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Results: 1 to 20 of 88

1.

PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.

Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener DR, Thompson CB, Diehl JA.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16314-9. doi: 10.1073/pnas.0808517105. Epub 2008 Oct 13.

PMID:
18852460
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection.

Yu Y, Pierciey FJ Jr, Maguire TG, Alwine JC.

PLoS Pathog. 2013;9(4):e1003266. doi: 10.1371/journal.ppat.1003266. Epub 2013 Apr 4.

PMID:
23592989
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.

Koumenis C, Naczki C, Koritzinsky M, Rastani S, Diehl A, Sonenberg N, Koromilas A, Wouters BG.

Mol Cell Biol. 2002 Nov;22(21):7405-16.

PMID:
12370288
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation.

Sequeira SJ, Ranganathan AC, Adam AP, Iglesias BV, Farias EF, Aguirre-Ghiso JA.

PLoS One. 2007 Jul 18;2(7):e615.

PMID:
17637831
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.

Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR, Imaizumi K.

J Biol Chem. 2011 Feb 11;286(6):4809-18. doi: 10.1074/jbc.M110.152900. Epub 2010 Dec 6.

PMID:
21135100
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation.

Bobrovnikova-Marjon E, Pytel D, Riese MJ, Vaites LP, Singh N, Koretzky GA, Witze ES, Diehl JA.

Mol Cell Biol. 2012 Jun;32(12):2268-78. doi: 10.1128/MCB.00063-12. Epub 2012 Apr 9.

PMID:
22493067
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.

Liang SH, Zhang W, McGrath BC, Zhang P, Cavener DR.

Biochem J. 2006 Jan 1;393(Pt 1):201-9.

PMID:
16124869
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Salicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner.

Silva AM, Wang D, Komar AA, Castilho BA, Williams BR.

J Biol Chem. 2007 Apr 6;282(14):10164-71. Epub 2007 Feb 6.

PMID:
17284450
[PubMed - indexed for MEDLINE]
Free Article
9.

Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.

Bettaieb A, Matsuo K, Matsuo I, Wang S, Melhem R, Koromilas AE, Haj FG.

PLoS One. 2012;7(4):e34412. doi: 10.1371/journal.pone.0034412. Epub 2012 Apr 3.

PMID:
22509299
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway.

Hamanaka RB, Bennett BS, Cullinan SB, Diehl JA.

Mol Biol Cell. 2005 Dec;16(12):5493-501. Epub 2005 Sep 21.

PMID:
16176978
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment.

Avivar-Valderas A, Salas E, Bobrovnikova-Marjon E, Diehl JA, Nagi C, Debnath J, Aguirre-Ghiso JA.

Mol Cell Biol. 2011 Sep;31(17):3616-29. doi: 10.1128/MCB.05164-11. Epub 2011 Jun 27.

PMID:
21709020
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum.

Wu S, Hu Y, Wang JL, Chatterjee M, Shi Y, Kaufman RJ.

J Biol Chem. 2002 May 17;277(20):18077-83. Epub 2002 Mar 4.

PMID:
11877419
[PubMed - indexed for MEDLINE]
Free Article
15.

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK.

Marciniak SJ, Garcia-Bonilla L, Hu J, Harding HP, Ron D.

J Cell Biol. 2006 Jan 16;172(2):201-9.

PMID:
16418533
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Multiple differentiation pathways of rat mammary stromal cells in vitro: acquisition of a fibroblast, adipocyte or endothelial phenotype is dependent on hormonal and extracellular matrix stimulation.

Zangani D, Darcy KM, Masso-Welch PA, Bellamy ES, Desole MS, Ip MM.

Differentiation. 1999 Jan;64(2):91-101.

PMID:
10234806
[PubMed - indexed for MEDLINE]
17.

PERK-dependent regulation of IAP translation during ER stress.

Hamanaka RB, Bobrovnikova-Marjon E, Ji X, Liebhaber SA, Diehl JA.

Oncogene. 2009 Feb 12;28(6):910-20. doi: 10.1038/onc.2008.428. Epub 2008 Nov 24.

PMID:
19029953
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling.

Qiu W, Su Q, Rutledge AC, Zhang J, Adeli K.

J Lipid Res. 2009 Sep;50(9):1814-23. doi: 10.1194/jlr.M800343-JLR200. Epub 2009 Apr 21.

PMID:
19383982
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Promastigote to amastigote differentiation of Leishmania is markedly delayed in the absence of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation.

Chow C, Cloutier S, Dumas C, Chou MN, Papadopoulou B.

Cell Microbiol. 2011 Jul;13(7):1059-77. doi: 10.1111/j.1462-5822.2011.01602.x. Epub 2011 May 30.

PMID:
21624030
[PubMed - indexed for MEDLINE]
20.

FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways.

Jiao P, Ma J, Feng B, Zhang H, Diehl JA, Chin YE, Yan W, Xu H.

Obesity (Silver Spring). 2011 Mar;19(3):483-91. doi: 10.1038/oby.2010.200. Epub 2010 Sep 9.

PMID:
20829802
[PubMed - indexed for MEDLINE]

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