, Altorfer M, Aust T, Baeriswyl L, Cerino R, Chang L, Estoppey D, Eichenberger J, Frederiksen M, Hartmann N, Hohendahl A, Knapp B, Krastel P, Melin N, Nigsch F, Oakeley EJ, Petitjean V, Petersen F, Riedl R, Schmitt EK, Staedtler F, Studer C, Tallarico JA, Wetzel S, Fishman MC, Porter JA, Movva NR.

Microbiol Res. 2014 Feb-Mar;169(2-3):107-20. doi: 10.1016/j.micres.2013.11.004. Epub 2013 Dec 1.

12.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
13.

Search for organising principles: understanding in systems biology.

Mesarovic MD, Sreenath SN, Keene JD.

Syst Biol (Stevenage). 2004 Jun;1(1):19-27. Review.

PMID:
17052112
14.

Identifying responsive modules by mathematical programming: an application to budding yeast cell cycle.

Wen Z, Liu ZP, Yan Y, Piao G, Liu Z, Wu J, Chen L.

PLoS One. 2012;7(7):e41854. doi: 10.1371/journal.pone.0041854. Epub 2012 Jul 25.

15.

The impact of systems approaches on biological problems in drug discovery.

Hood L, Perlmutter RM.

Nat Biotechnol. 2004 Oct;22(10):1215-7. No abstract available.

PMID:
15470453
16.

Quantitative analysis of genetic and neuronal multi-perturbation experiments.

Kaufman A, Keinan A, Meilijson I, Kupiec M, Ruppin E.

PLoS Comput Biol. 2005 Nov;1(6):e64. Epub 2005 Nov 25.

17.

Chemical genetics: tailoring tools for cell biology.

Mayer TU.

Trends Cell Biol. 2003 May;13(5):270-7. Review.

PMID:
12742171
18.

Modularity: a new perspective in biology.

Dani DN, Sainis JK.

Indian J Biochem Biophys. 2007 Jun;44(3):133-9. Review.

PMID:
17650580
19.

Editorial: Accelerating systems biology.

Mazza T.

Brief Bioinform. 2010 May;11(3):267-9. doi: 10.1093/bib/bbq012. No abstract available.

20.

Chemical-genetic approaches for exploring the mode of action of natural products.

Lopez A, Parsons AB, Nislow C, Giaever G, Boone C.

Prog Drug Res. 2008;66:237, 239-71. Review.

PMID:
18416308
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